3. BOFdat step3

3.1. Finding specie-specific metabolic end goals

from BOFdat import step3
import pandas as pd
import cobra
import os

/home/jean-christophe/.local/lib/python2.7/site-packages/pip/_vendor/requests/__init__.py:83: RequestsDependencyWarning: Old version of cryptography ([1, 2, 3]) may cause slowdown.
  warnings.warn(warning, RequestsDependencyWarning)

3.2. Example using the E.coli genome-scale model iML1515 and the biomass objective function generate in BOFdat step2

Metabolic end goals may vary considerably from one specie to another. For instance, the peptidoglycan that are present on the surface of E.coli may be slightly different in another gram-negative bacteria and completely absent from a gram-positive. This example is obvious for components that define the cell’s visible phenotype but what should one do when the metabolites do not completely change the cell’s phenotype. The identification of these seemingly invisible specie-specific crucial metabolites is the goal of the Step3 of BOFdat.

Using the metaheuristic genetic algorithm, BOFdat finds the biomass composition that allows to best replicate gene essentiality.

3.2.1. Steps

1. Generate an initial population
2. Generate optimal biomass compositions
3. Cluster the metabolic end goals
4. Determine stoichiometric coefficients
5. Update

3.2.2. Generate an initial population

In BOFdat step3, a genetic algorithm is implemented to define the optimal biomass composition. The individuals subjected to the evolution are indexed boolean lists where each position correspond to a defined metabolite. The genetic algorithm requires that an initial population of these individuals be generated. To do so BOFdat first screens the entire model for solvable metabolites and then generates lists of metabolites (inviduals).

3.3. Inputs

3.3.1. Initial population

- Population name (string)
- Experimental essentiality (2 column CSV)
- Model (JSON or SBML)
- Path to the BOF of BOFdat Step 2 (CSV)

3.3.2. Genetic algorithm

- Model (JSON or SBML)
- Initial population (CSV)
- Experimental essentiality, gene identifier and binary essentiality (CSV)
- Path to the BOF of BOFdat Step 2 (CSV)
- Hall of Fame name (string)
- Logbook name (string)

3.3.3. Spatial clustering

- Path to output (string)
- Model (JSON or SBML)
- Connectivity threshold for removal of metabolites in calculation of distance matrix (int)
- MCC threshold for selection of individuals (float)

#Inputs to generate the initial population
population_name = 'data/Populations/test_pop'
path_to_model = 'data/iML1515.json'
base_biomass_path = 'data/bofdat_step2.csv'
exp_essentiality_path = 'data/glucose_essentiality.csv'

step3.generate_initial_population(population_name,
                                  path_to_model,
                                  base_biomass_path,
                                  exp_essentiality_path,
                                  number_of_populations=5)

Assessing individual metabolite solvability
4

/home/jean-christophe/.local/lib/python2.7/site-packages/BOFdat-0.2.0-py2.7.egg/BOFdat/util/update.py:20 UserWarning: File has 3 columns, assuming index on first column

(<Metabolite 2pg_c at 0x7f3b146d5b10>, True)
(<Metabolite 13dpg_c at 0x7f3b07e41e50>, True)
(<Metabolite prbamp_c at 0x7f3b07e41ed0>, True)
(<Metabolite grdp_c at 0x7f3b14c7b050>, True)
(<Metabolite dms_e at 0x7f3b07e41e90>, False)
(<Metabolite fpram_c at 0x7f3b07e41e10>, True)
(<Metabolite dcyt_p at 0x7f3b157e0bd0>, False)
(<Metabolite fum_p at 0x7f3b146d5cd0>, True)
(<Metabolite tyr__L_p at 0x7f3b146d5b50>, True)
(<Metabolite feenter_e at 0x7f3b07e41fd0>, True)
(<Metabolite gg4abut_c at 0x7f3b5d4c3f10>, True)
(<Metabolite arbtn_e at 0x7f3b146d5dd0>, False)
(<Metabolite aso3_c at 0x7f3b146d5ed0>, False)
(<Metabolite cpgn_un_e at 0x7f3b146d5690>, False)
(<Metabolite alaala_e at 0x7f3b146d5410>, True)
(<Metabolite 3ohexACP_c at 0x7f3b146d5510>, False)
(<Metabolite 3ocddec5eACP_c at 0x7f3b146d5310>, False)
(<Metabolite clpn120_p at 0x7f3b146d5a50>, True)
(<Metabolite apg141_c at 0x7f3b15d6a910>, True)
(<Metabolite dca_c at 0x7f3b15d6a810>, True)
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(<Metabolite ala__L_e at 0x7f3b15d6aa10>, True)
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(<Metabolite g3pc_c at 0x7f3b07ee2a10>, False)
(<Metabolite dmbzid_c at 0x7f3b146d5250>, False)
(<Metabolite xtp_c at 0x7f3b15d6ae50>, True)
(<Metabolite cd2_c at 0x7f3b146d5fd0>, False)
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(<Metabolite mn2_c at 0x7f3b07ee2b10>, True)
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(<Metabolite 2agpg181_p at 0x7f3b07ee2d10>, True)
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(<Metabolite mocogdp_c at 0x7f3b146d52d0>, True)
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(<Metabolite co2_e at 0x7f3b07eeab50>, True)
(<Metabolite akg_e at 0x7f3b07eea550>, True)
(<Metabolite gsn_e at 0x7f3b07eea950>, True)
(<Metabolite pydx5p_c at 0x7f3b07ef2090>, True)
(<Metabolite 3dhgulnp_c at 0x7f3b07eea250>, False)
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(<Metabolite adphep_LD_c at 0x7f3b15d6a490>, True)
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(<Metabolite 12dgr181_p at 0x7f3b07eeae50>, True)
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(<Metabolite duri_c at 0x7f3b07ee2750>, True)
(<Metabolite ala_B_c at 0x7f3b07ef93d0>, True)
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(<Metabolite g6p_e at 0x7f3b15d70fd0>, False)
(<Metabolite hdcea_c at 0x7f3b15d70ed0>, True)
(<Metabolite acgam6p_c at 0x7f3b15d706d0>, True)
(<Metabolite thmpp_c at 0x7f3b15d70ad0>, True)
(<Metabolite val__L_p at 0x7f3b15a9e210>, True)
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(<Metabolite pyr_p at 0x7f3b15a9e110>, True)
(<Metabolite ni2_c at 0x7f3b15d700d0>, True)
(<Metabolite peamn_p at 0x7f3b15a9e710>, False)
(<Metabolite mso3_e at 0x7f3b15a9e510>, False)
(<Metabolite murein5p5p_p at 0x7f3b15a9e410>, True)
(<Metabolite thrp_e at 0x7f3b15d703d0>, False)
(<Metabolite octa_c at 0x7f3b15a9ed10>, True)
(<Metabolite 1odecg3p_p at 0x7f3b15d705d0>, True)
(<Metabolite LalaLglu_e at 0x7f3b07ef98d0>, False)
(<Metabolite mththf_c at 0x7f3b15a9e810>, True)
(<Metabolite sufbcd_2fe2s_c at 0x7f3b15a9ee10>, False)
(<Metabolite bwco_c at 0x7f3b15a9ef10>, True)
(<Metabolite f_p at 0x7f3b15a7f350>, False)
(<Metabolite fru_c at 0x7f3b15a9e910>, True)
(<Metabolite 2ahbut_c at 0x7f3b15a9ec10>, True)
(<Metabolite ump_c at 0x7f3b15d704d0>, True)
(<Metabolite 4c2me_c at 0x7f3b15a7f050>, True)
(<Metabolite ade_e at 0x7f3b146d53d0>, True)
(<Metabolite rmn_e at 0x7f3b15d70cd0>, False)
(<Metabolite 2dhguln_c at 0x7f3b15a7f650>, False)
(<Metabolite 2ddglcn_e at 0x7f3b15a7f850>, False)
(<Metabolite glyb_e at 0x7f3b15a7fa50>, False)
(<Metabolite glcr_e at 0x7f3b15a7f550>, False)
(<Metabolite cyan_c at 0x7f3b15a7f950>, False)
(<Metabolite cu2_e at 0x7f3b15d6af10>, True)
(<Metabolite 15dap_p at 0x7f3b15a7fe50>, True)
(<Metabolite ptrc_p at 0x7f3b15a7fd50>, True)
(<Metabolite arbtn_p at 0x7f3b15a7fc50>, False)
(<Metabolite 34dhpac_e at 0x7f3b15a7ff50>, False)
(<Metabolite anhgm_e at 0x7f3b15aad390>, True)
(<Metabolite cu2_p at 0x7f3b15aad090>, True)
(<Metabolite 14glucan_p at 0x7f3b15a9eb10>, False)
(<Metabolite pgp141_c at 0x7f3b14142350>, True)
(<Metabolite dsbard_p at 0x7f3b15aad290>, False)
(<Metabolite galctn__L_e at 0x7f3b15aad890>, False)
(<Metabolite pydxn_p at 0x7f3b14142250>, False)
(<Metabolite preq0_c at 0x7f3b15d708d0>, True)
(<Metabolite iscu_2fe2s_c at 0x7f3b15aad790>, False)
(<Metabolite novbcn_e at 0x7f3b15aadd90>, False)
(<Metabolite flxr_c at 0x7f3b15a9ea10>, False)
(<Metabolite lcts_c at 0x7f3b15a9e610>, False)
(<Metabolite 3ohdcoa_c at 0x7f3b15aad190>, True)
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(<Metabolite tcynt_c at 0x7f3b15a9b0d0>, False)
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(<Metabolite 3hodcoa_c at 0x7f3b15a9b2d0>, True)
(<Metabolite all__D_e at 0x7f3b15d6a3d0>, False)
(<Metabolite ca2_e at 0x7f3b15a9bad0>, True)
(<Metabolite fe2_p at 0x7f3b15a9b6d0>, True)
(<Metabolite g1p_e at 0x7f3b15d707d0>, False)
(<Metabolite udcpdp_p at 0x7f3b15a9b3d0>, True)
(<Metabolite ag_e at 0x7f3b15a9bfd0>, False)
(<Metabolite pa141_c at 0x7f3b15aad690>, True)
(<Metabolite cdpdddecg_c at 0x7f3b15aad590>, True)
(<Metabolite pe140_p at 0x7f3b15a9bdd0>, True)
(<Metabolite 2agpg120_c at 0x7f3b07ea6210>, True)
(<Metabolite 2tdecg3p_p at 0x7f3b15aadb90>, True)
(<Metabolite 2odecg3p_c at 0x7f3b15a9bcd0>, True)
(<Metabolite hdcoa_c at 0x7f3b15a7f450>, True)
(<Metabolite o16a4colipa_e at 0x7f3b15aadc90>, False)
(<Metabolite udcpgl_c at 0x7f3b141421d0>, True)
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(<Metabolite cyst__L_c at 0x7f3b07ea6ad0>, True)
(<Metabolite dutp_c at 0x7f3b141420d0>, True)
(<Metabolite dmlz_c at 0x7f3b15a9bed0>, True)
(<Metabolite pan4p_c at 0x7f3b07ea6310>, True)
(<Metabolite adprib_c at 0x7f3b07ea6ed0>, True)
(<Metabolite quln_c at 0x7f3b07ea6bd0>, True)
(<Metabolite dxyl_c at 0x7f3b07ea6fd0>, False)
(<Metabolite dhptd_c at 0x7f3b15a9bbd0>, True)
(<Metabolite lipa_c at 0x7f3b15a94110>, True)
(<Metabolite sheme_c at 0x7f3b07ea66d0>, True)
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(<Metabolite gal1p_p at 0x7f3b15a94510>, False)
(<Metabolite g3pe_e at 0x7f3b15a94910>, True)
(<Metabolite anhm3p_c at 0x7f3b15a94410>, True)
(<Metabolite clpn140_p at 0x7f3b07ea69d0>, True)
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(<Metabolite LalaDgluMdapDala_e at 0x7f3b15658c10>, True)
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(<Metabolite sucgsa_c at 0x7f3b141425d0>, True)
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(<Metabolite ocdcea_c at 0x7f3b156696d0>, True)
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(<Metabolite succ_p at 0x7f3b1565b150>, True)
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(<Metabolite maltttr_p at 0x7f3b1565bf50>, False)
(<Metabolite met__D_c at 0x7f3b15673290>, False)
(<Metabolite dtmp_p at 0x7f3b1565b850>, False)
(<Metabolite aso4_c at 0x7f3b1565be50>, False)
(<Metabolite acgal_p at 0x7f3b1565ba50>, False)
(<Metabolite cys__D_e at 0x7f3b15673190>, False)
(<Metabolite pgp160_p at 0x7f3b15673390>, True)
(<Metabolite cbm_c at 0x7f3b1565bc50>, True)
(<Metabolite pmeACP_c at 0x7f3b15673490>, False)
(<Metabolite r1p_c at 0x7f3b14142790>, True)
(<Metabolite 5mta_c at 0x7f3b15658f10>, True)
(<Metabolite val__L_e at 0x7f3b156699d0>, True)
(<Metabolite gdpofuc_c at 0x7f3b15673690>, True)
(<Metabolite chol_c at 0x7f3b15673d90>, False)
(<Metabolite malt_c at 0x7f3b15673a90>, False)
(<Metabolite rhcys_c at 0x7f3b15673590>, True)
(<Metabolite met__D_e at 0x7f3b1565b250>, False)
(<Metabolite gbbtn_c at 0x7f3b15673b90>, False)
(<Metabolite dmso_e at 0x7f3b15673c90>, False)
(<Metabolite r15bp_c at 0x7f3b141427d0>, True)
(<Metabolite g3pe_p at 0x7f3b15a282d0>, True)
(<Metabolite arab__D_c at 0x7f3b15673e90>, True)
(<Metabolite sulfac_c at 0x7f3b15a89990>, False)
(<Metabolite mg2_c at 0x7f3b15673f90>, True)
(<Metabolite acmalt_c at 0x7f3b15a286d0>, False)
(<Metabolite 1hdecg3p_c at 0x7f3b15673790>, True)
(<Metabolite pg141_p at 0x7f3b15a287d0>, True)
(<Metabolite apg181_c at 0x7f3b15673890>, True)
(<Metabolite pydx_p at 0x7f3b15a28cd0>, False)
(<Metabolite cellb_p at 0x7f3b15a284d0>, False)
(<Metabolite mal__L_c at 0x7f3b15658810>, True)
(<Metabolite urea_c at 0x7f3b15a28dd0>, True)
(<Metabolite 5apru_c at 0x7f3b15a04110>, True)
(<Metabolite pnto__R_c at 0x7f3b15a288d0>, True)
(<Metabolite gdptp_c at 0x7f3b15a04210>, True)
(<Metabolite 3hddcoa_c at 0x7f3b15a28fd0>, True)
(<Metabolite thymd_e at 0x7f3b14142590>, True)
(<Metabolite 5aizc_c at 0x7f3b15a285d0>, True)
(<Metabolite xu5p__L_c at 0x7f3b15a289d0>, False)
(<Metabolite hkntd_c at 0x7f3b15a04810>, False)
(<Metabolite sucr_p at 0x7f3b15a28ed0>, False)
(<Metabolite gmp_e at 0x7f3b15a04610>, False)
(<Metabolite isetac_p at 0x7f3b1565b750>, False)
(<Metabolite dhmptp_c at 0x7f3b15a04510>, True)
(<Metabolite alaala_p at 0x7f3b15a280d0>, True)
(<Metabolite thex2eACP_c at 0x7f3b15a28bd0>, False)
(<Metabolite t3c9palmeACP_c at 0x7f3b15a04e10>, False)
(<Metabolite cpe160_c at 0x7f3b15a04410>, True)
(<Metabolite lpp_p at 0x7f3b15a04a10>, False)
(<Metabolite 1agpe181_p at 0x7f3b15a28ad0>, True)
(<Metabolite ghb_c at 0x7f3b15669dd0>, True)
(<Metabolite LalaLglu_p at 0x7f3b15a04f10>, False)
(<Metabolite mdhdhf_c at 0x7f3b15a04c10>, True)
(<Metabolite moadamp_c at 0x7f3b15a32450>, False)
(<Metabolite mththf_p at 0x7f3b15a32050>, True)
(<Metabolite 3hbz_c at 0x7f3b15a32650>, False)
(<Metabolite prpmn_c at 0x7f3b141428d0>, False)
(<Metabolite acg5sa_c at 0x7f3b15a32750>, True)
(<Metabolite skm_c at 0x7f3b15a32b50>, True)
(<Metabolite imp_c at 0x7f3b14142950>, True)
(<Metabolite o2_c at 0x7f3b15a32850>, True)
(<Metabolite 3hbcoa_c at 0x7f3b15a04310>, True)
(<Metabolite s17bp_c at 0x7f3b15a32c50>, True)
(<Metabolite pydxn_c at 0x7f3b15a283d0>, True)
(<Metabolite sucorn_c at 0x7f3b15a32e50>, True)
(<Metabolite dhcinnm_c at 0x7f3b15a32d50>, False)
(<Metabolite idon__L_c at 0x7f3b15a32f50>, True)
(<Metabolite pac_c at 0x7f3b15a32150>, False)
(<Metabolite 3hpppn_e at 0x7f3b15a04b10>, False)
(<Metabolite ctbt_c at 0x7f3b15a36490>, False)
(<Metabolite tdeACP_c at 0x7f3b15a36290>, False)
(<Metabolite 23dhba_c at 0x7f3b15a36190>, True)
(<Metabolite ddcacoa_c at 0x7f3b15a36690>, True)
(<Metabolite his__L_p at 0x7f3b15a36990>, True)
(<Metabolite no2_p at 0x7f3b14142a10>, False)
(<Metabolite cd2_e at 0x7f3b15a36b90>, False)
(<Metabolite Nmtrp_c at 0x7f3b15a32a50>, False)
(<Metabolite icolipa_c at 0x7f3b15a36c90>, True)
(<Metabolite crn__D_p at 0x7f3b15a36590>, False)
(<Metabolite cd2_p at 0x7f3b14142910>, False)
(<Metabolite 2doxg6p_c at 0x7f3b15a36890>, False)
(<Metabolite murein4px4p4p_p at 0x7f3b15a36a90>, True)
(<Metabolite dt5hsu_c at 0x7f3b15673090>, False)
(<Metabolite slnt_p at 0x7f3b157590d0>, True)
(<Metabolite hgmeACP_c at 0x7f3b15a32350>, False)
(<Metabolite ttrcyc_p at 0x7f3b157591d0>, False)
(<Metabolite 2sephchc_c at 0x7f3b157596d0>, True)
(<Metabolite dhps_c at 0x7f3b157592d0>, False)
(<Metabolite mercpeth_c at 0x7f3b15a04d10>, False)
(<Metabolite puacgam_p at 0x7f3b14142490>, True)
(<Metabolite nadphx__S_c at 0x7f3b157594d0>, True)
(<Metabolite ncam_c at 0x7f3b157593d0>, True)
(<Metabolite sucbz_c at 0x7f3b15759dd0>, True)
(<Metabolite glx_c at 0x7f3b157595d0>, True)
(<Metabolite etoh_e at 0x7f3b15759cd0>, True)
(<Metabolite pro__L_e at 0x7f3b15759bd0>, True)
(<Metabolite ppp9_c at 0x7f3b15a36f90>, True)
(<Metabolite air_c at 0x7f3b157599d0>, True)
(<Metabolite 6hmhptpp_c at 0x7f3b15748310>, True)
(<Metabolite pydam_c at 0x7f3b15748110>, True)
(<Metabolite gam6p_e at 0x7f3b15a32950>, False)
(<Metabolite nac_e at 0x7f3b15748410>, False)
(<Metabolite galctn__D_c at 0x7f3b15748610>, False)
(<Metabolite micit_c at 0x7f3b15759fd0>, True)
(<Metabolite hdeACP_c at 0x7f3b14142b50>, False)
(<Metabolite acmana_p at 0x7f3b15748810>, False)
(<Metabolite nh4_p at 0x7f3b15759ed0>, True)
(<Metabolite cbi_p at 0x7f3b14142410>, False)
(<Metabolite gal_bD_e at 0x7f3b15748a10>, False)
(<Metabolite imp_p at 0x7f3b15748510>, False)
(<Metabolite glcur1p_p at 0x7f3b157597d0>, False)
(<Metabolite skm_p at 0x7f3b15748c10>, False)
(<Metabolite murein5px3p_p at 0x7f3b1574e050>, True)
(<Metabolite 2agpe161_p at 0x7f3b15a36d90>, True)
(<Metabolite 5dglcn_e at 0x7f3b15748e10>, True)
(<Metabolite dgslnt_c at 0x7f3b1574e350>, True)
(<Metabolite sufsesh_c at 0x7f3b15748b10>, False)
(<Metabolite 4abzglu_e at 0x7f3b15a36390>, True)
(<Metabolite lkdr_c at 0x7f3b1574e550>, True)
(<Metabolite 3hbzcoa_c at 0x7f3b1574e150>, False)
(<Metabolite xylu__D_c at 0x7f3b1574e450>, False)
(<Metabolite amet_c at 0x7f3b15673990>, True)
(<Metabolite h2s_c at 0x7f3b14142a50>, True)
(<Metabolite 3oocoa_c at 0x7f3b1574ed50>, True)
(<Metabolite acgam1p_c at 0x7f3b15748710>, True)
(<Metabolite malt_e at 0x7f3b1574ea50>, False)
(<Metabolite mn2_e at 0x7f3b15748910>, True)
(<Metabolite u23ga_c at 0x7f3b1574e750>, True)
(<Metabolite fuc__L_c at 0x7f3b15743390>, False)
(<Metabolite 4abutn_c at 0x7f3b15743090>, True)
(<Metabolite tma_e at 0x7f3b1574ee50>, False)
(<Metabolite occoa_c at 0x7f3b157598d0>, True)
(<Metabolite lyx__L_e at 0x7f3b15743490>, False)
(<Metabolite gtp_e at 0x7f3b15743190>, False)
(<Metabolite man6p_p at 0x7f3b1574ef50>, False)
(<Metabolite fecrm_un_c at 0x7f3b15748210>, False)
(<Metabolite lipa_cold_p at 0x7f3b15a32250>, True)
(<Metabolite murein3p3p_p at 0x7f3b14142990>, True)
(<Metabolite hexACP_c at 0x7f3b1574eb50>, False)
(<Metabolite pg161_c at 0x7f3b14142d50>, True)
(<Metabolite pe120_p at 0x7f3b15743290>, True)
(<Metabolite ppal_p at 0x7f3b15743a90>, False)
(<Metabolite colipap_p at 0x7f3b1574e950>, True)
(<Metabolite dhps_p at 0x7f3b15743990>, False)
(<Metabolite 2hptcl_c at 0x7f3b15743f90>, False)
(<Metabolite phpyr_c at 0x7f3b158dd0d0>, True)
(<Metabolite 4ampm_c at 0x7f3b1574e650>, True)
(<Metabolite fru_e at 0x7f3b158dd1d0>, False)
(<Metabolite pyr_e at 0x7f3b15743e90>, True)
(<Metabolite dtdp4addg_c at 0x7f3b158dd3d0>, True)
(<Metabolite unagamuf_c at 0x7f3b158dd5d0>, True)
(<Metabolite malttr_e at 0x7f3b1574e850>, False)
(<Metabolite 5mthf_c at 0x7f3b14142d90>, True)
(<Metabolite ppt_e at 0x7f3b158ddad0>, False)
(<Metabolite na1_p at 0x7f3b14142a90>, True)
(<Metabolite glyald_p at 0x7f3b158dd7d0>, True)
(<Metabolite rbl__D_c at 0x7f3b158dd4d0>, True)
(<Metabolite hom__L_e at 0x7f3b15743690>, True)
(<Metabolite dcmp_e at 0x7f3b158ca210>, False)
(<Metabolite dgmp_e at 0x7f3b158dded0>, False)
(<Metabolite fald_c at 0x7f3b158dd8d0>, False)
(<Metabolite 23ccmp_e at 0x7f3b15743790>, False)
(<Metabolite udpg_e at 0x7f3b158dddd0>, False)
(<Metabolite acgal_e at 0x7f3b1574e250>, False)
(<Metabolite 3ocvac11eACP_c at 0x7f3b158ca110>, False)
(<Metabolite 3hoctaACP_c at 0x7f3b158ddfd0>, False)
(<Metabolite 2agpe181_p at 0x7f3b158ddbd0>, True)
(<Metabolite ocdca_c at 0x7f3b158ca410>, True)
(<Metabolite 2agpg180_c at 0x7f3b158ca310>, True)
(<Metabolite 2tdec7eg3p_p at 0x7f3b14142890>, True)
(<Metabolite malcoame_c at 0x7f3b158cab10>, True)
(<Metabolite gmeACP_c at 0x7f3b14142bd0>, False)
(<Metabolite mpt_c at 0x7f3b158ca510>, True)
(<Metabolite 4crsol_c at 0x7f3b158cae10>, True)
(<Metabolite gam_c at 0x7f3b158c7150>, False)
(<Metabolite psuri_p at 0x7f3b158c7050>, False)
(<Metabolite g3p_c at 0x7f3b158cad10>, True)
(<Metabolite etoh_c at 0x7f3b158caf10>, True)
(<Metabolite so3_c at 0x7f3b158ddcd0>, True)
(<Metabolite aicar_c at 0x7f3b158c7250>, True)
(<Metabolite altrn_c at 0x7f3b15743b90>, False)
(<Metabolite fruur_c at 0x7f3b158c7450>, False)
(<Metabolite ac_e at 0x7f3b158ca710>, True)
(<Metabolite k_e at 0x7f3b158c7350>, True)
(<Metabolite lipidX_c at 0x7f3b14142e90>, True)
(<Metabolite mi1p__D_c at 0x7f3b158c7650>, False)
(<Metabolite taur_e at 0x7f3b14142f90>, False)
(<Metabolite glcn_p at 0x7f3b158ca810>, True)
(<Metabolite gua_p at 0x7f3b15743c90>, True)
(<Metabolite fe3hox_un_p at 0x7f3b158c7950>, False)
(<Metabolite xmp_e at 0x7f3b158cac10>, False)
(<Metabolite so3_p at 0x7f3b158c7d50>, False)
(<Metabolite glcur1p_e at 0x7f3b158dd9d0>, False)
(<Metabolite tdec2eACP_c at 0x7f3b15a3f390>, False)
(<Metabolite 3hpp_p at 0x7f3b15a3f090>, True)
(<Metabolite pimACP_c at 0x7f3b158ca610>, False)
(<Metabolite dhcholn_c at 0x7f3b15a3f590>, False)
(<Metabolite argsuc_c at 0x7f3b15a3f290>, True)
(<Metabolite chor_c at 0x7f3b158c7e50>, True)
(<Metabolite hom__L_c at 0x7f3b15a3f990>, True)
(<Metabolite thymd_c at 0x7f3b158c7c50>, True)
(<Metabolite dgdp_c at 0x7f3b15a3fb90>, True)
(<Metabolite glu1sa_c at 0x7f3b15a3f690>, True)
(<Metabolite cit_e at 0x7f3b158dd2d0>, True)
(<Metabolite leu__L_e at 0x7f3b15a3f790>, True)
(<Metabolite q8h2_c at 0x7f3b15a4a0d0>, True)
(<Metabolite ala__D_e at 0x7f3b15a3ff90>, True)
(<Metabolite fe2_e at 0x7f3b158c7850>, True)
(<Metabolite galt_e at 0x7f3b158c7750>, False)
(<Metabolite unagamu_c at 0x7f3b14142dd0>, True)
(<Metabolite 5prdmbz_c at 0x7f3b15a4a5d0>, False)
(<Metabolite cynt_e at 0x7f3b15a4a6d0>, False)
(<Metabolite cit_p at 0x7f3b15a3f890>, True)
(<Metabolite xan_p at 0x7f3b15a4a2d0>, True)
(<Metabolite fruur_p at 0x7f3b15a4a4d0>, False)
(<Metabolite ggptrc_c at 0x7f3b15a3fe90>, True)
(<Metabolite sulfac_e at 0x7f3b15a4a3d0>, False)
(<Metabolite ps160_c at 0x7f3b15a4a8d0>, True)
(<Metabolite pg120_c at 0x7f3b158dd6d0>, True)
(<Metabolite 2agpe141_p at 0x7f3b14142cd0>, True)
(<Metabolite apg140_c at 0x7f3b15a3fa90>, True)
(<Metabolite dhna_c at 0x7f3b15a4a7d0>, True)
(<Metabolite galctn__L_c at 0x7f3b15a4a9d0>, False)
(<Metabolite lipa_cold_e at 0x7f3b158c7b50>, True)
(<Metabolite bwcogdp_c at 0x7f3b15a4a1d0>, True)
(<Metabolite thptdn_c at 0x7f3b15a4aed0>, False)
(<Metabolite 6pgc_c at 0x7f3b15a3fd90>, True)
(<Metabolite udpgal_c at 0x7f3b15bd6310>, True)
(<Metabolite rml1p_c at 0x7f3b15bd6410>, True)
(<Metabolite cytd_c at 0x7f3b15bd6810>, True)
(<Metabolite thym_c at 0x7f3b15bd6210>, True)
(<Metabolite sbzcoa_c at 0x7f3b15bd6910>, True)
(<Metabolite gal_e at 0x7f3b07eea150>, False)
(<Metabolite acnam_c at 0x7f3b15a9e310>, False)
(<Metabolite dha_e at 0x7f3b15bd6b10>, True)
(<Metabolite aacald_c at 0x7f3b15a94e10>, False)
(<Metabolite gbbtn_p at 0x7f3b15a4aad0>, False)
(<Metabolite 4abut_p at 0x7f3b15bd6d10>, True)
(<Metabolite mnl_p at 0x7f3b15a3fc90>, False)
(<Metabolite 12ppd__R_c at 0x7f3b15a4add0>, True)
(<Metabolite dad_5_c at 0x7f3b15bf6350>, True)
(<Metabolite LalaDgluMdap_p at 0x7f3b15a3f190>, True)
(<Metabolite hhlipa_c at 0x7f3b15a4afd0>, True)
(<Metabolite crnDcoa_c at 0x7f3b15bf6250>, False)
(<Metabolite zn2_c at 0x7f3b14142e10>, True)
(<Metabolite skm_e at 0x7f3b14142f50>, False)
(<Metabolite 3odecACP_c at 0x7f3b15bf6650>, False)
(<Metabolite 1tdecg3p_c at 0x7f3b15bf6150>, True)
(<Metabolite pa140_c at 0x7f3b14142ed0>, True)
(<Metabolite cdpdtdec7eg_c at 0x7f3b14142b90>, True)
(<Metabolite 2agpe140_c at 0x7f3b15bd6c10>, True)
(<Metabolite teo2_c at 0x7f3b15bf6850>, False)
(<Metabolite 2aobut_c at 0x7f3b14142fd0>, True)
(<Metabolite 4r5au_c at 0x7f3b14142ad0>, True)
(<Metabolite gam_e at 0x7f3b15bf6750>, False)
(<Metabolite met__L_e at 0x7f3b15bf6950>, True)
(<Metabolite 4hbz_c at 0x7f3b159d1390>, True)
(<Metabolite dscl_c at 0x7f3b15bf6c50>, True)
(<Metabolite phthr_c at 0x7f3b15bd6f10>, True)
(<Metabolite acmana_e at 0x7f3b15bf6450>, False)
(<Metabolite n8aspmd_c at 0x7f3b15bf6d50>, True)
(<Metabolite ascb__L_e at 0x7f3b15bf6550>, False)
(<Metabolite thymd_p at 0x7f3b15bf6e50>, True)
(<Metabolite ditp_c at 0x7f3b159d1590>, True)
(<Metabolite 23dappa_e at 0x7f3b159d1190>, False)
(<Metabolite um4p_c at 0x7f3b15bd6710>, True)
(<Metabolite uLa4fn_c at 0x7f3b159d1c90>, True)
(<Metabolite lipa_p at 0x7f3b15a94310>, True)
(<Metabolite zn2_p at 0x7f3b159d1d90>, True)
(<Metabolite hg2_c at 0x7f3b159d21d0>, False)
(<Metabolite 2tpr3dpcoa_c at 0x7f3b159d1890>, True)
(<Metabolite bglycogen_c at 0x7f3b159d1e90>, True)
(<Metabolite dsbdox_c at 0x7f3b159d22d0>, False)
(<Metabolite progly_e at 0x7f3b159d25d0>, False)
(<Metabolite ogmeACP_c at 0x7f3b159d1f90>, False)
(<Metabolite hpmeACP_c at 0x7f3b159d24d0>, False)
(<Metabolite sufse_c at 0x7f3b07a94190>, False)
(<Metabolite cs1_p at 0x7f3b159d29d0>, False)
(<Metabolite rbl__L_c at 0x7f3b159d27d0>, False)
(<Metabolite indole_c at 0x7f3b159d1a90>, True)
(<Metabolite eig3p_c at 0x7f3b14142c50>, True)
(<Metabolite 26dap__M_c at 0x7f3b07a94050>, True)
(<Metabolite thf_c at 0x7f3b15bd6e10>, True)
(<Metabolite orot5p_c at 0x7f3b15bf6b50>, True)
(<Metabolite h_e at 0x7f3b159d2bd0>, True)
(<Metabolite aact_c at 0x7f3b159d1b90>, True)
(<Metabolite asn__L_e at 0x7f3b159d20d0>, True)
(<Metabolite 5caiz_c at 0x7f3b15781510>, True)
(<Metabolite dhnpt_c at 0x7f3b15781310>, True)
(<Metabolite pyam5p_c at 0x7f3b159d2ed0>, True)
(<Metabolite lcts_e at 0x7f3b159d1090>, False)
(<Metabolite btcoa_c at 0x7f3b15781410>, True)
(<Metabolite u3hga_c at 0x7f3b15781110>, True)
(<Metabolite tdcoa_c at 0x7f3b15781210>, True)
(<Metabolite dca_e at 0x7f3b159d2ad0>, False)
(<Metabolite malt6p_c at 0x7f3b15bd6610>, False)
(<Metabolite met__L_p at 0x7f3b07a942d0>, True)
(<Metabolite ser__L_p at 0x7f3b15781610>, True)
(<Metabolite octa_p at 0x7f3b158c7f50>, False)
(<Metabolite chtbs_e at 0x7f3b159d23d0>, False)
(<Metabolite dopa_e at 0x7f3b15781810>, False)
(<Metabolite isetac_e at 0x7f3b15798350>, False)
(<Metabolite cpgn_c at 0x7f3b15781f10>, False)
(<Metabolite butACP_c at 0x7f3b15781e10>, False)
(<Metabolite 1hdec9eg3p_c at 0x7f3b07a94150>, True)
(<Metabolite pe181_c at 0x7f3b15781b10>, True)
(<Metabolite 2agpg160_c at 0x7f3b15798150>, True)
(<Metabolite hxa_c at 0x7f3b15798750>, True)
(<Metabolite 3hppnl_c at 0x7f3b159d2cd0>, False)
(<Metabolite glyc2p_c at 0x7f3b15781910>, False)
(<Metabolite wco_c at 0x7f3b15bd6a10>, True)
(<Metabolite dhmpt_c at 0x7f3b15798b50>, True)
(<Metabolite mincyc_p at 0x7f3b15798550>, False)
(<Metabolite sq_c at 0x7f3b15798850>, False)
(<Metabolite sfp_c at 0x7f3b07a94290>, False)
(<Metabolite sq_e at 0x7f3b15798250>, False)
(<Metabolite 5phdt_c at 0x7f3b15798050>, False)
(<Metabolite adpglc_c at 0x7f3b07a94210>, True)
(<Metabolite dudp_c at 0x7f3b15798650>, True)
(<Metabolite 4ppan_c at 0x7f3b157af390>, True)
(<Metabolite 23dhb_c at 0x7f3b15798f50>, True)
(<Metabolite 2mecdp_c at 0x7f3b157af190>, True)
(<Metabolite dcyt_e at 0x7f3b159d2dd0>, False)
(<Metabolite orot_e at 0x7f3b157af490>, False)
(<Metabolite agdpcbi_c at 0x7f3b157af990>, False)
(<Metabolite u3aga_c at 0x7f3b15781d10>, True)
(<Metabolite thm_c at 0x7f3b07a940d0>, False)
(<Metabolite feoxam_c at 0x7f3b157afa90>, False)
(<Metabolite gln__L_p at 0x7f3b15bf6f50>, False)
(<Metabolite glyc_p at 0x7f3b07a94390>, True)
(<Metabolite thr__L_p at 0x7f3b157af690>, True)
(<Metabolite ttdca_p at 0x7f3b157af790>, True)
(<Metabolite acgam_c at 0x7f3b15798450>, True)
(<Metabolite metsox_S__L_p at 0x7f3b15bf6a50>, False)
(<Metabolite pacald_p at 0x7f3b15b940d0>, False)
(<Metabolite eca4colipa_p at 0x7f3b15b941d0>, True)
(<Metabolite udpglcur_e at 0x7f3b157af890>, False)
(<Metabolite murein3px3p_p at 0x7f3b15b944d0>, True)
(<Metabolite 3hcpalm9eACP_c at 0x7f3b15b943d0>, False)
(<Metabolite 3ocpalm9eACP_c at 0x7f3b157afc90>, False)
(<Metabolite 2ddecg3p_c at 0x7f3b15b946d0>, True)
(<Metabolite 1agpe161_p at 0x7f3b07a94350>, True)
(<Metabolite ppa_p at 0x7f3b15b949d0>, False)
(<Metabolite msa_c at 0x7f3b15b948d0>, True)
(<Metabolite slnt_c at 0x7f3b15798a50>, True)
(<Metabolite metglcur_e at 0x7f3b15b94bd0>, False)
(<Metabolite dgsn_c at 0x7f3b15b94fd0>, True)
(<Metabolite but_c at 0x7f3b159d26d0>, False)
(<Metabolite glutrna_c at 0x7f3b15b86110>, False)
(<Metabolite adn_e at 0x7f3b15b942d0>, True)
(<Metabolite octdp_c at 0x7f3b15b86310>, True)
(<Metabolite cinnm_c at 0x7f3b157af590>, False)
(<Metabolite arbt6p_c at 0x7f3b15b94cd0>, False)
(<Metabolite ttdca_c at 0x7f3b15798c50>, True)
(<Metabolite tma_p at 0x7f3b15b86710>, False)
(<Metabolite fe3dcit_e at 0x7f3b15b86a10>, True)
(<Metabolite fe3hox_un_c at 0x7f3b15b945d0>, False)
(<Metabolite damp_e at 0x7f3b15b86210>, False)
(<Metabolite o16a4und_p at 0x7f3b15b86e10>, False)
(<Metabolite n2o_c at 0x7f3b15b86510>, False)
(<Metabolite hg2_e at 0x7f3b15b86810>, False)
(<Metabolite 3hoctACP_c at 0x7f3b15b86c10>, False)
(<Metabolite toctd2eACP_c at 0x7f3b159d1790>, False)
(<Metabolite dsbcox_p at 0x7f3b157afe90>, False)
(<Metabolite clpn160_p at 0x7f3b15b77050>, True)
(<Metabolite clpn181_p at 0x7f3b157af090>, True)
(<Metabolite arbt_p at 0x7f3b15b77350>, False)
(<Metabolite ttdceap_c at 0x7f3b15b77150>, True)
(<Metabolite cpmp_c at 0x7f3b15b77450>, True)
(<Metabolite doxrbcn_e at 0x7f3b15b77550>, False)
(<Metabolite dxylnt_p at 0x7f3b15b86610>, False)
(<Metabolite 2hptcoa_c at 0x7f3b15b94ad0>, False)
(<Metabolite ru5p__D_c at 0x7f3b15b77750>, True)
(<Metabolite 23dhmb_c at 0x7f3b15b86d10>, True)
(<Metabolite galur_c at 0x7f3b15b77a50>, False)
(<Metabolite arab__L_e at 0x7f3b15b77250>, False)
(<Metabolite lald__L_c at 0x7f3b15b77d50>, True)
(<Metabolite 6hmhpt_c at 0x7f3b07a94510>, True)
(<Metabolite ppcoa_c at 0x7f3b15b77850>, True)
(<Metabolite adocbi_c at 0x7f3b07a94250>, False)
(<Metabolite acac_c at 0x7f3b15b77950>, False)
(<Metabolite acmanap_c at 0x7f3b15b39290>, True)
(<Metabolite pppn_e at 0x7f3b15b77650>, False)
(<Metabolite 3hcinnm_e at 0x7f3b15b39390>, False)
(<Metabolite tmao_c at 0x7f3b15b77e50>, False)
(<Metabolite tsul_c at 0x7f3b15b39590>, False)
(<Metabolite man6pglyc_c at 0x7f3b15b39790>, False)
(<Metabolite oxam_c at 0x7f3b15b39490>, True)
(<Metabolite dha_p at 0x7f3b157aff90>, True)
(<Metabolite LalaDgluMdapDala_c at 0x7f3b15b39690>, True)
(<Metabolite colipa_p at 0x7f3b15b39190>, True)
(<Metabolite colipa_e at 0x7f3b15b39890>, True)
(<Metabolite glyc2p_p at 0x7f3b07a94610>, False)
(<Metabolite pe141_p at 0x7f3b15b39f90>, True)
(<Metabolite 12dgr140_p at 0x7f3b15b77c50>, True)
(<Metabolite 2hdecg3p_p at 0x7f3b15b86910>, True)
(<Metabolite oxadpcoa_c at 0x7f3b15b5e1d0>, False)
(<Metabolite mptamp_c at 0x7f3b15b39e90>, True)
(<Metabolite cs1_e at 0x7f3b15b5e4d0>, False)
(<Metabolite glc__D_c at 0x7f3b15b39b90>, True)
(<Metabolite e4p_c at 0x7f3b15b39990>, True)
(<Metabolite man1p_c at 0x7f3b15b5e2d0>, True)
(<Metabolite acser_c at 0x7f3b157afb90>, True)
(<Metabolite 2shchc_c at 0x7f3b15b5e5d0>, True)
(<Metabolite dxyl5p_c at 0x7f3b15b5e7d0>, True)
(<Metabolite man_e at 0x7f3b15b5e6d0>, False)
(<Metabolite acmana_c at 0x7f3b15b5e3d0>, False)
(<Metabolite fcl__L_c at 0x7f3b15b5ebd0>, False)
(<Metabolite h2_e at 0x7f3b15b5eed0>, False)
(<Metabolite nmn_e at 0x7f3b07a946d0>, False)
(<Metabolite man6p_e at 0x7f3b15b39d90>, False)
(<Metabolite csn_p at 0x7f3b15b5e9d0>, False)
(<Metabolite cytd_p at 0x7f3b15b77f50>, True)
(<Metabolite fuc__L_p at 0x7f3b15710410>, False)
(<Metabolite mal__L_p at 0x7f3b15710510>, True)
(<Metabolite tmao_p at 0x7f3b15710210>, False)
(<Metabolite hxa_p at 0x7f3b15b5ecd0>, True)
(<Metabolite mobd_p at 0x7f3b15b5e8d0>, True)
(<Metabolite g1p_p at 0x7f3b15710610>, False)
(<Metabolite anhgm3p_c at 0x7f3b15b39090>, True)
(<Metabolite ggagicolipa_c at 0x7f3b15710310>, True)
(<Metabolite pser__L_p at 0x7f3b15710910>, False)
(<Metabolite fe3dhbzs_p at 0x7f3b15710110>, False)
(<Metabolite cu_e at 0x7f3b15710a10>, False)
(<Metabolite cdpdtdecg_c at 0x7f3b07a94110>, True)
(<Metabolite pe120_c at 0x7f3b15710d10>, True)
(<Metabolite pa120_p at 0x7f3b07a94650>, True)
(<Metabolite ddcap_c at 0x7f3b15710810>, True)
(<Metabolite hdcap_c at 0x7f3b15b5edd0>, True)
(<Metabolite egmeACP_c at 0x7f3b15710e10>, False)
(<Metabolite cph4_c at 0x7f3b15710710>, True)
(<Metabolite iscu_2fe2s2_c at 0x7f3b15727450>, False)
(<Metabolite thmnp_c at 0x7f3b15b5efd0>, True)
(<Metabolite trdox_c at 0x7f3b15727150>, False)
(<Metabolite 5mtr_c at 0x7f3b15727050>, True)
(<Metabolite 3ig3p_c at 0x7f3b15710f10>, True)
(<Metabolite sl26da_c at 0x7f3b15727850>, True)
(<Metabolite din_c at 0x7f3b15727750>, True)
(<Metabolite ichor_c at 0x7f3b15727650>, True)
(<Metabolite cpppg3_c at 0x7f3b15727350>, True)
(<Metabolite 3ohcoa_c at 0x7f3b15727950>, True)
(<Metabolite ser__D_e at 0x7f3b15b39c90>, False)
(<Metabolite ohpb_c at 0x7f3b15727a50>, True)
(<Metabolite amp_e at 0x7f3b15710c10>, False)
(<Metabolite o2s_c at 0x7f3b15727550>, True)
(<Metabolite ugmd_c at 0x7f3b15c68390>, True)
(<Metabolite fecrm_c at 0x7f3b15b5ead0>, False)
(<Metabolite ile__L_p at 0x7f3b15b77b50>, True)
(<Metabolite nmn_p at 0x7f3b15c68090>, False)
(<Metabolite hxan_p at 0x7f3b15727e50>, True)
(<Metabolite metsox_R__L_p at 0x7f3b15c68690>, False)
(<Metabolite 23cgmp_p at 0x7f3b15c68490>, False)
(<Metabolite LalaDgluMdap_e at 0x7f3b15c68990>, True)
(<Metabolite cgly_p at 0x7f3b15c68190>, True)
(<Metabolite 2hdecg3p_c at 0x7f3b15c68890>, True)
(<Metabolite 1agpg160_p at 0x7f3b15c68290>, True)
(<Metabolite 4abzglu_p at 0x7f3b07a94550>, True)
(<Metabolite 34dhpha_c at 0x7f3b15727c50>, False)
(<Metabolite glcn_c at 0x7f3b15c68d90>, True)
(<Metabolite paps_c at 0x7f3b15c9f2d0>, True)
(<Metabolite dhor__S_c at 0x7f3b15c68b90>, True)
(<Metabolite adn_c at 0x7f3b15c68a90>, True)
(<Metabolite 2me4p_c at 0x7f3b15727d50>, True)
(<Metabolite tre_c at 0x7f3b15c68c90>, True)
(<Metabolite dad_2_e at 0x7f3b15c9f3d0>, False)
(<Metabolite thym_e at 0x7f3b15c68e90>, True)
(<Metabolite fecrm_p at 0x7f3b15c9f5d0>, False)
(<Metabolite ins_p at 0x7f3b15c9f6d0>, True)
(<Metabolite k_c at 0x7f3b15c9f7d0>, True)
(<Metabolite o2_p at 0x7f3b15c9fbd0>, True)
(<Metabolite ala_B_p at 0x7f3b15b39a90>, False)
(<Metabolite cbi_e at 0x7f3b15c9f4d0>, False)
(<Metabolite tungs_p at 0x7f3b15c9fad0>, True)
(<Metabolite dtmp_e at 0x7f3b15c9f8d0>, False)
(<Metabolite 12dgr160_c at 0x7f3b1595e110>, True)
(<Metabolite 12dgr181_c at 0x7f3b15c9f9d0>, True)
(<Metabolite dsbcrd_p at 0x7f3b1595e310>, False)
(<Metabolite pgp181_p at 0x7f3b15798e50>, True)
(<Metabolite orot_p at 0x7f3b1595e210>, False)
(<Metabolite LalaDglu_p at 0x7f3b1595e410>, False)
(<Metabolite cdigmp_c at 0x7f3b15c9ffd0>, True)
(<Metabolite uri_c at 0x7f3b15c9fdd0>, True)
(<Metabolite dad_2_c at 0x7f3b1595e810>, True)
(<Metabolite 3hhcoa_c at 0x7f3b15c68f90>, True)
(<Metabolite 3otdcoa_c at 0x7f3b07a94750>, True)
(<Metabolite 3hhdcoa_c at 0x7f3b1595e710>, True)
(<Metabolite hx2coa_c at 0x7f3b07a94910>, True)
(<Metabolite uacmam_c at 0x7f3b1595ea10>, True)
(<Metabolite glycogen_c at 0x7f3b1595ef10>, True)
(<Metabolite ahcys_c at 0x7f3b07a948d0>, True)
(<Metabolite pydx_c at 0x7f3b15c68590>, True)
(<Metabolite lac__D_e at 0x7f3b1589b250>, True)
(<Metabolite 2mcacn_c at 0x7f3b1589b150>, True)
(<Metabolite aconm_c at 0x7f3b1595e510>, True)
(<Metabolite adn_p at 0x7f3b15c9fed0>, True)
(<Metabolite asn__L_p at 0x7f3b1595ec10>, True)
(<Metabolite dgsn_p at 0x7f3b1589b450>, False)
(<Metabolite manglyc_p at 0x7f3b07a94850>, False)
(<Metabolite dms_p at 0x7f3b1595e910>, False)
(<Metabolite h2s_p at 0x7f3b1589b850>, True)
(<Metabolite feoxam_e at 0x7f3b1589b650>, False)
(<Metabolite lipoate_e at 0x7f3b1589b750>, False)
(<Metabolite pacald_c at 0x7f3b1589bb50>, False)
(<Metabolite isetac_c at 0x7f3b1589b950>, False)
(<Metabolite anhgm4p_c at 0x7f3b07a94a50>, True)
(<Metabolite gggagicolipa_c at 0x7f3b1589bf50>, True)
(<Metabolite grxrd_c at 0x7f3b07a94b50>, False)
(<Metabolite so2_e at 0x7f3b15727250>, False)
(<Metabolite cys__D_c at 0x7f3b1589ba50>, False)
(<Metabolite pa161_c at 0x7f3b15884590>, True)
(<Metabolite pgp140_c at 0x7f3b15884490>, True)
(<Metabolite pgp161_c at 0x7f3b1595ee10>, True)
(<Metabolite ps180_c at 0x7f3b15884090>, True)
(<Metabolite pe141_c at 0x7f3b15c9fcd0>, True)
(<Metabolite cpg160_c at 0x7f3b15884690>, True)
(<Metabolite crn__D_e at 0x7f3b15884890>, False)
(<Metabolite 13ppd_c at 0x7f3b15884990>, False)
(<Metabolite pran_c at 0x7f3b1595ed10>, True)
(<Metabolite gsn_c at 0x7f3b15884a90>, True)
(<Metabolite ins_c at 0x7f3b15884d90>, True)
(<Metabolite ura_c at 0x7f3b158fc0d0>, True)
(<Metabolite chol_e at 0x7f3b07a94b90>, False)
(<Metabolite gly_e at 0x7f3b15884b90>, True)
(<Metabolite 8aonn_c at 0x7f3b1589be50>, True)
(<Metabolite pdx5p_c at 0x7f3b07a94a10>, True)
(<Metabolite 23doguln_c at 0x7f3b15884390>, False)
(<Metabolite tmao_e at 0x7f3b15c9f1d0>, False)
(<Metabolite acac_p at 0x7f3b158fc5d0>, False)
(<Metabolite but_p at 0x7f3b15884190>, False)
(<Metabolite 34dhpac_p at 0x7f3b158fc7d0>, False)
(<Metabolite lipa_e at 0x7f3b158fc4d0>, True)
(<Metabolite enlipa_e at 0x7f3b15884e90>, True)
(<Metabolite n2o_e at 0x7f3b158fc6d0>, False)
(<Metabolite cobalt2_c at 0x7f3b158fccd0>, True)
(<Metabolite cobalt2_p at 0x7f3b158fcad0>, True)
(<Metabolite mmet_p at 0x7f3b158fcbd0>, False)
(<Metabolite aso3_e at 0x7f3b07a949d0>, False)
(<Metabolite dsbgox_p at 0x7f3b158fc9d0>, False)
(<Metabolite pg140_p at 0x7f3b1568c110>, True)
(<Metabolite 2agpg181_c at 0x7f3b1589b350>, True)
(<Metabolite apg120_c at 0x7f3b158fc3d0>, True)
(<Metabolite apg160_c at 0x7f3b158fc8d0>, True)
(<Metabolite mchtbs6p_c at 0x7f3b1568c410>, False)
(<Metabolite fdp_c at 0x7f3b1568c810>, True)
(<Metabolite mthgxl_c at 0x7f3b158fc1d0>, True)
(<Metabolite rmn_c at 0x7f3b1568ca10>, False)
(<Metabolite dtmp_c at 0x7f3b1568c310>, True)
(<Metabolite gdp_c at 0x7f3b15884c90>, True)
(<Metabolite man_c at 0x7f3b1568c610>, True)
(<Metabolite uaagmda_c at 0x7f3b1568c910>, True)
(<Metabolite crn_e at 0x7f3b1568cd10>, False)
(<Metabolite fe2_c at 0x7f3b1568cc10>, True)
(<Metabolite thm_e at 0x7f3b15c0c250>, False)
(<Metabolite glyald_e at 0x7f3b1568cb10>, True)
(<Metabolite indole_e at 0x7f3b15b94dd0>, True)
(<Metabolite mg2_e at 0x7f3b1568c710>, True)
(<Metabolite S2hglut_c at 0x7f3b1568cf10>, True)
(<Metabolite glyclt_p at 0x7f3b15c0c150>, True)
(<Metabolite xtsn_p at 0x7f3b15c0c350>, True)
(<Metabolite akg_p at 0x7f3b158fcfd0>, True)
(<Metabolite frulys_c at 0x7f3b158fced0>, False)
(<Metabolite g3pg_e at 0x7f3b07a94ad0>, True)
(<Metabolite ocACP_c at 0x7f3b15c0c950>, False)
(<Metabolite ttdcea_p at 0x7f3b15c0c650>, True)
(<Metabolite 2agpe160_c at 0x7f3b1568c510>, True)
(<Metabolite kdo2lipid4_p at 0x7f3b15c0ca50>, True)
(<Metabolite athtp_c at 0x7f3b15c0c850>, True)
(<Metabolite 3ohodcoa_c at 0x7f3b15c0cd50>, True)
(<Metabolite 23dhbzs3_c at 0x7f3b15c0cc50>, True)
(<Metabolite sqg_c at 0x7f3b07a94dd0>, False)
(<Metabolite fad_p at 0x7f3b140d6190>, True)
(<Metabolite rhmn_c at 0x7f3b15884f90>, True)
(<Metabolite cbp_c at 0x7f3b15c0c050>, True)
(<Metabolite 3mob_c at 0x7f3b15c0cb50>, True)
(<Metabolite suchms_c at 0x7f3b140d6690>, True)
(<Metabolite dcyt_c at 0x7f3b140d6390>, True)
(<Metabolite dc2coa_c at 0x7f3b140d6590>, True)
(<Metabolite glyc_e at 0x7f3b15c0c450>, True)
(<Metabolite 4mop_c at 0x7f3b140d6990>, True)
(<Metabolite gal1p_c at 0x7f3b140d6790>, True)
(<Metabolite dann_c at 0x7f3b140d6490>, True)
(<Metabolite gdpmann_c at 0x7f3b140d6a90>, True)
(<Metabolite 2h3oppan_c at 0x7f3b140d6b90>, True)
(<Metabolite hpyr_c at 0x7f3b1568ce10>, True)
(<Metabolite tartr__L_e at 0x7f3b07a94690>, False)
(<Metabolite cbi_c at 0x7f3b140d6d90>, False)
(<Metabolite octa_e at 0x7f3b140d6c90>, False)
(<Metabolite gdp_e at 0x7f3b07a94c50>, False)
(<Metabolite dmso_p at 0x7f3b15c0cf50>, False)
(<Metabolite gdp_p at 0x7f3b1561e6d0>, False)
(<Metabolite 4hoxpacd_e at 0x7f3b1561e0d0>, False)
(<Metabolite acser_p at 0x7f3b140d6890>, True)
(<Metabolite cdpdodecg_c at 0x7f3b140d6290>, True)
(<Metabolite ps140_c at 0x7f3b1561e3d0>, True)
(<Metabolite 2tdecg3p_c at 0x7f3b1561e5d0>, True)
(<Metabolite 2tdec7eg3p_c at 0x7f3b15727f50>, True)
(<Metabolite bmocogdp_c at 0x7f3b1561ead0>, True)
(<Metabolite mththf_e at 0x7f3b1561ebd0>, True)
(<Metabolite dhptdp_c at 0x7f3b1561e8d0>, True)
(<Metabolite cholate_c at 0x7f3b1561e7d0>, False)
(<Metabolite puacgam_c at 0x7f3b1561ecd0>, True)
(<Metabolite fum_c at 0x7f3b15611110>, True)
(<Metabolite spmd_c at 0x7f3b07a94d50>, True)
(<Metabolite 3dhq_c at 0x7f3b1561edd0>, True)
(<Metabolite hisp_c at 0x7f3b15611610>, True)
(<Metabolite so4_e at 0x7f3b140d6090>, True)
(<Metabolite orn_e at 0x7f3b1561eed0>, True)
(<Metabolite galt1p_c at 0x7f3b1561e2d0>, False)
(<Metabolite ppa_c at 0x7f3b15611710>, True)
(<Metabolite taur_c at 0x7f3b1561e9d0>, False)
(<Metabolite uamag_c at 0x7f3b140d6e90>, True)
(<Metabolite dhpt_c at 0x7f3b158fc2d0>, True)
(<Metabolite manglyc_e at 0x7f3b60e14090>, False)
(<Metabolite ascb__L_p at 0x7f3b15611b10>, False)
(<Metabolite idon__L_p at 0x7f3b1561e4d0>, True)
(<Metabolite urea_p at 0x7f3b156eb150>, True)
(<Metabolite gicolipa_c at 0x7f3b15611f10>, True)
(<Metabolite halipa_e at 0x7f3b07a94e50>, False)
(<Metabolite butso3_c at 0x7f3b1561efd0>, False)
(<Metabolite lipoate_p at 0x7f3b07a94ed0>, False)
(<Metabolite 2agpg120_p at 0x7f3b15611d10>, True)
(<Metabolite 2agpg180_p at 0x7f3b156eb050>, True)
(<Metabolite 1agpe120_p at 0x7f3b15611910>, True)
(<Metabolite oxa_c at 0x7f3b156eb750>, False)
(<Metabolite dxylnt_e at 0x7f3b156eba50>, False)
(<Metabolite nalme_c at 0x7f3b15611e10>, False)
(<Metabolite udpg_c at 0x7f3b156ebb50>, True)
(<Metabolite 3c3hmp_c at 0x7f3b156eb650>, True)
(<Metabolite anth_c at 0x7f3b156eb850>, True)
(<Metabolite pap_c at 0x7f3b07a94a90>, True)
(<Metabolite xmp_c at 0x7f3b15611210>, True)
(<Metabolite ile__L_e at 0x7f3b156ebf50>, True)
(<Metabolite 2omhmbl_c at 0x7f3b159d1990>, True)
(<Metabolite 5dh4dglc_c at 0x7f3b156eb950>, False)
(<Metabolite cechddd_c at 0x7f3b07a94d90>, False)
(<Metabolite 25dkglcn_c at 0x7f3b156ebd50>, False)
(<Metabolite adphep_DD_c at 0x7f3b15611c10>, True)
(<Metabolite h2s_e at 0x7f3b15cc6590>, True)
(<Metabolite acac_e at 0x7f3b156eb250>, False)
(<Metabolite 4adcho_c at 0x7f3b15cc6790>, True)
(<Metabolite rib__D_p at 0x7f3b15611410>, False)
(<Metabolite xyl__D_p at 0x7f3b15cc6690>, False)
(<Metabolite inost_p at 0x7f3b156eb350>, False)
(<Metabolite ocdca_p at 0x7f3b1561e1d0>, True)
(<Metabolite g3ps_e at 0x7f3b15cc6090>, False)
(<Metabolite 3gmp_p at 0x7f3b15cc6e90>, False)
(<Metabolite anhgm4p_p at 0x7f3b15d321d0>, True)
(<Metabolite udpLa4n_c at 0x7f3b15cc6b90>, True)
(<Metabolite hacolipa_e at 0x7f3b15cc6190>, False)
(<Metabolite o16aund_c at 0x7f3b14142f10>, False)
(<Metabolite o16aund_p at 0x7f3b156eb550>, False)
(<Metabolite 3hhexACP_c at 0x7f3b07a94f10>, False)
(<Metabolite t3c5ddeceACP_c at 0x7f3b15d320d0>, False)
(<Metabolite ps120_c at 0x7f3b15cc6290>, True)
(<Metabolite 12dgr161_p at 0x7f3b15cc6990>, True)
(<Metabolite 12dgr120_p at 0x7f3b15cc6f90>, True)
(<Metabolite pydam_p at 0x7f3b15d328d0>, False)
(<Metabolite btn_p at 0x7f3b15d326d0>, False)
(<Metabolite ttdcap_c at 0x7f3b15d32dd0>, True)
(<Metabolite ch4_p at 0x7f3b15d32cd0>, False)
(<Metabolite fmn_p at 0x7f3b15d32ad0>, True)
(<Metabolite dhptdd_c at 0x7f3b15d32bd0>, True)
(<Metabolite dtgcl_c at 0x7f3b15611310>, False)
(<Metabolite cholate_p at 0x7f3b156ebe50>, False)
(<Metabolite 34dphacoa_c at 0x7f3b07a94bd0>, False)
(<Metabolite metglcur_p at 0x7f3b15d325d0>, False)
(<Metabolite g1p_c at 0x7f3b07fc3410>, True)
(<Metabolite acorn_c at 0x7f3b1589bd50>, True)
(<Metabolite glu5sa_c at 0x7f3b07a94f90>, True)
(<Metabolite 2dhp_c at 0x7f3b15d32fd0>, True)
(<Metabolite aacoa_c at 0x7f3b07fc3710>, True)
(<Metabolite hemeO_c at 0x7f3b15cc6490>, True)
(<Metabolite 4abut_e at 0x7f3b1568c210>, True)
(<Metabolite glu__L_e at 0x7f3b15d323d0>, True)
(<Metabolite 2oph_c at 0x7f3b07fc3910>, True)
(<Metabolite ckdo_c at 0x7f3b15d324d0>, True)
(<Metabolite glcr_c at 0x7f3b15cc6a90>, False)
(<Metabolite gmhep7p_c at 0x7f3b07fc3a10>, True)
(<Metabolite od2coa_c at 0x7f3b07fc3b10>, True)
(<Metabolite agm_p at 0x7f3b07a94f50>, True)
(<Metabolite chol_p at 0x7f3b15611810>, False)
(<Metabolite 3hpppn_p at 0x7f3b15d322d0>, False)
(<Metabolite minohp_p at 0x7f3b07fc3810>, False)
(<Metabolite dcmp_p at 0x7f3b07fc3610>, False)
(<Metabolite eca3und_p at 0x7f3b07fc3310>, True)
(<Metabolite ragund_c at 0x7f3b07a94e90>, False)
(<Metabolite no_p at 0x7f3b07fc3c10>, False)
(<Metabolite murein4p4p_p at 0x7f3b07fc3210>, True)
(<Metabolite tpalm2eACP_c at 0x7f3b07ffd150>, False)
(<Metabolite pgp160_c at 0x7f3b07ffd750>, True)
(<Metabolite pe160_c at 0x7f3b07ffdb50>, True)
(<Metabolite enlipa_p at 0x7f3b07ffd250>, True)
(<Metabolite thcur_c at 0x7f3b07ffdf50>, False)
(<Metabolite nadhx__R_c at 0x7f3b07ffd850>, True)
(<Metabolite 2cpr5p_c at 0x7f3b15844090>, True)
(<Metabolite dcmp_c at 0x7f3b07ffdd50>, True)
(<Metabolite dgmp_c at 0x7f3b07f81050>, True)
(<Metabolite 4mhetz_c at 0x7f3b07fc3f10>, False)
(<Metabolite tyr__L_e at 0x7f3b07fc3510>, True)
(<Metabolite 2dmmq8_c at 0x7f3b15d32ed0>, True)
(<Metabolite cys__L_e at 0x7f3b15cc6890>, True)
(<Metabolite 26dap__M_e at 0x7f3b15844790>, False)
(<Metabolite pppn_c at 0x7f3b07ffd450>, False)
(<Metabolite malthx_c at 0x7f3b07ffd650>, False)
(<Metabolite acon_T_c at 0x7f3b15844590>, True)
(<Metabolite bbtcoa_c at 0x7f3b15844890>, False)
(<Metabolite ddca_e at 0x7f3b07ffda50>, False)
(<Metabolite octeACP_c at 0x7f3b15844b90>, False)
(<Metabolite gtspmd_c at 0x7f3b15844e90>, True)
(<Metabolite cys__L_p at 0x7f3b15844390>, True)
(<Metabolite arbtn_fe3_p at 0x7f3b07ffd550>, False)
(<Metabolite orn_p at 0x7f3b15844690>, True)
(<Metabolite asp__L_p at 0x7f3b15844d90>, True)
(<Metabolite crn_p at 0x7f3b159a71d0>, False)
(<Metabolite pro__L_p at 0x7f3b15cc6390>, True)
(<Metabolite co2_p at 0x7f3b159a74d0>, True)
(<Metabolite fe3_c at 0x7f3b15844f90>, True)
(<Metabolite fad_e at 0x7f3b07ffd050>, True)
(<Metabolite 23dappa_c at 0x7f3b15844c90>, False)
(<Metabolite dopa_p at 0x7f3b159a73d0>, False)
(<Metabolite g3pc_p at 0x7f3b15844290>, False)
(<Metabolite anhgm3p_p at 0x7f3b159a77d0>, True)
(<Metabolite anhm4p_c at 0x7f3b159a7ed0>, True)
(<Metabolite udcpp_p at 0x7f3b159a79d0>, True)
(<Metabolite mg2_p at 0x7f3b159a78d0>, True)
(<Metabolite cyan_p at 0x7f3b156ebc50>, False)
(<Metabolite mercppyr_c at 0x7f3b159a7bd0>, True)
(<Metabolite udpg_p at 0x7f3b159a75d0>, False)
(<Metabolite fe3dhbzs_e at 0x7f3b159a7dd0>, False)
(<Metabolite t3c7mrseACP_c at 0x7f3b07f81250>, False)
(<Metabolite t3c11vaceACP_c at 0x7f3b159a7cd0>, False)
(<Metabolite pg180_c at 0x7f3b15978210>, True)
(<Metabolite 1agpe160_p at 0x7f3b15978410>, True)
(<Metabolite chtbs6p_c at 0x7f3b159a7fd0>, False)
(<Metabolite quin_p at 0x7f3b15844a90>, False)
(<Metabolite slnt_e at 0x7f3b159a76d0>, True)
(<Metabolite moadcoo_c at 0x7f3b15978910>, False)
(<Metabolite f_c at 0x7f3b159a7ad0>, False)
(<Metabolite 3c2hmp_c at 0x7f3b159a72d0>, True)
(<Metabolite pser__L_c at 0x7f3b15978d10>, True)
(<Metabolite 4abut_c at 0x7f3b15978b10>, True)
(<Metabolite gmp_c at 0x7f3b15978e10>, True)
(<Metabolite gua_c at 0x7f3b15978c10>, True)
(<Metabolite udcpdp_c at 0x7f3b14200350>, True)
(<Metabolite glu__D_c at 0x7f3b15978a10>, True)
(<Metabolite 3ophb_c at 0x7f3b07ffd350>, True)
(<Metabolite 3dhsk_c at 0x7f3b14200450>, True)
(<Metabolite acACP_c at 0x7f3b07ffdc50>, False)
(<Metabolite udpgalfur_c at 0x7f3b159a70d0>, True)
(<Metabolite feenter_p at 0x7f3b14200050>, True)
(<Metabolite glcr_p at 0x7f3b15844190>, False)
(<Metabolite tre_p at 0x7f3b14200a50>, False)
(<Metabolite imp_e at 0x7f3b14200250>, False)
(<Metabolite feoxam_un_p at 0x7f3b15978610>, False)
(<Metabolite gal1p_e at 0x7f3b14200950>, False)
(<Metabolite LalaDglu_c at 0x7f3b15978510>, True)
(<Metabolite acglc__D_c at 0x7f3b14200c50>, True)
(<Metabolite r5p_p at 0x7f3b14200d50>, False)
(<Metabolite r5p_e at 0x7f3b15978810>, False)
(<Metabolite acser_e at 0x7f3b14200b50>, True)
(<Metabolite mn2_p at 0x7f3b142f8390>, True)
(<Metabolite 3hpalmACP_c at 0x7f3b14200850>, False)
(<Metabolite 12dgr140_c at 0x7f3b07ffde50>, True)
(<Metabolite apg161_c at 0x7f3b15978710>, True)
(<Metabolite tartr__D_e at 0x7f3b14200750>, False)
(<Metabolite r2hglut_c at 0x7f3b14200150>, True)
(<Metabolite 5phua_c at 0x7f3b14200e50>, False)
(<Metabolite uppg3_c at 0x7f3b142f8490>, True)
(<Metabolite 3hocoa_c at 0x7f3b142f8190>, True)
(<Metabolite uagmda_c at 0x7f3b07f81190>, True)
(<Metabolite his__L_e at 0x7f3b142f8790>, True)
(<Metabolite hxan_e at 0x7f3b07f81090>, True)
(<Metabolite na1_e at 0x7f3b15978f10>, True)
(<Metabolite fmn_e at 0x7f3b142f8990>, True)
(<Metabolite glyc3p_e at 0x7f3b142f8d90>, True)
(<Metabolite 3hcinnm_c at 0x7f3b1430a1d0>, False)
(<Metabolite dtdp4aaddg_c at 0x7f3b142f8c90>, True)
(<Metabolite maltpt_c at 0x7f3b142f8890>, False)
(<Metabolite maltttr_c at 0x7f3b1430a6d0>, False)
(<Metabolite duri_p at 0x7f3b14200f50>, False)
(<Metabolite tartr__L_p at 0x7f3b142f8a90>, False)
(<Metabolite 26dap__M_p at 0x7f3b142f8290>, False)
(<Metabolite adocbl_p at 0x7f3b1430a2d0>, False)
(<Metabolite acolipa_p at 0x7f3b1430a0d0>, True)
(<Metabolite butso3_p at 0x7f3b1430a7d0>, False)
(<Metabolite cpgn_un_c at 0x7f3b07a94fd0>, False)
(<Metabolite ps161_c at 0x7f3b1430a3d0>, True)
(<Metabolite progly_p at 0x7f3b1430aad0>, False)
(<Metabolite pa181_p at 0x7f3b1430afd0>, True)
(<Metabolite 2agpe160_p at 0x7f3b1430aed0>, True)
(<Metabolite 2agpg140_c at 0x7f3b1430add0>, True)
(<Metabolite 1hdecg3p_p at 0x7f3b155b8110>, True)
(<Metabolite mal__D_p at 0x7f3b155b8310>, False)
(<Metabolite 5dglcn_p at 0x7f3b155b8610>, True)
(<Metabolite arbt_e at 0x7f3b07f81350>, False)
(<Metabolite quin_c at 0x7f3b155b8510>, False)
(<Metabolite sel_p at 0x7f3b14200650>, True)
(<Metabolite epmeACP_c at 0x7f3b142f8690>, False)
(<Metabolite mococdp_c at 0x7f3b155b8410>, True)
(<Metabolite doxrbcn_p at 0x7f3b142f8590>, False)
(<Metabolite hco3_c at 0x7f3b155b8810>, True)
(<Metabolite 15dap_c at 0x7f3b142f8e90>, True)
(<Metabolite ser__D_c at 0x7f3b155b8c10>, True)
(<Metabolite mlthf_c at 0x7f3b155b8d10>, True)
(<Metabolite frdp_c at 0x7f3b155c9150>, True)
(<Metabolite pant__R_c at 0x7f3b155b8a10>, True)
(<Metabolite glcur_c at 0x7f3b155b8710>, False)
(<Metabolite inost_e at 0x7f3b142f8090>, False)
(<Metabolite cytd_e at 0x7f3b155c9250>, True)
(<Metabolite 2dmmql8_c at 0x7f3b07f81310>, True)
(<Metabolite g3pe_c at 0x7f3b155b8210>, True)
(<Metabolite glyclt_e at 0x7f3b155b8f10>, True)
(<Metabolite 12ppd__S_e at 0x7f3b155c9950>, True)
(<Metabolite 1pyr5c_c at 0x7f3b155b8e10>, True)
(<Metabolite ppa_e at 0x7f3b155c9450>, False)
(<Metabolite acmum_p at 0x7f3b155b8910>, False)
(<Metabolite malttr_p at 0x7f3b155c9050>, False)
(<Metabolite acald_p at 0x7f3b155c9650>, True)
(<Metabolite gly_p at 0x7f3b155c9750>, True)
(<Metabolite ser__D_p at 0x7f3b155c9a50>, False)
(<Metabolite o2s_p at 0x7f3b14368090>, False)
(<Metabolite 23cump_p at 0x7f3b155c9b50>, False)
(<Metabolite udpLa4fn_c at 0x7f3b14368290>, True)
(<Metabolite uacgam_e at 0x7f3b14368190>, False)
(<Metabolite ocdcaACP_c at 0x7f3b155c9c50>, False)
(<Metabolite pg160_c at 0x7f3b155c9d50>, True)
(<Metabolite 12dgr120_c at 0x7f3b155b8b10>, True)
(<Metabolite pa160_p at 0x7f3b14368990>, True)
(<Metabolite 2odec11eg3p_c at 0x7f3b155c9f50>, True)
(<Metabolite 12ppd__R_p at 0x7f3b14368690>, True)
(<Metabolite f6p_p at 0x7f3b14368a90>, False)
(<Metabolite kdo2lipid4_e at 0x7f3b14368b90>, True)
(<Metabolite 5pg35pg_c at 0x7f3b14368890>, True)
(<Metabolite urate_p at 0x7f3b14368d90>, False)
(<Metabolite ala__D_c at 0x7f3b14368f90>, True)
(<Metabolite alac__S_c at 0x7f3b14368490>, True)
(<Metabolite dcdp_c at 0x7f3b1430a9d0>, True)
(<Metabolite db4p_c at 0x7f3b1416b0d0>, True)
(<Metabolite nmn_c at 0x7f3b14368c90>, True)
(<Metabolite h2o2_c at 0x7f3b155c9550>, True)
(<Metabolite malcoa_c at 0x7f3b14368590>, True)
(<Metabolite xyl__D_e at 0x7f3b14368e90>, False)
(<Metabolite galctn__D_e at 0x7f3b07f81410>, False)
(<Metabolite fmnh2_c at 0x7f3b1416b9d0>, True)
(<Metabolite alaala_c at 0x7f3b1430a4d0>, True)
(<Metabolite spmd_p at 0x7f3b155c9350>, True)
(<Metabolite ni2_p at 0x7f3b1416b3d0>, True)
(<Metabolite xmp_p at 0x7f3b1416b8d0>, False)
(<Metabolite pacald_e at 0x7f3b1416b6d0>, False)
(<Metabolite anhgm_c at 0x7f3b1416bcd0>, True)
(<Metabolite LalaDgluMdapDala_p at 0x7f3b07a94c10>, True)
(<Metabolite garagund_c at 0x7f3b1416bdd0>, False)
(<Metabolite o16a3und_p at 0x7f3b1416b1d0>, False)
(<Metabolite sulfac_p at 0x7f3b1416b5d0>, False)
(<Metabolite cu2_c at 0x7f3b14153110>, True)
(<Metabolite tcynt_e at 0x7f3b1416bad0>, False)
(<Metabolite 14glucan_c at 0x7f3b1416bbd0>, False)
(<Metabolite cdpdodec11eg_c at 0x7f3b14153410>, True)
(<Metabolite pgp120_p at 0x7f3b1430a5d0>, True)
(<Metabolite 1agpg180_p at 0x7f3b07f81290>, True)
(<Metabolite psclys_c at 0x7f3b14153510>, False)
(<Metabolite colipap_e at 0x7f3b14153910>, True)
(<Metabolite dhgly_c at 0x7f3b1430a8d0>, True)
(<Metabolite lipopb_c at 0x7f3b14153210>, False)
(<Metabolite 2ippm_c at 0x7f3b14153e10>, True)
(<Metabolite 3psme_c at 0x7f3b1416bed0>, True)
(<Metabolite imacp_c at 0x7f3b07f814d0>, True)
(<Metabolite xan_e at 0x7f3b14153f10>, True)
(<Metabolite ttdcea_e at 0x7f3b1416b4d0>, False)
(<Metabolite tma_c at 0x7f3b14153b10>, False)
(<Metabolite uama_c at 0x7f3b14153d10>, True)
(<Metabolite trp__L_p at 0x7f3b1419f550>, True)
(<Metabolite lcts_p at 0x7f3b07f81590>, False)
(<Metabolite fruur_e at 0x7f3b1419f350>, False)
(<Metabolite frulys_p at 0x7f3b07f81450>, False)
(<Metabolite pmtcoa_c at 0x7f3b1419f150>, True)
(<Metabolite dump_e at 0x7f3b14368390>, False)
(<Metabolite 3amp_p at 0x7f3b1419f750>, False)
(<Metabolite kphphhlipa_c at 0x7f3b1430acd0>, True)
(<Metabolite gagicolipa_c at 0x7f3b07f81610>, True)
(<Metabolite hg2_p at 0x7f3b1419fb50>, False)
(<Metabolite 2amsa_c at 0x7f3b1419fa50>, True)
(<Metabolite dsbaox_p at 0x7f3b1419f850>, False)
(<Metabolite pa161_p at 0x7f3b1419fe50>, True)
(<Metabolite ca2_c at 0x7f3b14153610>, True)
(<Metabolite galctn__L_p at 0x7f3b1419fd50>, False)
(<Metabolite 2fe1s_c at 0x7f3b14153310>, False)
(<Metabolite flxso_c at 0x7f3b141a3590>, False)
(<Metabolite gal_c at 0x7f3b141a3190>, True)
(<Metabolite phom_c at 0x7f3b07f810d0>, True)
(<Metabolite glc__D_e at 0x7f3b141a3390>, True)
(<Metabolite 3odcoa_c at 0x7f3b07f81510>, True)
(<Metabolite ugmda_c at 0x7f3b141a3290>, True)
(<Metabolite mobd_e at 0x7f3b1419f250>, True)
(<Metabolite nh4_e at 0x7f3b141a3a90>, True)
(<Metabolite idp_c at 0x7f3b1419ff50>, True)
(<Metabolite ahdt_c at 0x7f3b141a3490>, True)
(<Metabolite hdca_e at 0x7f3b14153710>, False)
(<Metabolite cenchddd_c at 0x7f3b141a3c90>, False)
(<Metabolite uacmamu_c at 0x7f3b141a3b90>, True)
(<Metabolite hxcoa_c at 0x7f3b07eff1d0>, True)
(<Metabolite cynt_p at 0x7f3b1419fc50>, False)
(<Metabolite 3hcinnm_p at 0x7f3b141a3890>, False)
(<Metabolite ura_p at 0x7f3b07eff6d0>, True)
(<Metabolite fald_e at 0x7f3b141a3990>, False)
(<Metabolite uacgam_p at 0x7f3b07eff3d0>, False)
(<Metabolite murein5p5p5p_p at 0x7f3b141a3e90>, True)
(<Metabolite murein4px4p_p at 0x7f3b07eff2d0>, True)
(<Metabolite tmrs2eACP_c at 0x7f3b07eff4d0>, False)
(<Metabolite pe180_c at 0x7f3b07eff8d0>, True)
(<Metabolite cpg180_c at 0x7f3b1419f450>, True)
(<Metabolite pg120_p at 0x7f3b07effcd0>, True)
(<Metabolite 2hdec9eg3p_c at 0x7f3b07effad0>, True)
(<Metabolite cl_c at 0x7f3b07eff9d0>, True)
(<Metabolite 2oxpaccoa_c at 0x7f3b07f81750>, False)
(<Metabolite g6p_c at 0x7f3b07eff7d0>, True)
(<Metabolite trdrd_c at 0x7f3b07ed7310>, False)
(<Metabolite mnl1p_c at 0x7f3b07efffd0>, True)
(<Metabolite agm_c at 0x7f3b07effbd0>, True)
(<Metabolite prpp_c at 0x7f3b07ed7110>, True)
(<Metabolite histd_c at 0x7f3b155c9e50>, True)
(<Metabolite orot_c at 0x7f3b07f818d0>, True)
(<Metabolite damp_c at 0x7f3b07effed0>, True)
(<Metabolite fmn_c at 0x7f3b07ed7710>, True)
(<Metabolite 3oddcoa_c at 0x7f3b07ed7510>, True)
(<Metabolite trnaglu_c at 0x7f3b07ed7d10>, False)
(<Metabolite ins_e at 0x7f3b141a3690>, True)
(<Metabolite q8_c at 0x7f3b07ed7810>, True)
(<Metabolite orn_c at 0x7f3b141a3790>, True)
(<Metabolite 2ombzl_c at 0x7f3b07ed7e10>, True)
(<Metabolite gthox_e at 0x7f3b07f17050>, False)
(<Metabolite etha_c at 0x7f3b07ed7910>, True)
(<Metabolite betald_c at 0x7f3b07effdd0>, False)
(<Metabolite hdca_c at 0x7f3b141a3090>, True)
(<Metabolite fgam_c at 0x7f3b07f17250>, True)
(<Metabolite dd2coa_c at 0x7f3b07eff0d0>, True)
(<Metabolite iasp_c at 0x7f3b07f817d0>, True)
(<Metabolite fru_p at 0x7f3b07f17450>, False)
(<Metabolite indole_p at 0x7f3b07f17550>, True)
(<Metabolite ppal_c at 0x7f3b14368790>, False)
(<Metabolite 12dgr161_c at 0x7f3b07f17350>, True)
(<Metabolite tartr__D_c at 0x7f3b07f17850>, False)
(<Metabolite 3oxdhscoa_c at 0x7f3b07ed7f10>, False)
(<Metabolite gslnt_c at 0x7f3b07f17950>, True)
(<Metabolite ampnt_c at 0x7f3b07ed7610>, False)
(<Metabolite f6p_c at 0x7f3b07f17b50>, True)
(<Metabolite ametam_c at 0x7f3b07f06290>, True)
(<Metabolite pphn_c at 0x7f3b07f81210>, True)
(<Metabolite prlp_c at 0x7f3b07f17f50>, True)
(<Metabolite 2mahmp_c at 0x7f3b07f17e50>, True)
(<Metabolite nicrnt_c at 0x7f3b07f17d50>, True)
(<Metabolite o2_e at 0x7f3b07f17650>, True)
(<Metabolite succ_e at 0x7f3b07f06490>, True)
(<Metabolite mql8_c at 0x7f3b07f06090>, True)
(<Metabolite xtsn_e at 0x7f3b07f81910>, True)
(<Metabolite 5dglcn_c at 0x7f3b07f17c50>, True)
(<Metabolite mmet_e at 0x7f3b07f06a90>, False)
(<Metabolite N1aspmd_c at 0x7f3b14153810>, True)
(<Metabolite methf_c at 0x7f3b07f17750>, True)
(<Metabolite ala__L_p at 0x7f3b07eff5d0>, True)
(<Metabolite galur_p at 0x7f3b07f06590>, False)
(<Metabolite for_p at 0x7f3b07f06f90>, True)
(<Metabolite fecrm_e at 0x7f3b07f06390>, False)
(<Metabolite mal__D_e at 0x7f3b07f352d0>, False)
(<Metabolite g3pg_p at 0x7f3b07f06690>, True)
(<Metabolite ppgpp_c at 0x7f3b07f06e90>, True)
(<Metabolite ethso3_c at 0x7f3b07f06890>, False)
(<Metabolite acgam1p_p at 0x7f3b07ed7410>, False)
(<Metabolite murein5px4p_p at 0x7f3b07f351d0>, True)
(<Metabolite dcaACP_c at 0x7f3b07f81850>, False)
(<Metabolite 3hcddec5eACP_c at 0x7f3b07f357d0>, False)
(<Metabolite 2agpg140_p at 0x7f3b07f81a50>, True)
(<Metabolite 1agpe180_p at 0x7f3b07f06c90>, True)
(<Metabolite 1agpg141_p at 0x7f3b07f355d0>, True)
(<Metabolite sufbcd_c at 0x7f3b07f35cd0>, False)
(<Metabolite nadphx__R_c at 0x7f3b07ed7210>, True)
(<Metabolite oaa_c at 0x7f3b07f35ed0>, True)
(<Metabolite tre6p_c at 0x7f3b07f350d0>, True)
(<Metabolite man6p_c at 0x7f3b07f06990>, True)
(<Metabolite fprica_c at 0x7f3b07f35fd0>, True)
(<Metabolite mana_c at 0x7f3b07f35bd0>, False)
(<Metabolite glcn_e at 0x7f3b07f353d0>, True)
(<Metabolite lipidA_c at 0x7f3b07f35dd0>, True)
(<Metabolite sbt6p_c at 0x7f3b142e9610>, True)
(<Metabolite csn_c at 0x7f3b142e9810>, True)
(<Metabolite ap5a_c at 0x7f3b07f354d0>, False)
(<Metabolite seln_c at 0x7f3b07f81ad0>, True)
(<Metabolite apoACP_c at 0x7f3b07f358d0>, False)
(<Metabolite ump_e at 0x7f3b142e9110>, False)
(<Metabolite enter_p at 0x7f3b142e9510>, True)
(<Metabolite o2s_e at 0x7f3b142e9910>, False)
(<Metabolite 3cmp_p at 0x7f3b07f359d0>, False)
(<Metabolite crn__D_c at 0x7f3b142e9710>, False)
(<Metabolite udpgal_e at 0x7f3b142e9e10>, False)
(<Metabolite udpacgal_p at 0x7f3b142e9b10>, False)
(<Metabolite glyc2p_e at 0x7f3b142ba150>, False)
(<Metabolite murein5p3p_p at 0x7f3b142e9c10>, True)
(<Metabolite pa180_c at 0x7f3b07f06190>, True)
(<Metabolite didp_c at 0x7f3b142e9f10>, True)
(<Metabolite 2agpg141_p at 0x7f3b142ba250>, True)
(<Metabolite 1hdec9eg3p_p at 0x7f3b142ba050>, True)
(<Metabolite iscu_4fe4s_c at 0x7f3b142ba650>, False)
(<Metabolite cm_p at 0x7f3b142e9d10>, False)
(<Metabolite cur_c at 0x7f3b142baa50>, False)
(<Metabolite prcp_c at 0x7f3b142e9310>, False)
(<Metabolite succ_c at 0x7f3b142ba350>, True)
(<Metabolite gam6p_c at 0x7f3b142bae50>, True)
(<Metabolite aps_c at 0x7f3b142e9a10>, True)
(<Metabolite thdp_c at 0x7f3b142bab50>, True)
(<Metabolite cdp_c at 0x7f3b155a0090>, True)
(<Metabolite ipdp_c at 0x7f3b142bad50>, True)
(<Metabolite ppbng_c at 0x7f3b142bac50>, True)
(<Metabolite pheme_c at 0x7f3b142ba450>, True)
(<Metabolite gua_e at 0x7f3b155a0390>, True)
(<Metabolite 12ppd__S_c at 0x7f3b142e9210>, True)
(<Metabolite 2ohph_c at 0x7f3b142baf50>, True)
(<Metabolite sucglu_c at 0x7f3b07f81810>, True)
(<Metabolite op4en_c at 0x7f3b155a0690>, False)
(<Metabolite dmso_c at 0x7f3b155a0490>, False)
(<Metabolite dtdp4d6dm_c at 0x7f3b07f819d0>, True)
(<Metabolite malttr_c at 0x7f3b155a0990>, False)
(<Metabolite sucarg_c at 0x7f3b142ba550>, True)
(<Metabolite arab__L_p at 0x7f3b155a0e90>, False)
(<Metabolite gsn_p at 0x7f3b142ba850>, True)
(<Metabolite no3_p at 0x7f3b155a0d90>, False)
(<Metabolite ddca_p at 0x7f3b155a0c90>, True)
(<Metabolite mobd_c at 0x7f3b155a0290>, True)
(<Metabolite fecrm_un_e at 0x7f3b155a0b90>, False)
(<Metabolite g3pi_e at 0x7f3b1559c1d0>, False)
(<Metabolite g3pc_e at 0x7f3b155a0590>, False)
(<Metabolite 23camp_p at 0x7f3b1559c0d0>, False)
(<Metabolite uLa4n_c at 0x7f3b1559c6d0>, True)
(<Metabolite tyrp_p at 0x7f3b1559c8d0>, False)
(<Metabolite ps181_c at 0x7f3b1559c5d0>, True)
(<Metabolite pgp140_p at 0x7f3b15978310>, True)
(<Metabolite 2agpg141_c at 0x7f3b155a0f90>, True)
(<Metabolite 2agpg161_c at 0x7f3b155a0890>, True)
(<Metabolite cysi__L_p at 0x7f3b1559c3d0>, False)
(<Metabolite 2ddara_c at 0x7f3b155a0190>, False)
(<Metabolite s7p_c at 0x7f3b1559ced0>, True)
(<Metabolite prfp_c at 0x7f3b1559c4d0>, True)
(<Metabolite csn_e at 0x7f3b1559ccd0>, False)
(<Metabolite kdo8p_c at 0x7f3b142ba750>, True)
(<Metabolite ser__L_e at 0x7f3b1559cdd0>, True)
(<Metabolite amob_c at 0x7f3b1559cbd0>, False)
(<Metabolite ttdca_e at 0x7f3b1559cfd0>, False)
(<Metabolite mmcoa__S_c at 0x7f3b1556b610>, True)
(<Metabolite glyc__R_c at 0x7f3b1559cad0>, True)
(<Metabolite dms_c at 0x7f3b1559c2d0>, False)
(<Metabolite 2dh3dgal_c at 0x7f3b1556b710>, False)
(<Metabolite ddcaACP_c at 0x7f3b1556b210>, False)
(<Metabolite hkndd_c at 0x7f3b1556ba10>, False)
(<Metabolite all6p_c at 0x7f3b1556bd10>, True)
(<Metabolite allul6p_c at 0x7f3b1556bc10>, True)
(<Metabolite galt_p at 0x7f3b1559c7d0>, False)
(<Metabolite glc__D_p at 0x7f3b1556b410>, True)
(<Metabolite phe__L_p at 0x7f3b1556bf10>, True)
(<Metabolite tsul_p at 0x7f3b1556be10>, False)
(<Metabolite thm_p at 0x7f3b15571250>, False)
(<Metabolite arbtn_fe3_e at 0x7f3b155a0790>, False)
(<Metabolite cl_e at 0x7f3b15571050>, True)
(<Metabolite stcoa_c at 0x7f3b07f06d90>, True)
(<Metabolite damp_p at 0x7f3b15571550>, False)
(<Metabolite 3gmp_e at 0x7f3b15571650>, False)
(<Metabolite udpglcur_p at 0x7f3b07f81a10>, False)
(<Metabolite tddec2eACP_c at 0x7f3b1556b910>, False)
(<Metabolite pe180_p at 0x7f3b1556b110>, True)
(<Metabolite 2agpe181_c at 0x7f3b15571350>, True)
(<Metabolite 3hpp_e at 0x7f3b15571150>, True)
(<Metabolite opmeACP_c at 0x7f3b15571b50>, False)
(<Metabolite meoh_p at 0x7f3b15571f50>, False)
(<Metabolite bwco1gdp_c at 0x7f3b07f81c10>, True)
(<Metabolite acmet_c at 0x7f3b1556b510>, True)
(<Metabolite nadhx__S_c at 0x7f3b15571e50>, True)
(<Metabolite 23dhmp_c at 0x7f3b15551390>, True)
(<Metabolite hmbil_c at 0x7f3b1559c9d0>, True)
(<Metabolite no3_e at 0x7f3b15571850>, False)
(<Metabolite ara5p_c at 0x7f3b15571d50>, True)
(<Metabolite kdo_c at 0x7f3b15551690>, True)
(<Metabolite duri_e at 0x7f3b15551290>, False)
(<Metabolite 2omph_c at 0x7f3b15551090>, True)
(<Metabolite scl_c at 0x7f3b15551790>, True)
(<Metabolite pppg9_c at 0x7f3b07f81b10>, True)
(<Metabolite acnam_e at 0x7f3b15551590>, False)
(<Metabolite inost_c at 0x7f3b15571a50>, False)
(<Metabolite gmhep1p_c at 0x7f3b15571950>, True)
(<Metabolite ttdcea_c at 0x7f3b15551b90>, True)
(<Metabolite ni2_e at 0x7f3b1556bb10>, True)
(<Metabolite ch4_e at 0x7f3b15551c90>, False)
(<Metabolite murein5px4px4p_p at 0x7f3b15571450>, True)
(<Metabolite pg141_c at 0x7f3b142533d0>, True)
(<Metabolite pa120_c at 0x7f3b07ed7b10>, True)
(<Metabolite gthox_p at 0x7f3b15551e90>, False)
(<Metabolite 2agpe161_c at 0x7f3b15551190>, True)
(<Metabolite forcoa_c at 0x7f3b142535d0>, True)
(<Metabolite moadcosh_c at 0x7f3b142538d0>, False)
(<Metabolite ttrcyc_e at 0x7f3b142534d0>, False)
(<Metabolite ribflv_c at 0x7f3b07f81b90>, True)
(<Metabolite lac__L_e at 0x7f3b142531d0>, True)
(<Metabolite so4_c at 0x7f3b07f81d50>, True)
(<Metabolite itp_c at 0x7f3b142536d0>, True)
(<Metabolite 2mcit_c at 0x7f3b1556b810>, True)
(<Metabolite dtdpglu_c at 0x7f3b15551890>, True)
(<Metabolite g3pi_c at 0x7f3b14253cd0>, False)
(<Metabolite h2mb4p_c at 0x7f3b142530d0>, True)
(<Metabolite galct__D_p at 0x7f3b1423c210>, False)
(<Metabolite glcur_p at 0x7f3b14253ed0>, False)
(<Metabolite maltpt_p at 0x7f3b1423c310>, False)
(<Metabolite so4_p at 0x7f3b15551d90>, True)
(<Metabolite feoxam_un_c at 0x7f3b14253fd0>, False)
(<Metabolite mso3_c at 0x7f3b15571c50>, False)
(<Metabolite Sfglutth_c at 0x7f3b15551990>, False)
(<Metabolite pe140_c at 0x7f3b1423c610>, True)
(<Metabolite pgp120_c at 0x7f3b1423cb10>, True)
(<Metabolite clpn180_p at 0x7f3b07f81b50>, True)
(<Metabolite 2agpe180_p at 0x7f3b1423c910>, True)
(<Metabolite gam6p_p at 0x7f3b1423c410>, False)
(<Metabolite meoh_c at 0x7f3b1423c710>, False)
(<Metabolite fe3dcit_c at 0x7f3b1423c510>, False)
(<Metabolite 4hthr_c at 0x7f3b14253bd0>, False)
(<Metabolite cit_c at 0x7f3b1423ce10>, True)
(<Metabolite skm5p_c at 0x7f3b14253ad0>, True)
(<Metabolite td2coa_c at 0x7f3b14253dd0>, True)
(<Metabolite tagur_c at 0x7f3b07f8f450>, False)
(<Metabolite acgam_e at 0x7f3b1423cd10>, False)
(<Metabolite pnto__R_e at 0x7f3b07f8f150>, False)
(<Metabolite dtdprmn_c at 0x7f3b07f8f050>, True)
(<Metabolite 3dhguln_c at 0x7f3b07f81dd0>, False)
(<Metabolite hqn_c at 0x7f3b07f8f750>, False)
(<Metabolite glucys_c at 0x7f3b141a3d90>, True)
(<Metabolite minohp_e at 0x7f3b07f8f550>, False)
(<Metabolite ac_p at 0x7f3b07f81d90>, True)
(<Metabolite malthx_p at 0x7f3b07f8f350>, False)
(<Metabolite cgly_e at 0x7f3b07f8fb50>, True)
(<Metabolite fecrm_un_p at 0x7f3b07f8fd50>, False)
(<Metabolite o16a4colipa_p at 0x7f3b1423cc10>, False)
(<Metabolite aso3_p at 0x7f3b07f8ff50>, False)
(<Metabolite thrp_p at 0x7f3b07fa3090>, False)
(<Metabolite cys__D_p at 0x7f3b07fa3190>, False)
(<Metabolite ag_c at 0x7f3b07f8f650>, False)
(<Metabolite 1ddecg3p_c at 0x7f3b1423c110>, True)
(<Metabolite pg180_p at 0x7f3b07f8fc50>, True)
(<Metabolite 2odec11eg3p_p at 0x7f3b07fa3290>, True)
(<Metabolite 12ppd__R_e at 0x7f3b07fa3790>, True)
(<Metabolite 1agpe140_p at 0x7f3b07fa3890>, True)
(<Metabolite rephaccoa_c at 0x7f3b07fa3490>, False)
(<Metabolite 2fe2s_c at 0x7f3b07f81e50>, True)
(<Metabolite 23doguln_p at 0x7f3b07fa3590>, False)
(<Metabolite 6pgl_c at 0x7f3b07fa3390>, True)
(<Metabolite ptrc_c at 0x7f3b142539d0>, True)
(<Metabolite 2dda7p_c at 0x7f3b07f8f850>, True)
(<Metabolite sl2a6o_c at 0x7f3b07fa3e90>, True)
(<Metabolite cmp_c at 0x7f3b07fa3a90>, True)
(<Metabolite uacgam_c at 0x7f3b142537d0>, True)
(<Metabolite uaccg_c at 0x7f3b07f8d0d0>, True)
(<Metabolite lipidAds_c at 0x7f3b07fa3d90>, True)
(<Metabolite fc1p_c at 0x7f3b07f8fa50>, True)
(<Metabolite btn_c at 0x7f3b07f8d4d0>, True)
(<Metabolite cbl1_e at 0x7f3b07fa3f90>, False)
(<Metabolite xylu__L_c at 0x7f3b07f81e10>, False)
(<Metabolite xylu__L_e at 0x7f3b07f8d9d0>, False)
(<Metabolite arg__L_p at 0x7f3b07f81ed0>, True)
(<Metabolite gam_p at 0x7f3b15551a90>, False)
(<Metabolite glyb_p at 0x7f3b07f8d5d0>, False)
(<Metabolite lac__L_p at 0x7f3b07f8dfd0>, True)
(<Metabolite pydx_e at 0x7f3b07f8ded0>, False)
(<Metabolite metsox_R__L_c at 0x7f3b07f8dad0>, True)
(<Metabolite hmgth_c at 0x7f3b07f8dcd0>, False)
(<Metabolite sel_e at 0x7f3b1423ca10>, True)
(<Metabolite glyc__R_e at 0x7f3b07f8d8d0>, True)
(<Metabolite eca4colipa_e at 0x7f3b07f8d3d0>, True)
(<Metabolite no_c at 0x7f3b07fa3c90>, False)
(<Metabolite cyan_e at 0x7f3b141f0410>, False)
(<Metabolite hom__L_p at 0x7f3b141f0110>, True)
(<Metabolite 3hddecACP_c at 0x7f3b141f0710>, False)
(<Metabolite cddec5eACP_c at 0x7f3b141f0210>, False)
(<Metabolite gthrd_p at 0x7f3b07f8d7d0>, True)
(<Metabolite 1odec11eg3p_p at 0x7f3b141f0310>, True)
(<Metabolite iscu_c at 0x7f3b141f0b10>, False)
(<Metabolite cxsam_c at 0x7f3b141f0510>, True)
(<Metabolite mteo2_c at 0x7f3b141f0910>, False)
(<Metabolite glyc_c at 0x7f3b141f0810>, True)
(<Metabolite cbasp_c at 0x7f3b141df050>, True)
(<Metabolite mqn8_c at 0x7f3b141df150>, True)
(<Metabolite fuc__L_e at 0x7f3b141f0f10>, False)
(<Metabolite malthp_c at 0x7f3b141df350>, False)
(<Metabolite tsul_e at 0x7f3b07f8ddd0>, False)
(<Metabolite lipa_cold_c at 0x7f3b141df650>, True)
(<Metabolite hxa_e at 0x7f3b141df750>, True)
(<Metabolite fe3hox_c at 0x7f3b141f0c10>, False)
(<Metabolite leu__L_p at 0x7f3b141df250>, True)
(<Metabolite lyx__L_p at 0x7f3b07f81150>, False)
(<Metabolite taur_p at 0x7f3b141f0e10>, False)
(<Metabolite h2o2_p at 0x7f3b141dfa50>, False)
(<Metabolite dimp_e at 0x7f3b141df450>, False)
(<Metabolite 3ump_e at 0x7f3b07f8d1d0>, False)
(<Metabolite anhgm_p at 0x7f3b141df550>, True)
(<Metabolite ethso3_e at 0x7f3b141dfc50>, False)
(<Metabolite n2o_p at 0x7f3b141e7290>, False)
(<Metabolite udpgal_p at 0x7f3b141df850>, False)
(<Metabolite 3oddecACP_c at 0x7f3b141dfd50>, False)
(<Metabolite pg181_c at 0x7f3b141dff50>, True)
(<Metabolite 12dgr141_c at 0x7f3b141e7390>, True)
(<Metabolite 3ooctdACP_c at 0x7f3b141e7790>, False)
(<Metabolite pgp161_p at 0x7f3b07f81c90>, True)
(<Metabolite ddca_c at 0x7f3b07fa3690>, True)
(<Metabolite acon_C_c at 0x7f3b141e7590>, True)
(<Metabolite 23dhacoa_c at 0x7f3b141e7890>, False)
(<Metabolite 3hadpcoa_c at 0x7f3b141e7a90>, False)
(<Metabolite 2dglc_p at 0x7f3b07f81f50>, False)
(<Metabolite acglu_c at 0x7f3b155a0a90>, True)
(<Metabolite 2obut_c at 0x7f3b141e7d90>, True)
(<Metabolite dmpp_c at 0x7f3b07f8dbd0>, True)
(<Metabolite rbflvrd_c at 0x7f3b141e7090>, True)
(<Metabolite tagdp__D_c at 0x7f3b141e7f90>, True)
(<Metabolite crn_c at 0x7f3b141dfe50>, False)
(<Metabolite dnad_c at 0x7f3b141e7490>, True)
(<Metabolite ala_B_e at 0x7f3b07f81f90>, False)
(<Metabolite lac__D_p at 0x7f3b141e7990>, True)
(<Metabolite ala__D_p at 0x7f3b07f415d0>, True)
(<Metabolite 3cmp_e at 0x7f3b07f410d0>, False)
(<Metabolite sarcs_c at 0x7f3b141f0d10>, False)
(<Metabolite butso3_e at 0x7f3b07f413d0>, False)
(<Metabolite acgal1p_p at 0x7f3b07f417d0>, False)
(<Metabolite acgal1p_e at 0x7f3b1423c810>, False)
(<Metabolite 3sala_c at 0x7f3b07f418d0>, False)
(<Metabolite 3hdecACP_c at 0x7f3b07fc3110>, False)
(<Metabolite cdec3eACP_c at 0x7f3b07ed7c10>, False)
(<Metabolite 3hcmrs7eACP_c at 0x7f3b07f412d0>, False)
(<Metabolite pe161_c at 0x7f3b141e7c90>, True)
(<Metabolite 2odecg3p_p at 0x7f3b07f41dd0>, True)
(<Metabolite 1tdecg3p_p at 0x7f3b07f57110>, True)
(<Metabolite psclys_e at 0x7f3b141e7e90>, False)
(<Metabolite tartr__D_p at 0x7f3b07f57610>, False)
(<Metabolite na15dap_c at 0x7f3b07f41fd0>, True)
(<Metabolite quin_e at 0x7f3b07f57210>, False)
(<Metabolite 3amac_c at 0x7f3b07f411d0>, True)
(<Metabolite fe3dhbzs3_c at 0x7f3b07f57310>, True)
(<Metabolite psuri_e at 0x7f3b07f41ed0>, False)
(<Metabolite dump_c at 0x7f3b07f57510>, True)
(<Metabolite 4mpetz_c at 0x7f3b07f416d0>, True)
(<Metabolite ru5p__L_c at 0x7f3b07f57e10>, True)
(<Metabolite sucr_e at 0x7f3b07f81d10>, False)
(<Metabolite lac__L_c at 0x7f3b07f81bd0>, True)
(<Metabolite urea_e at 0x7f3b07f41bd0>, True)
(<Metabolite gcald_c at 0x7f3b07f50150>, False)
(<Metabolite hdcea_e at 0x7f3b07f81390>, False)
(<Metabolite gdpddman_c at 0x7f3b07f57a10>, True)
(<Metabolite galct__D_c at 0x7f3b141df950>, False)
(<Metabolite dha_c at 0x7f3b07f50450>, True)
(<Metabolite gthrd_e at 0x7f3b07f57f10>, True)
(<Metabolite urdglyc_c at 0x7f3b07f50250>, True)
(<Metabolite dcacoa_c at 0x7f3b07f57410>, True)
(<Metabolite so3_e at 0x7f3b07f50550>, False)
(<Metabolite acgam_p at 0x7f3b141e7b90>, False)
(<Metabolite melib_p at 0x7f3b07f41cd0>, False)
(<Metabolite rmn_p at 0x7f3b07f81fd0>, False)
(<Metabolite galctn__D_p at 0x7f3b07f81890>, False)
(<Metabolite frulys_e at 0x7f3b07f81cd0>, False)
(<Metabolite cmp_e at 0x7f3b07f57810>, False)
(<Metabolite pydam_e at 0x7f3b141dfb50>, False)
(<Metabolite gmp_p at 0x7f3b07f57d10>, False)
(<Metabolite 4hoxpacd_p at 0x7f3b141f0610>, False)
(<Metabolite 3amp_e at 0x7f3b07f50650>, False)
(<Metabolite 14glucan_e at 0x7f3b07f50950>, False)
(<Metabolite athr__L_c at 0x7f3b07f57c10>, True)
(<Metabolite 3opalmACP_c at 0x7f3b07f50050>, False)
(<Metabolite 3hcvac11eACP_c at 0x7f3b07f50a50>, False)
(<Metabolite sq_p at 0x7f3b14281590>, False)
(<Metabolite acampnt_c at 0x7f3b079f4150>, False)
(<Metabolite udp_c at 0x7f3b07f50750>, True)
(<Metabolite hxan_c at 0x7f3b14281990>, True)
(<Metabolite 25aics_c at 0x7f3b14281390>, True)
(<Metabolite melib_e at 0x7f3b07f81e90>, False)
(<Metabolite gdpfuc_c at 0x7f3b14281e90>, True)
(<Metabolite unaga_c at 0x7f3b14281f90>, True)
(<Metabolite maltttr_e at 0x7f3b07f419d0>, False)
(<Metabolite glcur_e at 0x7f3b07f50e50>, False)
(<Metabolite crncoa_c at 0x7f3b14281a90>, False)
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(<Metabolite 2hdec9eg3p_p at 0x7f3b14129990>, True)
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/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars
/usr/local/lib/python2.7/dist-packages/sklearn/metrics/classification.py:516 RuntimeWarning: invalid value encountered in double_scalars

[u'athtp_c', u'uaagmda_c', u'uagmda_c', u'thmpp_c', u'btn_c', u'dann_c', u'thmmp_c', u'dtbt_c', u'kdo2lipid4_e', u'cxsam_c', u'malcoame_c', u'um4p_c', u'malcoa_c', u'5mta_c', u'enlipa_e', u'murein5px4p_p', u'murein4px4p_p', u'murein4px4px4p_p', u'murein4px4p4p_p', u'murein5px4px4p_p', u'murein3px4p_p', u'lipa_cold_e', u'lipa_e', u'amet_c', u'sbzcoa_c', u'ugmda_c', u'murein5p5p_p', u'murein5p4p_p', u'murein5p5p5p_p', u'anhgm4p_p', u'murein3px3p_p', u'murein4p4p_p', u'murein3p3p_p', u'murein5p3p_p', u'murein4p3p_p', u'anhgm3p_p', u'murein5px3p_p', u'ametam_c', u'5fthf_c', u'14dhncoa_c', u'ugmd_c', u'4mpetz_c', u'anhgm4p_c', u'ahcys_c', u'anhgm3p_c', u'methf_c', u'5mthf_c', u'hx2coa_c', u'3hhdcoa_c', u'btcoa_c', u'tdcoa_c', u'td2coa_c', u'ppcoa_c', u'3hodcoa_c', u'3hhcoa_c', u'hdcoa_c', u'3ohcoa_c', u'aacoa_c', u'tdecoa_c', u'succoa_c', u'od2coa_c', u'stcoa_c', u'b2coa_c', u'3otdcoa_c', u'3htdcoa_c', u'ddcacoa_c', u'odecoa_c', u'hdd2coa_c', u'3hbcoa_c', u'pmtcoa_c', u'3ohdcoa_c', u'3ohodcoa_c', u'LalaDgluMdap_e', u'LalaDgluMdapDala_e', u'LalaDgluMdapDala_c', u'LalaDgluMdap_c', u'LalaDgluMdap_p', u'LalaDgluMdapDala_p', u'dhf_c', u'10fthf_c', u'mlthf_c', u'thf_c', u'dpcoa_c', u'mmcoa__S_c', u'hxcoa_c', u'dcacoa_c', u'3oddcoa_c', u'occoa_c', u'3oocoa_c', u'prpncoa_c', u'dd2coa_c', u'dc2coa_c', u'3hocoa_c', u'3odcoa_c', u'oc2coa_c', u'3hddcoa_c', u'3hdcoa_c', u'kdo2lipid4_p', u'forcoa_c', u'2tpr3dpcoa_c', u'fad_c', u'fadh2_c', u'kdo2lipid4_c', u'kdolipid4_c', u'enlipa_p', u'anhm3p_c', u'anhm4p_c', u'fmnh2_c', u'fmn_c', u'u23ga_c', u'mococdp_c', u'fad_p', u'2omph_c', u'fad_e', u'na15dap_c', u'dhpt_c', u'spmd_c', u'kdo2lipid4L_c', u'kdo2lipid4p_c', u'lipa_p', u'lipa_cold_p', u'nadphx__S_c', u'lipidA_c', u'u3hga_c', u'nadphx__R_c', u'ribflv_c', u'pap_c', u'rbflvrd_c', u'fmn_e', u'fmn_p', u'hemeO_c', u'2ombzl_c', u'N1aspmd_c', u'n8aspmd_c', u'lipa_c', u'lipa_cold_c', u'u3aga_c', u'nadhx__R_c', u'nadhx__S_c', u'lipidAds_c', u'dmlz_c', u'udcpdp_p', u'udcpp_p', u'ribflv_p', u'q8_c', u'2ommbl_c', u'2omhmbl_c', u'q8h2_c', u'5mtr_c', u'spmd_e', u'5mtr_p', u'spmd_p', u'5mtr_e', u'2ohph_c', u'dnad_c', u'lipidX_c', u'uamag_c', u'6hmhptpp_c', u'2oph_c', u'mptamp_c', u'mpt_c', u'gtspmd_c', u'6hmhpt_c', u'3ophb_c', u'dhmpt_c', u'5apru_c', u'4r5au_c', u'5aprbu_c', u'prlp_c', u'paps_c', u'moco_c', u'bmoco_c', u'LalaDglu_c', u'bmoco1gdp_c', u'mocogdp_c', u'bmocogdp_c', u'25drapp_c', u'prfp_c', u'dhpmp_c', u'ahdt_c', u'prbamp_c', u'dhnpt_c', u'aps_c', u'thmnp_c', u'colipa_e', u'LalaLglu_c']
Im in loop 1 and I have 0 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b14599b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d41248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d410e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b63f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b61b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b6c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b158a4e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b158a4d88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44584950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1565b050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b2f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b2b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b25f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146a3dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b2f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146a3e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146a3d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146a3cf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44584710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15673170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b156732d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f27e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b16d1c908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445953b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b16d1ca28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b16d1c9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15649128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b156496c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aef80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147010e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b38c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b159dddd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b159dd290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b159ddef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b159dde18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a5c638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445512d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ada70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445569e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1421f488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
Im in loop 2 and I have 38 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b07daca70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8cef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e8fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452da70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1473d3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07670fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cf38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1a06c680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b09e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0779ccb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3ccb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e80e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e8248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e83b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445622d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0782ccf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445626c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a91b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abcb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ecb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479eb90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445627a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a71b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dbd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e85f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474ed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b078f22d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475bb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ef38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e87e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e8950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f86c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8c4d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8c3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8cf38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8c5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8cd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8c0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a70e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8c7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e8cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076e8710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8ca70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b8cdd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b078077a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07807878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b078077e8>
Im in loop 3 and I have 72 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b070795f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403e050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403e170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ec20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403e440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14774dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403e638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b660e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b66248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14371bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b66b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403ecb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b504d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b5c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07adba70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1403e368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b507a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f36ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445274d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445273f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445270e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445275f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b50b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b154feb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147018c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0716d098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14774d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aa5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b072f3fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14755290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aadd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aae60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aa950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aa320>
                    biomass1_5  biomass1_6  biomass1_8  biomass1_12  \
2omhmbl_c                    0           0           0            0
murein3p3p_p                 0           0           0            0
hxcoa_c                      0           0           0            0
LalaDgluMdap_p               0           0           0            0
hdcoa_c                      0           0           0            0
3hhcoa_c                     0           0           0            0
odecoa_c                     1           0           1            0
u3aga_c                      1           0           0            0
LalaDgluMdap_e               0           0           0            0
5mtr_e                       1           0           0            0
5fthf_c                      0           1           0            0
3hbcoa_c                     0           0           0            0
fmn_p                        0           0           0            0
mpt_c                        0           0           0            0
lipidAds_c                   0           0           0            0
murein5p3p_p                 0           0           0            0
5mtr_c                       0           0           0            0
dpcoa_c                      0           0           0            0
dhpt_c                       0           1           1            0
um4p_c                       0           0           0            0
LalaDglu_c                   0           1           0            0
u23ga_c                      0           0           0            0
dnad_c                       1           0           0            1
mptamp_c                     0           0           0            0
methf_c                      0           0           0            0
ppcoa_c                      0           0           0            0
malcoa_c                     0           0           1            0
prpncoa_c                    0           1           0            0
6hmhptpp_c                   0           0           0            1
3hdcoa_c                     0           0           0            1
...                        ...         ...         ...          ...
dmlz_c                       0           0           0            0
anhgm4p_c                    0           0           0            0
lipa_cold_p                  1           0           0            0
lipidX_c                     0           0           0            0
murein5p5p5p_p               0           0           0            0
rbflvrd_c                    0           0           1            1
pmtcoa_c                     0           0           0            0
ametam_c                     0           0           0            0
LalaDgluMdapDala_p           0           0           0            0
nadphx__S_c                  1           0           1            0
thmmp_c                      1           0           0            0
3odcoa_c                     0           0           0            0
tdecoa_c                     0           0           0            0
3otdcoa_c                    0           0           1            0
udcpdp_p                     0           1           1            0
ddcacoa_c                    0           0           0            0
occoa_c                      0           0           1            1
lipa_c                       0           0           0            0
spmd_c                       0           1           0            0
prlp_c                       0           0           0            0
3oddcoa_c                    0           1           1            0
sbzcoa_c                     0           0           0            0
ribflv_c                     0           0           0            1
fmn_c                        0           0           0            0
udcpp_p                      0           0           0            0
btn_c                        1           0           0            0
kdo2lipid4_p                 0           1           0            0
murein5px3p_p                0           0           1            0
aps_c                        1           1           0            0
dhmpt_c                      0           0           0            0

                    biomass1_19  biomass1_20  biomass1_22  biomass1_23  \
2omhmbl_c                     0            0            0            0
murein3p3p_p                  0            1            0            0
hxcoa_c                       0            0            1            0
LalaDgluMdap_p                0            0            0            0
hdcoa_c                       0            0            0            0
3hhcoa_c                      0            0            0            0
odecoa_c                      0            1            0            0
u3aga_c                       0            0            1            0
LalaDgluMdap_e                0            0            0            0
5mtr_e                        0            0            0            0
5fthf_c                       0            0            1            1
3hbcoa_c                      1            0            0            0
fmn_p                         0            0            0            0
mpt_c                         0            0            0            0
lipidAds_c                    0            0            1            0
murein5p3p_p                  0            1            0            0
5mtr_c                        0            0            0            0
dpcoa_c                       0            0            0            0
dhpt_c                        0            1            0            0
um4p_c                        0            1            0            0
LalaDglu_c                    0            0            0            0
u23ga_c                       0            1            0            1
dnad_c                        1            0            0            1
mptamp_c                      0            0            0            0
methf_c                       0            0            0            1
ppcoa_c                       0            0            0            0
malcoa_c                      1            0            0            0
prpncoa_c                     1            0            0            0
6hmhptpp_c                    0            0            0            0
3hdcoa_c                      0            0            0            0
...                         ...          ...          ...          ...
dmlz_c                        0            0            0            0
anhgm4p_c                     0            0            0            0
lipa_cold_p                   0            0            0            0
lipidX_c                      0            0            0            0
murein5p5p5p_p                0            0            0            0
rbflvrd_c                     0            0            0            0
pmtcoa_c                      0            0            0            0
ametam_c                      0            0            0            0
LalaDgluMdapDala_p            0            0            0            0
nadphx__S_c                   0            0            1            0
thmmp_c                       0            0            0            0
3odcoa_c                      0            0            0            0
tdecoa_c                      0            0            0            0
3otdcoa_c                     0            0            0            0
udcpdp_p                      0            0            0            0
ddcacoa_c                     0            0            1            0
occoa_c                       0            0            1            0
lipa_c                        0            0            0            0
spmd_c                        1            0            0            0
prlp_c                        0            0            0            0
3oddcoa_c                     0            0            0            0
sbzcoa_c                      0            0            0            0
ribflv_c                      0            0            0            0
fmn_c                         0            0            1            0
udcpp_p                       0            0            0            0
btn_c                         0            0            0            0
kdo2lipid4_p                  1            0            0            0
murein5px3p_p                 0            0            0            0
aps_c                         0            0            0            0
dhmpt_c                       0            0            0            1

                    biomass1_27  biomass1_28     ...       biomass3_69  \
2omhmbl_c                     0            0     ...                 1
murein3p3p_p                  0            0     ...                 0
hxcoa_c                       0            1     ...                 0
LalaDgluMdap_p                0            0     ...                 0
hdcoa_c                       0            0     ...                 0
3hhcoa_c                      0            0     ...                 0
odecoa_c                      0            0     ...                 0
u3aga_c                       0            0     ...                 0
LalaDgluMdap_e                0            0     ...                 0
5mtr_e                        0            0     ...                 0
5fthf_c                       0            0     ...                 0
3hbcoa_c                      0            0     ...                 0
fmn_p                         0            0     ...                 0
mpt_c                         1            0     ...                 0
lipidAds_c                    0            0     ...                 0
murein5p3p_p                  0            0     ...                 0
5mtr_c                        0            0     ...                 0
dpcoa_c                       0            0     ...                 0
dhpt_c                        0            0     ...                 0
um4p_c                        0            0     ...                 0
LalaDglu_c                    0            0     ...                 0
u23ga_c                       0            0     ...                 0
dnad_c                        1            0     ...                 0
mptamp_c                      0            0     ...                 0
methf_c                       0            0     ...                 1
ppcoa_c                       0            0     ...                 1
malcoa_c                      1            0     ...                 0
prpncoa_c                     0            0     ...                 0
6hmhptpp_c                    0            0     ...                 0
3hdcoa_c                      0            0     ...                 1
...                         ...          ...     ...               ...
dmlz_c                        0            0     ...                 0
anhgm4p_c                     0            0     ...                 0
lipa_cold_p                   0            0     ...                 0
lipidX_c                      0            0     ...                 1
murein5p5p5p_p                0            0     ...                 0
rbflvrd_c                     0            0     ...                 0
pmtcoa_c                      0            0     ...                 0
ametam_c                      0            0     ...                 0
LalaDgluMdapDala_p            0            0     ...                 0
nadphx__S_c                   0            0     ...                 0
thmmp_c                       0            0     ...                 1
3odcoa_c                      0            0     ...                 0
tdecoa_c                      0            0     ...                 0
3otdcoa_c                     1            0     ...                 0
udcpdp_p                      0            0     ...                 0
ddcacoa_c                     0            0     ...                 0
occoa_c                       1            0     ...                 0
lipa_c                        0            1     ...                 0
spmd_c                        0            0     ...                 0
prlp_c                        0            0     ...                 0
3oddcoa_c                     0            0     ...                 0
sbzcoa_c                      0            0     ...                 0
ribflv_c                      0            0     ...                 0
fmn_c                         0            0     ...                 0
udcpp_p                       0            0     ...                 0
btn_c                         0            0     ...                 0
kdo2lipid4_p                  0            1     ...                 0
murein5px3p_p                 0            0     ...                 0
aps_c                         0            0     ...                 1
dhmpt_c                       0            0     ...                 0

                    biomass3_71  biomass3_72  biomass3_75  biomass3_82  \
2omhmbl_c                     0            0            0            0
murein3p3p_p                  0            0            0            0
hxcoa_c                       0            0            0            0
LalaDgluMdap_p                0            0            0            1
hdcoa_c                       0            0            0            0
3hhcoa_c                      0            0            0            1
odecoa_c                      0            0            1            0
u3aga_c                       0            0            0            1
LalaDgluMdap_e                0            0            0            0
5mtr_e                        0            0            0            0
5fthf_c                       0            0            0            1
3hbcoa_c                      0            0            0            0
fmn_p                         0            0            0            0
mpt_c                         0            0            0            0
lipidAds_c                    0            0            0            1
murein5p3p_p                  0            0            0            0
5mtr_c                        0            0            0            0
dpcoa_c                       1            1            0            0
dhpt_c                        0            0            0            0
um4p_c                        0            0            0            0
LalaDglu_c                    0            0            0            0
u23ga_c                       0            0            0            0
dnad_c                        0            1            0            0
mptamp_c                      0            0            0            0
methf_c                       0            1            0            0
ppcoa_c                       0            0            0            0
malcoa_c                      0            0            0            0
prpncoa_c                     0            0            0            0
6hmhptpp_c                    0            0            0            0
3hdcoa_c                      0            0            0            0
...                         ...          ...          ...          ...
dmlz_c                        0            1            0            0
anhgm4p_c                     0            0            0            0
lipa_cold_p                   0            0            0            0
lipidX_c                      0            0            0            0
murein5p5p5p_p                1            0            1            0
rbflvrd_c                     1            0            0            1
pmtcoa_c                      0            0            0            0
ametam_c                      0            0            0            0
LalaDgluMdapDala_p            1            0            0            1
nadphx__S_c                   1            0            1            0
thmmp_c                       0            0            0            0
3odcoa_c                      0            0            0            0
tdecoa_c                      0            0            0            1
3otdcoa_c                     0            0            1            0
udcpdp_p                      0            0            0            0
ddcacoa_c                     0            0            1            0
occoa_c                       0            0            0            0
lipa_c                        0            0            1            0
spmd_c                        0            0            0            0
prlp_c                        0            0            0            0
3oddcoa_c                     1            0            0            0
sbzcoa_c                      0            0            0            0
ribflv_c                      0            0            0            0
fmn_c                         0            0            0            0
udcpp_p                       0            0            0            0
btn_c                         0            0            0            0
kdo2lipid4_p                  0            1            0            0
murein5px3p_p                 0            0            0            0
aps_c                         0            0            0            0
dhmpt_c                       0            0            0            0

                    biomass3_83  biomass3_84  biomass3_85  biomass3_86  \
2omhmbl_c                     0            0            0            0
murein3p3p_p                  0            0            0            0
hxcoa_c                       0            0            0            0
LalaDgluMdap_p                0            0            0            0
hdcoa_c                       1            0            1            0
3hhcoa_c                      0            1            0            0
odecoa_c                      0            0            0            0
u3aga_c                       0            1            0            0
LalaDgluMdap_e                0            0            0            0
5mtr_e                        0            0            0            0
5fthf_c                       0            1            0            0
3hbcoa_c                      0            1            0            1
fmn_p                         0            0            0            0
mpt_c                         0            1            0            0
lipidAds_c                    0            0            0            0
murein5p3p_p                  0            0            0            0
5mtr_c                        0            0            0            0
dpcoa_c                       0            0            0            1
dhpt_c                        0            1            0            0
um4p_c                        0            0            0            0
LalaDglu_c                    0            0            0            0
u23ga_c                       0            0            0            0
dnad_c                        0            0            0            1
mptamp_c                      0            0            0            0
methf_c                       1            0            0            0
ppcoa_c                       0            0            0            0
malcoa_c                      0            0            0            0
prpncoa_c                     0            0            0            0
6hmhptpp_c                    0            1            0            0
3hdcoa_c                      0            0            0            0
...                         ...          ...          ...          ...
dmlz_c                        0            0            0            0
anhgm4p_c                     0            0            0            0
lipa_cold_p                   0            0            1            0
lipidX_c                      0            0            0            0
murein5p5p5p_p                0            0            0            0
rbflvrd_c                     0            0            0            0
pmtcoa_c                      0            0            0            0
ametam_c                      0            0            1            0
LalaDgluMdapDala_p            0            0            0            0
nadphx__S_c                   0            0            0            0
thmmp_c                       0            0            0            0
3odcoa_c                      0            0            0            0
tdecoa_c                      0            0            0            0
3otdcoa_c                     0            0            0            0
udcpdp_p                      0            0            0            0
ddcacoa_c                     0            0            0            1
occoa_c                       0            0            1            0
lipa_c                        0            0            0            0
spmd_c                        0            0            0            0
prlp_c                        0            1            0            1
3oddcoa_c                     0            0            1            0
sbzcoa_c                      0            0            0            0
ribflv_c                      0            0            1            0
fmn_c                         0            0            0            0
udcpp_p                       0            0            0            0
btn_c                         0            0            0            0
kdo2lipid4_p                  0            1            0            0
murein5px3p_p                 0            0            0            0
aps_c                         0            0            0            0
dhmpt_c                       0            0            1            0

                    biomass3_90
2omhmbl_c                     1
murein3p3p_p                  1
hxcoa_c                       0
LalaDgluMdap_p                0
hdcoa_c                       0
3hhcoa_c                      0
odecoa_c                      0
u3aga_c                       0
LalaDgluMdap_e                0
5mtr_e                        0
5fthf_c                       0
3hbcoa_c                      0
fmn_p                         0
mpt_c                         0
lipidAds_c                    0
murein5p3p_p                  0
5mtr_c                        0
dpcoa_c                       0
dhpt_c                        0
um4p_c                        0
LalaDglu_c                    0
u23ga_c                       0
dnad_c                        0
mptamp_c                      0
methf_c                       0
ppcoa_c                       0
malcoa_c                      0
prpncoa_c                     0
6hmhptpp_c                    0
3hdcoa_c                      0
...                         ...
dmlz_c                        0
anhgm4p_c                     0
lipa_cold_p                   0
lipidX_c                      0
murein5p5p5p_p                0
rbflvrd_c                     0
pmtcoa_c                      1
ametam_c                      1
LalaDgluMdapDala_p            0
nadphx__S_c                   0
thmmp_c                       0
3odcoa_c                      0
tdecoa_c                      1
3otdcoa_c                     0
udcpdp_p                      0
ddcacoa_c                     0
occoa_c                       1
lipa_c                        0
spmd_c                        0
prlp_c                        0
3oddcoa_c                     0
sbzcoa_c                      1
ribflv_c                      0
fmn_c                         0
udcpp_p                       0
btn_c                         0
kdo2lipid4_p                  0
murein5px3p_p                 0
aps_c                         1
dhmpt_c                       0

[186 rows x 117 columns]
Im in loop 1 and I have 0 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b1a06c680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4458a1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aef80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445909e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f27e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ada70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445512d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147424d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592c170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140e0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592c638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b39e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592c7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b38c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1590c128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1590c290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ade60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b158fc0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454aa70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b158fc950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1590cc68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446255a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b4d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446257e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1470ed88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1591b998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b158fcb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592ca70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147085f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592cbd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592c5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b41b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b40e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f86c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8830>
Im in loop 2 and I have 41 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ead050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07af8d88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14774830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14774050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ca5b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abdd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1476eb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8e2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8e200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1473d7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07dca0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8eb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07692950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8a128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8a290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8a1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aa3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454abd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8e878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445276c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ac68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445274d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454aab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8e7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0756a680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8acf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e6db00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a70e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b142b0098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b6e758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14701dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147498c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8e710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b076533b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06f142d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b157bc320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a71b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b070a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146874d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ea75a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ee60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e8ee18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1592c998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3ce18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cf38>
Im in loop 3 and I have 74 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b07fe05f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454aa70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f883b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f882d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b5cc60290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abbd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446245a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147aae60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15599170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445569e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07e347a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f88f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445624d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0746f5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146fc560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a00e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a0248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140b3878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a03b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f85a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a6290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edf098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edf290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edf638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155a0ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edf560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edfa70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b072c93f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15599638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ec20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a4c098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140bfc68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b070e2518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edf6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07edfd40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b642d4d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445513f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0dd0>
                    biomass1_0  biomass1_5  biomass1_8  biomass1_9  \
murein5px3p_p                0           0           0           1
ribflv_p                     0           0           0           0
rbflvrd_c                    0           0           0           0
5aprbu_c                     0           0           0           0
pap_c                        0           0           0           1
2ohph_c                      0           0           0           0
mocogdp_c                    0           1           0           0
forcoa_c                     0           0           0           0
4r5au_c                      0           1           0           0
u23ga_c                      0           0           0           0
hx2coa_c                     1           0           0           0
aps_c                        0           0           1           0
4mpetz_c                     0           1           0           0
spmd_e                       1           0           0           0
anhgm3p_p                    0           0           1           1
nadhx__R_c                   0           0           0           0
kdo2lipid4_c                 0           0           0           0
lipa_e                       0           0           0           0
LalaDgluMdapDala_e           0           0           0           0
kdo2lipid4p_c                0           0           0           0
oc2coa_c                     0           0           0           0
bmoco1gdp_c                  0           0           0           0
mococdp_c                    0           1           0           0
14dhncoa_c                   1           0           0           0
ddcacoa_c                    0           0           0           0
nadphx__S_c                  0           0           0           0
stcoa_c                      0           0           0           0
dpcoa_c                      0           0           0           0
dd2coa_c                     0           0           1           0
enlipa_e                     0           0           0           0
...                        ...         ...         ...         ...
q8h2_c                       1           1           1           0
nadphx__R_c                  0           0           0           0
pmtcoa_c                     0           1           0           0
3oocoa_c                     0           0           1           0
spmd_c                       0           0           0           0
uagmda_c                     0           0           0           1
dc2coa_c                     0           0           0           0
2oph_c                       0           0           0           0
3ophb_c                      0           0           0           0
fad_p                        0           0           0           0
anhm3p_c                     1           0           0           0
kdo2lipid4_p                 0           0           0           0
5mtr_e                       0           0           0           0
5apru_c                      0           0           0           0
paps_c                       0           0           0           0
ahdt_c                       0           1           0           0
lipidA_c                     0           0           0           0
ametam_c                     0           0           1           0
mpt_c                        0           0           0           0
thf_c                        0           0           0           0
nadhx__S_c                   1           1           1           1
colipa_e                     1           0           0           0
murein5p4p_p                 0           0           0           0
ugmda_c                      1           0           0           0
hdd2coa_c                    0           0           0           0
amet_c                       1           0           0           0
fad_e                        0           0           0           0
10fthf_c                     0           0           0           0
lipa_p                       0           0           0           0
3odcoa_c                     0           0           0           0

                    biomass1_11  biomass1_14  biomass1_18  biomass1_20  \
murein5px3p_p                 0            0            0            0
ribflv_p                      0            0            0            0
rbflvrd_c                     0            0            0            0
5aprbu_c                      0            0            0            0
pap_c                         0            0            1            0
2ohph_c                       0            0            0            0
mocogdp_c                     0            0            0            0
forcoa_c                      0            0            0            1
4r5au_c                       0            0            0            0
u23ga_c                       0            0            0            0
hx2coa_c                      1            0            0            0
aps_c                         0            0            0            0
4mpetz_c                      0            1            0            0
spmd_e                        0            0            0            0
anhgm3p_p                     0            0            0            0
nadhx__R_c                    0            1            1            0
kdo2lipid4_c                  0            0            0            0
lipa_e                        0            0            0            1
LalaDgluMdapDala_e            0            0            0            0
kdo2lipid4p_c                 0            0            0            0
oc2coa_c                      0            0            1            0
bmoco1gdp_c                   1            0            0            0
mococdp_c                     0            0            0            1
14dhncoa_c                    0            0            0            1
ddcacoa_c                     0            0            0            0
nadphx__S_c                   0            0            0            1
stcoa_c                       0            0            0            0
dpcoa_c                       0            0            0            0
dd2coa_c                      0            0            0            0
enlipa_e                      0            0            0            0
...                         ...          ...          ...          ...
q8h2_c                        0            0            0            0
nadphx__R_c                   0            0            0            1
pmtcoa_c                      0            1            0            0
3oocoa_c                      0            0            0            0
spmd_c                        1            0            0            0
uagmda_c                      1            1            0            0
dc2coa_c                      0            0            0            0
2oph_c                        0            0            1            0
3ophb_c                       0            0            0            0
fad_p                         0            0            0            0
anhm3p_c                      1            0            0            0
kdo2lipid4_p                  0            1            0            1
5mtr_e                        0            1            0            0
5apru_c                       0            0            0            1
paps_c                        0            0            0            0
ahdt_c                        0            0            0            1
lipidA_c                      0            0            0            0
ametam_c                      0            0            0            0
mpt_c                         0            0            0            0
thf_c                         0            0            0            0
nadhx__S_c                    1            0            0            0
colipa_e                      0            0            0            0
murein5p4p_p                  0            0            0            0
ugmda_c                       0            0            0            0
hdd2coa_c                     0            0            0            0
amet_c                        0            0            0            0
fad_e                         0            0            0            0
10fthf_c                      0            0            0            0
lipa_p                        0            0            0            0
3odcoa_c                      0            0            0            0

                    biomass1_22  biomass1_23     ...       biomass3_65  \
murein5px3p_p                 0            0     ...                 0
ribflv_p                      0            0     ...                 0
rbflvrd_c                     0            0     ...                 0
5aprbu_c                      0            0     ...                 0
pap_c                         0            0     ...                 0
2ohph_c                       0            0     ...                 0
mocogdp_c                     0            0     ...                 0
forcoa_c                      0            1     ...                 0
4r5au_c                       0            0     ...                 1
u23ga_c                       1            1     ...                 1
hx2coa_c                      0            0     ...                 0
aps_c                         0            0     ...                 0
4mpetz_c                      1            0     ...                 0
spmd_e                        0            0     ...                 0
anhgm3p_p                     0            0     ...                 0
nadhx__R_c                    0            0     ...                 0
kdo2lipid4_c                  0            0     ...                 0
lipa_e                        0            0     ...                 0
LalaDgluMdapDala_e            0            0     ...                 0
kdo2lipid4p_c                 1            0     ...                 0
oc2coa_c                      0            0     ...                 1
bmoco1gdp_c                   0            0     ...                 0
mococdp_c                     0            0     ...                 0
14dhncoa_c                    0            0     ...                 0
ddcacoa_c                     0            1     ...                 0
nadphx__S_c                   0            0     ...                 1
stcoa_c                       0            0     ...                 0
dpcoa_c                       0            1     ...                 0
dd2coa_c                      0            1     ...                 0
enlipa_e                      0            0     ...                 0
...                         ...          ...     ...               ...
q8h2_c                        0            0     ...                 0
nadphx__R_c                   0            0     ...                 1
pmtcoa_c                      0            0     ...                 0
3oocoa_c                      0            1     ...                 0
spmd_c                        0            1     ...                 0
uagmda_c                      0            0     ...                 1
dc2coa_c                      1            1     ...                 0
2oph_c                        0            0     ...                 0
3ophb_c                       0            0     ...                 0
fad_p                         0            0     ...                 0
anhm3p_c                      0            0     ...                 0
kdo2lipid4_p                  0            1     ...                 0
5mtr_e                        0            0     ...                 0
5apru_c                       0            0     ...                 0
paps_c                        0            0     ...                 0
ahdt_c                        0            0     ...                 0
lipidA_c                      0            0     ...                 0
ametam_c                      0            0     ...                 0
mpt_c                         0            0     ...                 0
thf_c                         0            0     ...                 0
nadhx__S_c                    0            0     ...                 1
colipa_e                      1            0     ...                 0
murein5p4p_p                  0            0     ...                 0
ugmda_c                       0            0     ...                 1
hdd2coa_c                     0            0     ...                 1
amet_c                        0            0     ...                 0
fad_e                         0            0     ...                 0
10fthf_c                      0            0     ...                 1
lipa_p                        1            0     ...                 0
3odcoa_c                      0            0     ...                 0

                    biomass3_69  biomass3_71  biomass3_72  biomass3_74  \
murein5px3p_p                 0            0            0            0
ribflv_p                      0            0            0            0
rbflvrd_c                     0            0            0            0
5aprbu_c                      0            0            0            0
pap_c                         0            0            1            0
2ohph_c                       0            0            0            0
mocogdp_c                     0            0            0            0
forcoa_c                      0            0            0            0
4r5au_c                       0            1            0            0
u23ga_c                       0            0            1            0
hx2coa_c                      0            0            0            0
aps_c                         0            0            1            0
4mpetz_c                      0            0            0            0
spmd_e                        0            0            0            0
anhgm3p_p                     0            0            0            0
nadhx__R_c                    1            0            0            1
kdo2lipid4_c                  0            0            0            0
lipa_e                        1            1            0            0
LalaDgluMdapDala_e            1            0            0            0
kdo2lipid4p_c                 0            0            0            0
oc2coa_c                      0            0            0            0
bmoco1gdp_c                   0            0            0            0
mococdp_c                     0            0            1            0
14dhncoa_c                    0            0            0            0
ddcacoa_c                     0            0            0            0
nadphx__S_c                   1            1            1            0
stcoa_c                       0            0            0            0
dpcoa_c                       0            0            0            0
dd2coa_c                      0            0            0            0
enlipa_e                      0            0            0            0
...                         ...          ...          ...          ...
q8h2_c                        0            0            0            0
nadphx__R_c                   0            0            0            0
pmtcoa_c                      0            0            0            0
3oocoa_c                      0            0            0            0
spmd_c                        0            0            1            0
uagmda_c                      0            0            0            0
dc2coa_c                      0            0            0            0
2oph_c                        0            0            0            0
3ophb_c                       0            0            0            0
fad_p                         0            0            0            0
anhm3p_c                      1            1            0            0
kdo2lipid4_p                  0            0            0            1
5mtr_e                        0            0            0            0
5apru_c                       0            0            0            0
paps_c                        0            1            0            0
ahdt_c                        0            0            0            0
lipidA_c                      0            0            0            0
ametam_c                      0            1            0            0
mpt_c                         0            0            0            0
thf_c                         0            0            0            0
nadhx__S_c                    0            0            0            0
colipa_e                      0            0            0            0
murein5p4p_p                  0            0            0            0
ugmda_c                       0            0            1            1
hdd2coa_c                     0            0            0            0
amet_c                        0            0            0            0
fad_e                         0            0            0            0
10fthf_c                      0            0            0            1
lipa_p                        1            0            0            0
3odcoa_c                      0            0            0            0

                    biomass3_77  biomass3_81  biomass3_82  biomass3_84  \
murein5px3p_p                 0            0            0            0
ribflv_p                      0            0            0            0
rbflvrd_c                     0            0            0            0
5aprbu_c                      0            0            0            0
pap_c                         1            0            1            0
2ohph_c                       0            0            0            0
mocogdp_c                     0            0            0            0
forcoa_c                      0            0            0            0
4r5au_c                       0            1            0            1
u23ga_c                       0            1            0            0
hx2coa_c                      0            0            0            0
aps_c                         0            0            0            1
4mpetz_c                      0            0            0            0
spmd_e                        0            0            1            0
anhgm3p_p                     1            0            0            1
nadhx__R_c                    0            0            1            1
kdo2lipid4_c                  0            0            0            0
lipa_e                        0            0            0            0
LalaDgluMdapDala_e            0            0            0            0
kdo2lipid4p_c                 0            1            0            0
oc2coa_c                      1            1            0            0
bmoco1gdp_c                   0            0            0            0
mococdp_c                     0            1            0            0
14dhncoa_c                    0            0            0            0
ddcacoa_c                     0            0            1            0
nadphx__S_c                   1            0            0            0
stcoa_c                       0            0            0            0
dpcoa_c                       0            0            0            0
dd2coa_c                      0            0            0            0
enlipa_e                      0            0            0            0
...                         ...          ...          ...          ...
q8h2_c                        1            0            0            0
nadphx__R_c                   0            0            0            0
pmtcoa_c                      0            0            0            0
3oocoa_c                      0            1            0            1
spmd_c                        0            0            0            0
uagmda_c                      1            0            0            0
dc2coa_c                      1            0            0            0
2oph_c                        0            0            1            0
3ophb_c                       0            0            0            0
fad_p                         0            0            0            0
anhm3p_c                      0            0            1            0
kdo2lipid4_p                  0            0            0            1
5mtr_e                        0            0            0            0
5apru_c                       0            0            0            0
paps_c                        0            0            0            0
ahdt_c                        0            0            0            0
lipidA_c                      0            0            0            0
ametam_c                      0            0            0            1
mpt_c                         0            0            0            0
thf_c                         0            0            0            0
nadhx__S_c                    0            1            0            0
colipa_e                      0            1            0            0
murein5p4p_p                  0            0            0            1
ugmda_c                       0            0            0            0
hdd2coa_c                     0            0            0            0
amet_c                        0            0            1            0
fad_e                         0            0            0            0
10fthf_c                      0            0            0            0
lipa_p                        1            0            0            0
3odcoa_c                      0            0            1            0

                    biomass3_91
murein5px3p_p                 0
ribflv_p                      0
rbflvrd_c                     0
5aprbu_c                      0
pap_c                         0
2ohph_c                       0
mocogdp_c                     0
forcoa_c                      0
4r5au_c                       0
u23ga_c                       0
hx2coa_c                      0
aps_c                         0
4mpetz_c                      0
spmd_e                        0
anhgm3p_p                     0
nadhx__R_c                    0
kdo2lipid4_c                  0
lipa_e                        0
LalaDgluMdapDala_e            0
kdo2lipid4p_c                 0
oc2coa_c                      0
bmoco1gdp_c                   0
mococdp_c                     0
14dhncoa_c                    0
ddcacoa_c                     0
nadphx__S_c                   0
stcoa_c                       0
dpcoa_c                       0
dd2coa_c                      1
enlipa_e                      0
...                         ...
q8h2_c                        0
nadphx__R_c                   1
pmtcoa_c                      1
3oocoa_c                      0
spmd_c                        0
uagmda_c                      1
dc2coa_c                      0
2oph_c                        0
3ophb_c                       0
fad_p                         0
anhm3p_c                      0
kdo2lipid4_p                  0
5mtr_e                        1
5apru_c                       0
paps_c                        0
ahdt_c                        0
lipidA_c                      0
ametam_c                      0
mpt_c                         0
thf_c                         0
nadhx__S_c                    0
colipa_e                      1
murein5p4p_p                  1
ugmda_c                       0
hdd2coa_c                     1
amet_c                        0
fad_e                         0
10fthf_c                      1
lipa_p                        0
3odcoa_c                      0

[186 rows x 115 columns]
Im in loop 1 and I have 0 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445954d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445953b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140c31b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140c3560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140c36c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140c3320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140c3998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446245f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f42d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f45a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f49e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140f4e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b38c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3cf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b39e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f82d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147613b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7ea70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ade60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445275a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7e320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7ee18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a7edd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abd40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1476ed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ada70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abdd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749200>
Im in loop 2 and I have 42 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556d88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3ccb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147610e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b141070e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b5ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b57a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147619e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411dd40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147014d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147614d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445624d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411cea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ffcf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ffe60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411cdd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140fc170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140fc098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140fc5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ff7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147494d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411c830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140ffd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1411cbd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cc68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ab4a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446255a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a72d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a71b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abe18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b140fcd40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a70e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14701680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1410d560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0755e950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07adc0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478cb90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478c9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478c950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478c098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478cef0>
Im in loop 3 and I have 77 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b147495f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445510e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c04b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445273f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c041b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c04098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07d337a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146fcc20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b5dd83638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07d74ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f85a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c00290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f86c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c005f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c00320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0751da28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06c4a7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c00128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478c7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14797e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1470ef80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445adf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ada70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445514d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445512d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445513f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445511b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07603170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c00368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3ccf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147674d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14767200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07c00518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147673b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14749cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147083b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fadd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fab48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073fa200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073faf38>
                    biomass1_4  biomass1_5  biomass1_6  biomass1_8  \
dhmpt_c                      0           0           0           0
3ohodcoa_c                   0           0           0           0
LalaDgluMdapDala_p           0           0           0           1
prpncoa_c                    0           0           1           0
14dhncoa_c                   0           0           0           0
btcoa_c                      0           0           1           0
hdd2coa_c                    0           0           0           0
mococdp_c                    0           0           1           0
forcoa_c                     0           0           0           0
moco_c                       0           0           0           0
LalaDgluMdap_e               0           0           0           0
q8_c                         0           0           0           0
25drapp_c                    1           0           0           0
kdolipid4_c                  0           0           0           0
anhgm3p_c                    0           1           0           0
stcoa_c                      0           0           0           0
5mtr_p                       0           0           0           0
5mtr_e                       0           0           0           0
uamag_c                      1           0           1           0
dtbt_c                       0           0           0           0
murein5px4px4p_p             0           0           0           0
nadphx__S_c                  1           0           0           0
sbzcoa_c                     0           1           0           0
LalaDgluMdapDala_c           0           1           0           0
lipa_cold_c                  0           0           0           0
spmd_e                       0           0           1           1
fad_p                        0           0           0           0
ugmd_c                       0           0           0           1
murein4px4p4p_p              0           0           0           0
uaagmda_c                    0           0           0           0
...                        ...         ...         ...         ...
anhm4p_c                     1           0           0           0
dhpmp_c                      0           1           0           0
pap_c                        0           0           0           0
pmtcoa_c                     1           0           0           0
6hmhptpp_c                   0           0           1           0
nadphx__R_c                  0           1           0           0
3hhcoa_c                     0           0           0           0
5mtr_c                       0           0           0           0
2oph_c                       0           0           0           0
dann_c                       0           0           1           0
3hodcoa_c                    0           0           0           0
dhpt_c                       0           0           0           1
hxcoa_c                      0           0           0           0
thmmp_c                      0           1           0           0
murein4px4p_p                0           0           1           0
gtspmd_c                     0           0           0           0
q8h2_c                       1           0           0           0
2ohph_c                      1           0           0           0
2ombzl_c                     0           0           0           0
rbflvrd_c                    0           0           0           1
3oddcoa_c                    0           0           0           0
succoa_c                     0           0           0           0
fmnh2_c                      0           0           0           0
prbamp_c                     1           0           0           0
2omhmbl_c                    0           0           0           1
ribflv_c                     0           0           0           0
hemeO_c                      0           0           0           0
ahdt_c                       0           0           0           0
udcpdp_p                     0           1           0           0
fad_c                        0           0           0           1

                    biomass1_13  biomass1_15  biomass1_19  biomass1_23  \
dhmpt_c                       0            0            1            1
3ohodcoa_c                    0            1            1            0
LalaDgluMdapDala_p            0            0            0            0
prpncoa_c                     0            0            0            0
14dhncoa_c                    0            0            0            0
btcoa_c                       0            0            0            0
hdd2coa_c                     1            0            0            0
mococdp_c                     0            1            0            0
forcoa_c                      0            1            0            0
moco_c                        0            0            0            0
LalaDgluMdap_e                0            0            0            0
q8_c                          0            1            0            0
25drapp_c                     0            0            0            0
kdolipid4_c                   0            0            0            0
anhgm3p_c                     0            0            0            0
stcoa_c                       0            0            0            0
5mtr_p                        0            1            0            0
5mtr_e                        0            0            0            0
uamag_c                       0            0            0            0
dtbt_c                        0            0            1            0
murein5px4px4p_p              0            0            0            0
nadphx__S_c                   1            0            1            0
sbzcoa_c                      1            0            0            0
LalaDgluMdapDala_c            1            0            0            0
lipa_cold_c                   1            0            0            0
spmd_e                        0            0            0            0
fad_p                         0            0            0            1
ugmd_c                        1            0            1            0
murein4px4p4p_p               0            0            0            0
uaagmda_c                     0            0            0            0
...                         ...          ...          ...          ...
anhm4p_c                      0            1            0            0
dhpmp_c                       0            0            0            0
pap_c                         0            0            1            0
pmtcoa_c                      0            0            0            0
6hmhptpp_c                    0            0            0            0
nadphx__R_c                   0            0            0            1
3hhcoa_c                      0            0            0            1
5mtr_c                        0            0            0            0
2oph_c                        0            0            0            0
dann_c                        0            0            0            1
3hodcoa_c                     0            0            1            0
dhpt_c                        0            0            0            0
hxcoa_c                       0            0            0            1
thmmp_c                       0            0            0            0
murein4px4p_p                 0            0            0            0
gtspmd_c                      0            0            0            0
q8h2_c                        0            0            0            0
2ohph_c                       0            0            0            1
2ombzl_c                      0            0            0            0
rbflvrd_c                     0            0            0            0
3oddcoa_c                     0            0            0            1
succoa_c                      0            0            0            0
fmnh2_c                       0            0            0            1
prbamp_c                      0            0            0            0
2omhmbl_c                     0            0            0            0
ribflv_c                      0            1            0            0
hemeO_c                       0            1            1            0
ahdt_c                        0            0            0            0
udcpdp_p                      0            0            0            0
fad_c                         0            0            0            0

                    biomass1_25  biomass1_26     ...       biomass3_76  \
dhmpt_c                       0            0     ...                 0
3ohodcoa_c                    0            0     ...                 0
LalaDgluMdapDala_p            0            0     ...                 0
prpncoa_c                     1            0     ...                 0
14dhncoa_c                    0            0     ...                 0
btcoa_c                       0            0     ...                 0
hdd2coa_c                     0            0     ...                 0
mococdp_c                     0            0     ...                 1
forcoa_c                      1            0     ...                 0
moco_c                        0            0     ...                 1
LalaDgluMdap_e                0            0     ...                 0
q8_c                          0            0     ...                 0
25drapp_c                     0            0     ...                 0
kdolipid4_c                   0            0     ...                 0
anhgm3p_c                     0            0     ...                 0
stcoa_c                       1            0     ...                 0
5mtr_p                        0            0     ...                 0
5mtr_e                        0            1     ...                 1
uamag_c                       0            0     ...                 0
dtbt_c                        1            1     ...                 0
murein5px4px4p_p              0            0     ...                 0
nadphx__S_c                   0            0     ...                 0
sbzcoa_c                      0            0     ...                 0
LalaDgluMdapDala_c            0            0     ...                 1
lipa_cold_c                   0            0     ...                 0
spmd_e                        1            0     ...                 0
fad_p                         0            0     ...                 0
ugmd_c                        1            0     ...                 0
murein4px4p4p_p               0            1     ...                 0
uaagmda_c                     0            1     ...                 0
...                         ...          ...     ...               ...
anhm4p_c                      0            0     ...                 0
dhpmp_c                       0            1     ...                 0
pap_c                         0            0     ...                 0
pmtcoa_c                      0            0     ...                 0
6hmhptpp_c                    0            1     ...                 0
nadphx__R_c                   1            0     ...                 0
3hhcoa_c                      0            0     ...                 0
5mtr_c                        0            0     ...                 0
2oph_c                        0            0     ...                 0
dann_c                        0            0     ...                 0
3hodcoa_c                     0            0     ...                 0
dhpt_c                        0            0     ...                 0
hxcoa_c                       0            0     ...                 0
thmmp_c                       0            0     ...                 0
murein4px4p_p                 1            0     ...                 0
gtspmd_c                      0            0     ...                 0
q8h2_c                        0            0     ...                 0
2ohph_c                       0            0     ...                 0
2ombzl_c                      0            0     ...                 0
rbflvrd_c                     0            0     ...                 0
3oddcoa_c                     0            0     ...                 0
succoa_c                      0            0     ...                 0
fmnh2_c                       0            0     ...                 0
prbamp_c                      0            0     ...                 0
2omhmbl_c                     0            0     ...                 1
ribflv_c                      0            1     ...                 0
hemeO_c                       0            0     ...                 0
ahdt_c                        0            0     ...                 0
udcpdp_p                      0            0     ...                 0
fad_c                         0            1     ...                 0

                    biomass3_78  biomass3_79  biomass3_81  biomass3_82  \
dhmpt_c                       1            0            0            0
3ohodcoa_c                    0            0            0            0
LalaDgluMdapDala_p            0            0            0            0
prpncoa_c                     0            0            0            0
14dhncoa_c                    0            0            1            0
btcoa_c                       0            0            0            0
hdd2coa_c                     0            0            0            0
mococdp_c                     0            0            0            0
forcoa_c                      0            0            0            0
moco_c                        0            0            0            0
LalaDgluMdap_e                0            1            0            0
q8_c                          0            0            0            0
25drapp_c                     1            0            0            0
kdolipid4_c                   0            0            0            1
anhgm3p_c                     0            0            0            0
stcoa_c                       0            0            0            0
5mtr_p                        0            0            0            0
5mtr_e                        0            0            0            0
uamag_c                       0            1            0            0
dtbt_c                        0            0            0            0
murein5px4px4p_p              0            0            0            0
nadphx__S_c                   0            1            0            0
sbzcoa_c                      0            0            0            0
LalaDgluMdapDala_c            0            1            0            0
lipa_cold_c                   0            0            1            0
spmd_e                        0            0            0            0
fad_p                         0            0            0            0
ugmd_c                        0            0            0            0
murein4px4p4p_p               0            0            0            0
uaagmda_c                     0            0            0            0
...                         ...          ...          ...          ...
anhm4p_c                      0            1            0            0
dhpmp_c                       0            0            0            0
pap_c                         0            1            1            0
pmtcoa_c                      0            0            0            0
6hmhptpp_c                    1            0            0            0
nadphx__R_c                   0            0            0            0
3hhcoa_c                      0            0            0            0
5mtr_c                        0            0            0            0
2oph_c                        0            0            0            0
dann_c                        1            0            0            0
3hodcoa_c                     0            0            0            0
dhpt_c                        0            0            0            0
hxcoa_c                       0            0            0            0
thmmp_c                       0            0            0            0
murein4px4p_p                 1            0            0            0
gtspmd_c                      0            0            0            1
q8h2_c                        1            0            0            0
2ohph_c                       0            0            0            1
2ombzl_c                      0            0            0            0
rbflvrd_c                     0            0            0            0
3oddcoa_c                     0            0            0            0
succoa_c                      0            0            0            0
fmnh2_c                       0            0            0            0
prbamp_c                      0            0            0            0
2omhmbl_c                     0            0            0            0
ribflv_c                      0            0            0            0
hemeO_c                       0            0            0            0
ahdt_c                        0            0            0            0
udcpdp_p                      0            0            0            1
fad_c                         0            0            0            0

                    biomass3_83  biomass3_87  biomass3_90  biomass3_91  \
dhmpt_c                       0            0            0            0
3ohodcoa_c                    0            0            0            0
LalaDgluMdapDala_p            0            0            0            0
prpncoa_c                     0            0            0            0
14dhncoa_c                    1            0            0            0
btcoa_c                       0            0            0            0
hdd2coa_c                     0            0            0            0
mococdp_c                     0            0            1            0
forcoa_c                      0            1            1            0
moco_c                        0            0            0            1
LalaDgluMdap_e                0            0            1            1
q8_c                          0            0            1            0
25drapp_c                     0            0            0            0
kdolipid4_c                   0            0            0            0
anhgm3p_c                     0            0            0            0
stcoa_c                       0            0            0            0
5mtr_p                        0            0            0            0
5mtr_e                        0            0            0            0
uamag_c                       0            0            1            0
dtbt_c                        0            0            0            0
murein5px4px4p_p              0            0            0            0
nadphx__S_c                   0            0            0            1
sbzcoa_c                      0            0            0            0
LalaDgluMdapDala_c            0            0            0            0
lipa_cold_c                   0            0            0            0
spmd_e                        0            0            0            0
fad_p                         0            0            0            0
ugmd_c                        0            0            1            0
murein4px4p4p_p               0            0            0            0
uaagmda_c                     0            1            0            0
...                         ...          ...          ...          ...
anhm4p_c                      0            0            0            0
dhpmp_c                       0            0            1            1
pap_c                         0            0            0            0
pmtcoa_c                      1            0            0            0
6hmhptpp_c                    0            1            0            0
nadphx__R_c                   0            1            1            0
3hhcoa_c                      0            0            0            1
5mtr_c                        0            0            0            0
2oph_c                        0            0            0            0
dann_c                        0            1            0            0
3hodcoa_c                     1            0            0            0
dhpt_c                        0            0            0            1
hxcoa_c                       0            0            0            0
thmmp_c                       0            0            0            0
murein4px4p_p                 1            0            0            0
gtspmd_c                      0            0            0            0
q8h2_c                        0            0            0            0
2ohph_c                       0            0            0            0
2ombzl_c                      0            0            0            0
rbflvrd_c                     0            0            0            0
3oddcoa_c                     0            0            0            0
succoa_c                      0            0            1            0
fmnh2_c                       0            1            0            0
prbamp_c                      0            0            0            0
2omhmbl_c                     0            0            0            0
ribflv_c                      0            0            0            0
hemeO_c                       0            0            0            0
ahdt_c                        0            0            0            0
udcpdp_p                      1            0            0            1
fad_c                         0            0            0            0

                    biomass3_92
dhmpt_c                       0
3ohodcoa_c                    0
LalaDgluMdapDala_p            0
prpncoa_c                     0
14dhncoa_c                    0
btcoa_c                       0
hdd2coa_c                     1
mococdp_c                     0
forcoa_c                      0
moco_c                        0
LalaDgluMdap_e                0
q8_c                          0
25drapp_c                     0
kdolipid4_c                   0
anhgm3p_c                     0
stcoa_c                       0
5mtr_p                        0
5mtr_e                        0
uamag_c                       0
dtbt_c                        0
murein5px4px4p_p              1
nadphx__S_c                   0
sbzcoa_c                      0
LalaDgluMdapDala_c            0
lipa_cold_c                   0
spmd_e                        0
fad_p                         1
ugmd_c                        0
murein4px4p4p_p               0
uaagmda_c                     1
...                         ...
anhm4p_c                      0
dhpmp_c                       0
pap_c                         0
pmtcoa_c                      0
6hmhptpp_c                    0
nadphx__R_c                   0
3hhcoa_c                      0
5mtr_c                        0
2oph_c                        0
dann_c                        0
3hodcoa_c                     0
dhpt_c                        0
hxcoa_c                       0
thmmp_c                       0
murein4px4p_p                 0
gtspmd_c                      0
q8h2_c                        0
2ohph_c                       0
2ombzl_c                      0
rbflvrd_c                     1
3oddcoa_c                     0
succoa_c                      0
fmnh2_c                       0
prbamp_c                      0
2omhmbl_c                     1
ribflv_c                      0
hemeO_c                       0
ahdt_c                        0
udcpdp_p                      0
fad_c                         0

[186 rows x 116 columns]
Im in loop 1 and I have 0 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abcf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445954d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aba70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a91b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1478c7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445909e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e592d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e595a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e599e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e523f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e526c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e525f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e59a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52c68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e52fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b5dd83638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791de60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d7e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791db90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0791d488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14755b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b38c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445568c0>
Im in loop 2 and I have 35 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ac68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0755b5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a70e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a32050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a321b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a32320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a72d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a32518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abfc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07b144d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a32680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a17170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a172d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a175a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14755440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a17638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a179e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1476ea70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a1ad88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479ef38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a023f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445627a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a17cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a02758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07995908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a32d88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445569e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cf38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cbd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446255a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ada70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146872d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146877a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146873f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146875f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445275a8>
Im in loop 3 and I have 72 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab4d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07979f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1474e3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b079518c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0797a2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0797a440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0797a710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0797ab48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0765cd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0792e0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07979128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07979290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f86c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b079795f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b05a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07951c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07979cf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b41b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b40e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446257e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445510e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44551128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445512d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445513f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445511b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445270e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553e5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553e440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553edd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475bef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1473d050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1479e560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b079d46c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553e2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146877e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a79758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553e0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553e248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553ea70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147740e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1553ee18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e0a3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e0a248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e0ac68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e0a128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e0a170>
                  biomass1_1  biomass1_2  biomass1_8  biomass1_11  \
thmpp_c                    0           0           0            0
thmnp_c                    0           1           0            0
3otdcoa_c                  0           0           0            0
2ommbl_c                   0           0           0            0
25drapp_c                  0           0           0            0
2omph_c                    0           0           0            1
prbamp_c                   1           0           0            1
mocogdp_c                  1           0           0            1
dhf_c                      0           0           0            1
anhgm4p_c                  0           0           0            0
3hhdcoa_c                  1           0           0            0
lipidA_c                   0           1           0            0
murein5p5p_p               0           0           0            0
prfp_c                     0           0           0            0
bmocogdp_c                 0           0           0            1
n8aspmd_c                  0           0           0            1
murein4px4p_p              0           0           0            0
murein5p5p5p_p             0           0           0            0
sbzcoa_c                   0           0           1            0
LalaDgluMdap_e             0           0           0            0
um4p_c                     0           0           0            0
fadh2_c                    0           0           0            0
dpcoa_c                    0           0           0            0
ahdt_c                     0           0           0            1
murein5p3p_p               0           0           0            0
malcoa_c                   0           0           1            0
lipa_p                     0           0           1            0
murein5px4px4p_p           0           0           0            0
moco_c                     0           0           0            0
prpncoa_c                  0           0           0            0
...                      ...         ...         ...          ...
prlp_c                     0           1           0            0
5aprbu_c                   0           0           0            0
udcpdp_p                   0           0           0            0
anhgm3p_p                  1           0           0            0
udcpp_p                    0           1           0            0
5mta_c                     0           1           0            0
u23ga_c                    0           0           0            0
dc2coa_c                   0           0           0            0
murein3px3p_p              0           1           0            0
kdo2lipid4_e               0           1           1            0
ametam_c                   0           0           0            0
3ohodcoa_c                 0           0           0            0
nadphx__R_c                0           0           1            0
5fthf_c                    1           0           0            0
10fthf_c                   0           0           0            0
4mpetz_c                   0           0           0            0
odecoa_c                   0           1           1            0
dnad_c                     0           0           0            1
mptamp_c                   0           1           0            0
od2coa_c                   0           1           1            0
lipa_e                     0           1           0            0
hdd2coa_c                  0           0           0            0
colipa_e                   0           0           0            0
anhgm3p_c                  0           0           0            0
occoa_c                    0           0           0            0
ddcacoa_c                  0           0           0            0
2tpr3dpcoa_c               0           0           0            0
dhpmp_c                    0           0           0            0
2oph_c                     0           0           0            0
LalaDgluMdap_p             0           0           0            0

                  biomass1_14  biomass1_16  biomass1_19  biomass1_24  \
thmpp_c                     0            0            0            0
thmnp_c                     0            0            0            0
3otdcoa_c                   0            0            0            1
2ommbl_c                    0            0            0            1
25drapp_c                   0            0            0            0
2omph_c                     1            0            0            0
prbamp_c                    1            0            0            0
mocogdp_c                   0            0            0            1
dhf_c                       0            0            0            0
anhgm4p_c                   0            0            0            0
3hhdcoa_c                   0            0            1            0
lipidA_c                    0            0            0            0
murein5p5p_p                0            0            1            0
prfp_c                      0            0            0            0
bmocogdp_c                  0            0            1            0
n8aspmd_c                   0            0            0            0
murein4px4p_p               0            0            0            0
murein5p5p5p_p              0            0            0            1
sbzcoa_c                    0            0            1            0
LalaDgluMdap_e              0            0            0            1
um4p_c                      0            1            0            0
fadh2_c                     0            0            0            1
dpcoa_c                     0            1            1            0
ahdt_c                      0            1            0            0
murein5p3p_p                0            0            0            1
malcoa_c                    0            0            0            0
lipa_p                      0            0            0            0
murein5px4px4p_p            0            0            0            0
moco_c                      0            0            0            0
prpncoa_c                   0            0            0            0
...                       ...          ...          ...          ...
prlp_c                      0            0            0            0
5aprbu_c                    0            0            1            0
udcpdp_p                    0            0            0            0
anhgm3p_p                   0            0            0            0
udcpp_p                     0            0            0            0
5mta_c                      0            0            0            0
u23ga_c                     0            0            1            0
dc2coa_c                    1            0            0            1
murein3px3p_p               0            0            0            0
kdo2lipid4_e                0            1            0            0
ametam_c                    0            0            0            0
3ohodcoa_c                  1            0            0            0
nadphx__R_c                 0            0            1            1
5fthf_c                     1            0            0            0
10fthf_c                    1            0            0            0
4mpetz_c                    0            0            0            0
odecoa_c                    0            1            0            0
dnad_c                      0            0            0            0
mptamp_c                    0            0            0            0
od2coa_c                    0            0            1            0
lipa_e                      1            0            0            0
hdd2coa_c                   0            0            0            0
colipa_e                    0            0            0            0
anhgm3p_c                   0            0            0            1
occoa_c                     0            0            0            0
ddcacoa_c                   0            0            0            0
2tpr3dpcoa_c                0            0            0            0
dhpmp_c                     0            0            0            0
2oph_c                      0            0            0            0
LalaDgluMdap_p              0            0            0            0

                  biomass1_26  biomass1_27     ...       biomass3_77  \
thmpp_c                     0            0     ...                 0
thmnp_c                     0            0     ...                 0
3otdcoa_c                   0            0     ...                 0
2ommbl_c                    0            0     ...                 0
25drapp_c                   0            0     ...                 0
2omph_c                     0            0     ...                 0
prbamp_c                    0            0     ...                 0
mocogdp_c                   0            0     ...                 0
dhf_c                       0            0     ...                 0
anhgm4p_c                   0            0     ...                 1
3hhdcoa_c                   1            0     ...                 0
lipidA_c                    0            0     ...                 0
murein5p5p_p                0            1     ...                 0
prfp_c                      0            0     ...                 0
bmocogdp_c                  0            1     ...                 0
n8aspmd_c                   0            0     ...                 0
murein4px4p_p               0            0     ...                 0
murein5p5p5p_p              0            0     ...                 0
sbzcoa_c                    0            0     ...                 0
LalaDgluMdap_e              0            0     ...                 0
um4p_c                      0            0     ...                 0
fadh2_c                     0            0     ...                 0
dpcoa_c                     0            0     ...                 0
ahdt_c                      0            1     ...                 0
murein5p3p_p                0            0     ...                 0
malcoa_c                    0            0     ...                 0
lipa_p                      0            0     ...                 0
murein5px4px4p_p            0            0     ...                 1
moco_c                      0            0     ...                 0
prpncoa_c                   0            0     ...                 0
...                       ...          ...     ...               ...
prlp_c                      0            1     ...                 0
5aprbu_c                    1            0     ...                 0
udcpdp_p                    0            0     ...                 0
anhgm3p_p                   0            0     ...                 0
udcpp_p                     0            0     ...                 0
5mta_c                      0            0     ...                 0
u23ga_c                     0            0     ...                 1
dc2coa_c                    0            0     ...                 0
murein3px3p_p               0            0     ...                 0
kdo2lipid4_e                0            0     ...                 0
ametam_c                    0            0     ...                 1
3ohodcoa_c                  0            0     ...                 0
nadphx__R_c                 0            1     ...                 0
5fthf_c                     1            0     ...                 0
10fthf_c                    0            0     ...                 0
4mpetz_c                    1            0     ...                 0
odecoa_c                    0            0     ...                 1
dnad_c                      1            0     ...                 0
mptamp_c                    0            0     ...                 0
od2coa_c                    0            1     ...                 0
lipa_e                      0            0     ...                 0
hdd2coa_c                   0            0     ...                 0
colipa_e                    0            0     ...                 1
anhgm3p_c                   0            0     ...                 0
occoa_c                     0            0     ...                 0
ddcacoa_c                   0            0     ...                 0
2tpr3dpcoa_c                0            0     ...                 0
dhpmp_c                     0            0     ...                 0
2oph_c                      1            0     ...                 0
LalaDgluMdap_p              0            0     ...                 0

                  biomass3_78  biomass3_79  biomass3_81  biomass3_82  \
thmpp_c                     1            0            0            0
thmnp_c                     0            1            0            0
3otdcoa_c                   0            0            0            1
2ommbl_c                    0            0            0            0
25drapp_c                   0            0            0            0
2omph_c                     1            0            0            0
prbamp_c                    0            0            0            0
mocogdp_c                   0            0            0            0
dhf_c                       0            0            0            0
anhgm4p_c                   1            0            0            0
3hhdcoa_c                   0            0            0            0
lipidA_c                    0            0            0            0
murein5p5p_p                0            0            1            0
prfp_c                      0            0            0            0
bmocogdp_c                  0            1            0            0
n8aspmd_c                   0            0            0            0
murein4px4p_p               0            0            0            0
murein5p5p5p_p              0            1            0            0
sbzcoa_c                    0            0            0            0
LalaDgluMdap_e              0            0            0            0
um4p_c                      1            0            0            1
fadh2_c                     0            1            0            0
dpcoa_c                     0            0            0            1
ahdt_c                      0            1            0            0
murein5p3p_p                1            0            0            0
malcoa_c                    1            0            0            0
lipa_p                      0            0            0            0
murein5px4px4p_p            1            0            0            0
moco_c                      1            0            1            0
prpncoa_c                   0            0            0            0
...                       ...          ...          ...          ...
prlp_c                      1            0            0            0
5aprbu_c                    0            0            0            0
udcpdp_p                    0            0            0            0
anhgm3p_p                   1            0            1            0
udcpp_p                     0            1            0            0
5mta_c                      0            0            0            0
u23ga_c                     0            0            0            1
dc2coa_c                    0            0            0            0
murein3px3p_p               0            0            0            0
kdo2lipid4_e                0            0            0            0
ametam_c                    0            0            0            0
3ohodcoa_c                  0            0            0            1
nadphx__R_c                 0            0            0            1
5fthf_c                     0            0            0            0
10fthf_c                    0            0            0            0
4mpetz_c                    0            0            0            0
odecoa_c                    0            0            0            0
dnad_c                      0            0            1            0
mptamp_c                    0            0            0            0
od2coa_c                    1            0            0            0
lipa_e                      0            0            0            1
hdd2coa_c                   0            0            0            0
colipa_e                    0            0            1            0
anhgm3p_c                   0            0            0            1
occoa_c                     0            0            0            0
ddcacoa_c                   0            0            0            0
2tpr3dpcoa_c                0            0            0            0
dhpmp_c                     0            0            0            0
2oph_c                      0            0            1            0
LalaDgluMdap_p              0            1            0            0

                  biomass3_83  biomass3_84  biomass3_88  biomass3_89  \
thmpp_c                     0            0            1            0
thmnp_c                     0            0            0            0
3otdcoa_c                   0            0            1            0
2ommbl_c                    0            0            1            0
25drapp_c                   0            0            0            0
2omph_c                     0            0            0            0
prbamp_c                    1            0            1            1
mocogdp_c                   0            0            0            0
dhf_c                       0            0            0            0
anhgm4p_c                   0            0            0            0
3hhdcoa_c                   0            0            0            0
lipidA_c                    0            0            0            0
murein5p5p_p                0            0            0            0
prfp_c                      0            0            0            0
bmocogdp_c                  0            0            0            0
n8aspmd_c                   0            0            1            0
murein4px4p_p               0            0            0            0
murein5p5p5p_p              1            0            0            0
sbzcoa_c                    0            0            0            0
LalaDgluMdap_e              0            0            1            0
um4p_c                      0            0            0            0
fadh2_c                     0            0            0            0
dpcoa_c                     0            0            0            0
ahdt_c                      0            0            0            0
murein5p3p_p                0            1            1            1
malcoa_c                    0            0            0            0
lipa_p                      0            0            0            0
murein5px4px4p_p            0            1            0            0
moco_c                      0            0            0            0
prpncoa_c                   0            0            0            0
...                       ...          ...          ...          ...
prlp_c                      0            0            0            0
5aprbu_c                    1            1            0            0
udcpdp_p                    0            0            0            0
anhgm3p_p                   0            0            0            0
udcpp_p                     0            0            0            0
5mta_c                      0            0            0            0
u23ga_c                     0            0            0            0
dc2coa_c                    1            0            1            0
murein3px3p_p               0            0            0            0
kdo2lipid4_e                0            1            0            0
ametam_c                    0            0            1            0
3ohodcoa_c                  0            1            0            0
nadphx__R_c                 1            0            0            0
5fthf_c                     0            0            0            0
10fthf_c                    0            0            0            0
4mpetz_c                    1            1            0            0
odecoa_c                    0            0            0            0
dnad_c                      0            0            0            1
mptamp_c                    0            0            0            0
od2coa_c                    0            0            0            0
lipa_e                      0            0            0            0
hdd2coa_c                   0            0            0            0
colipa_e                    0            0            0            0
anhgm3p_c                   1            0            0            0
occoa_c                     0            0            0            0
ddcacoa_c                   0            0            0            0
2tpr3dpcoa_c                0            1            0            0
dhpmp_c                     0            1            0            0
2oph_c                      1            0            0            0
LalaDgluMdap_p              0            0            0            0

                  biomass3_91
thmpp_c                     0
thmnp_c                     0
3otdcoa_c                   0
2ommbl_c                    1
25drapp_c                   0
2omph_c                     0
prbamp_c                    1
mocogdp_c                   0
dhf_c                       0
anhgm4p_c                   0
3hhdcoa_c                   0
lipidA_c                    0
murein5p5p_p                0
prfp_c                      0
bmocogdp_c                  0
n8aspmd_c                   0
murein4px4p_p               0
murein5p5p5p_p              0
sbzcoa_c                    1
LalaDgluMdap_e              0
um4p_c                      0
fadh2_c                     0
dpcoa_c                     0
ahdt_c                      0
murein5p3p_p                0
malcoa_c                    0
lipa_p                      0
murein5px4px4p_p            0
moco_c                      0
prpncoa_c                   0
...                       ...
prlp_c                      0
5aprbu_c                    0
udcpdp_p                    0
anhgm3p_p                   0
udcpp_p                     0
5mta_c                      0
u23ga_c                     0
dc2coa_c                    0
murein3px3p_p               0
kdo2lipid4_e                0
ametam_c                    0
3ohodcoa_c                  0
nadphx__R_c                 0
5fthf_c                     0
10fthf_c                    1
4mpetz_c                    0
odecoa_c                    0
dnad_c                      0
mptamp_c                    0
od2coa_c                    0
lipa_e                      0
hdd2coa_c                   0
colipa_e                    0
anhgm3p_c                   0
occoa_c                     0
ddcacoa_c                   0
2tpr3dpcoa_c                1
dhpmp_c                     0
2oph_c                      1
LalaDgluMdap_p              0

[186 rows x 119 columns]
Im in loop 1 and I have 0 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b44604878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b5dd83638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a96c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9bd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445513f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073caf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073cafc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073caef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3ccf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445514d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445510e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073e8098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073e8200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b40e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073e84d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073e8638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1470eef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ca1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ca3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3f80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445568c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44590d40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b38c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b39e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f86c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b446245a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f82d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445954d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445953b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dfc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708c20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147084d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3cb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b078689e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07868488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a70e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445273f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445276c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073cacf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454aa70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b47e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f27e8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2b00>
Im in loop 2 and I have 40 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b445909e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8a0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abd40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acebd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a3f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b59e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c3b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445627a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad8c0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0755d1b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ad170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ad2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ad5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ad368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b070cfab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15d3c200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445624d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14791050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1470ec68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14755830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aba70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562998>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44562518>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452da70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0793cf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ab320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445abe18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad830>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ad248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454aab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d488>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ac68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d0e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15ace560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15ace200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acee60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acecb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15aceb90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14687320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15ace170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acec68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acea28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15aceb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15acedd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15aceea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15ace9e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15ace680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b15aced88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b0728d6c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077f4170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14708878>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8ad88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b155de680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e33e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556d88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44556f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8ac68>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aef80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44625e18>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073adf80>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14791560>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a72d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073b3098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073b3200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073b3368>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073b34d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b05f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a7b48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8acf8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8aef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8ab90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8aab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07f8a7a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1408d200>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1408d3b0>
Im in loop 3 and I have 87 valid individuals
4
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ba2b00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aeb48>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445626c8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445622d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44595248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b6669c680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f2440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ba23f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07ba2a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452d440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b3cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b39e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dd88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4452dfc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a9170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077da128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077da098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077da170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44624098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f82d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475b440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1470eb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a2d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b00e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077ef5a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077ef5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077ef050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077ef320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077efb00>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0758>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b0290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4453f128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b444f8440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b073ad320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d84d0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d83b0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d85a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d87a0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b41b8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445b4128>
<BOFdat.core.initial_population.Individual instance at 0x7f3b06e88ab8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b09e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742dd0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077feea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe440>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fee60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454ad88>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe098>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe248>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b4454a710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077feb90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe908>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8638>
<BOFdat.core.initial_population.Individual instance at 0x7f3b078c29e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077febd8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe680>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077fe050>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8710>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146872d8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147b0cb0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b077d8ea8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14701170>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14761e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14791ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445275f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445275a8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445273f8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b07a07ef0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146fc5f0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b14742320>
<BOFdat.core.initial_population.Individual instance at 0x7f3b44527290>
<BOFdat.core.initial_population.Individual instance at 0x7f3b1475bc20>
<BOFdat.core.initial_population.Individual instance at 0x7f3b147080e0>
<BOFdat.core.initial_population.Individual instance at 0x7f3b146fc950>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0f38>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a28>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0a70>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0fc8>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0b90>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445a0e60>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445aed40>
<BOFdat.core.initial_population.Individual instance at 0x7f3b445ae518>
                    biomass1_0  biomass1_1  biomass1_4  biomass1_5  \
murein4px4px4p_p             0           0           0           0
lipa_p                       0           1           0           0
pmtcoa_c                     0           0           0           0
spmd_p                       1           0           0           0
enlipa_e                     0           0           0           0
btn_c                        0           0           0           0
LalaLglu_c                   0           0           0           0
moco_c                       0           0           0           0
sbzcoa_c                     0           0           0           0
murein4px4p_p                0           0           0           0
dhf_c                        0           0           0           0
malcoame_c                   0           0           0           0
mlthf_c                      0           1           0           0
pap_c                        0           0           0           1
kdo2lipid4p_c                1           0           0           0
mococdp_c                    1           0           0           0
colipa_e                     0           0           0           0
spmd_e                       0           0           0           0
lipa_cold_c                  0           0           0           0
dann_c                       0           0           0           0
5fthf_c                      0           0           1           1
3hddcoa_c                    0           0           0           0
u3aga_c                      0           0           0           0
dcacoa_c                     0           0           1           0
ribflv_p                     0           0           0           0
murein5px4px4p_p             0           0           1           0
ugmd_c                       0           1           0           0
LalaDgluMdapDala_p           0           0           0           0
2tpr3dpcoa_c                 0           0           0           0
6hmhpt_c                     0           0           0           0
...                        ...         ...         ...         ...
3otdcoa_c                    0           0           0           0
uagmda_c                     0           1           0           0
10fthf_c                     0           0           0           0
occoa_c                      0           0           0           0
athtp_c                      0           0           1           0
lipa_e                       1           0           0           0
4r5au_c                      0           0           0           0
2ombzl_c                     0           0           0           0
3ohdcoa_c                    0           1           0           0
murein5p5p5p_p               0           0           0           0
LalaDgluMdapDala_c           0           0           0           0
thmpp_c                      0           0           0           0
3hodcoa_c                    0           0           0           0
aps_c                        1           0           1           0
uaagmda_c                    0           0           0           0
fmn_c                        0           0           0           0
ugmda_c                      0           0           0           0
paps_c                       1           0           0           0
3hhcoa_c                     0           0           0           0
u23ga_c                      0           0           0           0
lipa_cold_p                  0           0           0           1
ribflv_c                     0           0           1           1
q8_c                         0           0           0           0
hx2coa_c                     0           1           0           0
LalaDgluMdap_p               0           0           1           0
bmoco_c                      0           0           0           0
dhpt_c                       1           0           0           0
6hmhptpp_c                   1           0           0           0
mmcoa__S_c                   0           0           0           0
dnad_c                       1           0           0           0

                    biomass1_9  biomass1_10  biomass1_12  biomass1_13  \
murein4px4px4p_p             0            0            0            0
lipa_p                       0            0            0            0
pmtcoa_c                     0            0            0            0
spmd_p                       0            0            0            0
enlipa_e                     0            0            0            0
btn_c                        0            0            0            0
LalaLglu_c                   0            0            0            0
moco_c                       0            0            0            1
sbzcoa_c                     0            0            0            0
murein4px4p_p                1            0            0            0
dhf_c                        0            0            0            0
malcoame_c                   0            1            0            0
mlthf_c                      0            0            0            0
pap_c                        0            0            0            1
kdo2lipid4p_c                0            0            0            0
mococdp_c                    0            0            0            0
colipa_e                     0            0            0            1
spmd_e                       0            0            0            0
lipa_cold_c                  0            0            0            0
dann_c                       0            0            0            0
5fthf_c                      0            0            0            0
3hddcoa_c                    0            0            0            0
u3aga_c                      1            0            0            0
dcacoa_c                     0            0            0            1
ribflv_p                     0            0            0            0
murein5px4px4p_p             0            1            0            0
ugmd_c                       0            0            0            0
LalaDgluMdapDala_p           1            0            0            0
2tpr3dpcoa_c                 0            0            1            0
6hmhpt_c                     0            0            0            0
...                        ...          ...          ...          ...
3otdcoa_c                    0            0            0            0
uagmda_c                     1            0            0            0
10fthf_c                     0            0            0            1
occoa_c                      0            0            0            1
athtp_c                      0            0            0            0
lipa_e                       1            0            0            0
4r5au_c                      1            0            0            0
2ombzl_c                     0            0            0            0
3ohdcoa_c                    0            0            1            0
murein5p5p5p_p               0            1            0            0
LalaDgluMdapDala_c           0            0            0            0
thmpp_c                      0            0            0            0
3hodcoa_c                    0            0            0            0
aps_c                        0            1            0            0
uaagmda_c                    0            0            0            0
fmn_c                        0            0            0            0
ugmda_c                      0            1            0            0
paps_c                       1            0            0            0
3hhcoa_c                     0            0            0            0
u23ga_c                      0            0            0            0
lipa_cold_p                  1            0            0            0
ribflv_c                     0            0            0            1
q8_c                         0            0            0            0
hx2coa_c                     0            0            1            0
LalaDgluMdap_p               0            0            0            0
bmoco_c                      0            0            0            0
dhpt_c                       0            0            0            1
6hmhptpp_c                   1            0            0            1
mmcoa__S_c                   0            1            0            0
dnad_c                       1            0            0            1

                    biomass1_15  biomass1_16     ...       biomass3_65  \
murein4px4px4p_p              0            0     ...                 0
lipa_p                        1            1     ...                 0
pmtcoa_c                      0            0     ...                 0
spmd_p                        0            0     ...                 0
enlipa_e                      0            0     ...                 1
btn_c                         0            0     ...                 0
LalaLglu_c                    0            0     ...                 0
moco_c                        0            0     ...                 0
sbzcoa_c                      0            0     ...                 0
murein4px4p_p                 1            0     ...                 1
dhf_c                         0            0     ...                 0
malcoame_c                    0            0     ...                 0
mlthf_c                       0            0     ...                 0
pap_c                         0            0     ...                 0
kdo2lipid4p_c                 0            0     ...                 0
mococdp_c                     0            0     ...                 0
colipa_e                      0            0     ...                 1
spmd_e                        1            0     ...                 0
lipa_cold_c                   0            1     ...                 0
dann_c                        0            1     ...                 1
5fthf_c                       0            0     ...                 0
3hddcoa_c                     1            0     ...                 0
u3aga_c                       0            0     ...                 0
dcacoa_c                      0            0     ...                 0
ribflv_p                      0            0     ...                 0
murein5px4px4p_p              0            0     ...                 0
ugmd_c                        0            0     ...                 0
LalaDgluMdapDala_p            0            1     ...                 0
2tpr3dpcoa_c                  0            0     ...                 0
6hmhpt_c                      0            0     ...                 0
...                         ...          ...     ...               ...
3otdcoa_c                     0            0     ...                 0
uagmda_c                      0            0     ...                 0
10fthf_c                      0            0     ...                 0
occoa_c                       0            0     ...                 0
athtp_c                       0            0     ...                 0
lipa_e                        1            0     ...                 0
4r5au_c                       1            0     ...                 0
2ombzl_c                      0            0     ...                 0
3ohdcoa_c                     0            0     ...                 1
murein5p5p5p_p                0            0     ...                 0
LalaDgluMdapDala_c            0            0     ...                 0
thmpp_c                       0            1     ...                 0
3hodcoa_c                     0            1     ...                 0
aps_c                         0            0     ...                 1
uaagmda_c                     0            0     ...                 1
fmn_c                         0            0     ...                 0
ugmda_c                       0            0     ...                 0
paps_c                        0            0     ...                 0
3hhcoa_c                      0            0     ...                 0
u23ga_c                       0            0     ...                 0
lipa_cold_p                   0            0     ...                 0
ribflv_c                      1            0     ...                 0
q8_c                          0            0     ...                 0
hx2coa_c                      0            0     ...                 0
LalaDgluMdap_p                0            1     ...                 0
bmoco_c                       0            0     ...                 0
dhpt_c                        1            0     ...                 0
6hmhptpp_c                    0            0     ...                 0
mmcoa__S_c                    0            0     ...                 0
dnad_c                        1            1     ...                 0

                    biomass3_69  biomass3_71  biomass3_73  biomass3_80  \
murein4px4px4p_p              0            0            0            0
lipa_p                        0            0            0            0
pmtcoa_c                      0            0            0            0
spmd_p                        1            0            0            0
enlipa_e                      0            0            1            0
btn_c                         0            0            0            0
LalaLglu_c                    0            0            0            0
moco_c                        0            0            0            0
sbzcoa_c                      0            0            0            0
murein4px4p_p                 0            0            0            0
dhf_c                         0            0            0            0
malcoame_c                    0            0            0            0
mlthf_c                       0            0            0            0
pap_c                         0            0            0            0
kdo2lipid4p_c                 0            1            0            0
mococdp_c                     0            1            0            1
colipa_e                      0            0            0            0
spmd_e                        1            0            1            0
lipa_cold_c                   1            1            0            0
dann_c                        0            0            0            0
5fthf_c                       0            0            0            0
3hddcoa_c                     0            0            0            0
u3aga_c                       0            0            0            0
dcacoa_c                      0            0            0            1
ribflv_p                      1            0            0            0
murein5px4px4p_p              0            1            0            0
ugmd_c                        0            0            1            1
LalaDgluMdapDala_p            0            1            0            0
2tpr3dpcoa_c                  0            0            0            0
6hmhpt_c                      0            0            0            0
...                         ...          ...          ...          ...
3otdcoa_c                     0            0            0            0
uagmda_c                      0            0            0            0
10fthf_c                      0            0            0            0
occoa_c                       0            0            0            0
athtp_c                       0            1            0            0
lipa_e                        0            1            0            0
4r5au_c                       0            0            0            0
2ombzl_c                      0            0            0            0
3ohdcoa_c                     0            0            0            0
murein5p5p5p_p                0            0            0            0
LalaDgluMdapDala_c            0            0            0            0
thmpp_c                       0            0            0            0
3hodcoa_c                     0            0            0            0
aps_c                         0            0            0            0
uaagmda_c                     0            0            0            0
fmn_c                         0            0            0            0
ugmda_c                       0            0            0            0
paps_c                        0            0            0            0
3hhcoa_c                      1            1            0            1
u23ga_c                       1            0            0            0
lipa_cold_p                   0            0            0            0
ribflv_c                      0            0            0            1
q8_c                          0            0            0            0
hx2coa_c                      0            0            0            0
LalaDgluMdap_p                0            0            0            1
bmoco_c                       0            0            0            0
dhpt_c                        0            0            1            0
6hmhptpp_c                    0            0            0            1
mmcoa__S_c                    0            0            1            0
dnad_c                        0            0            0            0

                    biomass3_82  biomass3_83  biomass3_85  biomass3_87  \
murein4px4px4p_p              0            0            0            0
lipa_p                        0            0            0            0
pmtcoa_c                      0            0            0            0
spmd_p                        0            0            0            0
enlipa_e                      0            0            0            0
btn_c                         0            0            0            0
LalaLglu_c                    0            0            0            0
moco_c                        0            0            0            0
sbzcoa_c                      0            0            1            0
murein4px4p_p                 0            0            0            0
dhf_c                         0            0            0            0
malcoame_c                    1            1            0            0
mlthf_c                       0            0            1            0
pap_c                         0            0            1            0
kdo2lipid4p_c                 0            0            0            0
mococdp_c                     0            0            0            0
colipa_e                      0            0            0            0
spmd_e                        0            0            0            0
lipa_cold_c                   0            0            0            0
dann_c                        0            1            0            0
5fthf_c                       0            0            0            1
3hddcoa_c                     1            0            0            0
u3aga_c                       0            0            0            0
dcacoa_c                      0            0            0            0
ribflv_p                      0            0            0            1
murein5px4px4p_p              0            0            1            0
ugmd_c                        0            0            0            0
LalaDgluMdapDala_p            0            0            0            0
2tpr3dpcoa_c                  0            0            0            0
6hmhpt_c                      0            0            0            0
...                         ...          ...          ...          ...
3otdcoa_c                     0            1            0            0
uagmda_c                      0            1            0            0
10fthf_c                      0            0            0            0
occoa_c                       0            0            0            0
athtp_c                       0            0            1            0
lipa_e                        0            0            0            0
4r5au_c                       0            1            0            0
2ombzl_c                      0            0            0            0
3ohdcoa_c                     0            0            0            0
murein5p5p5p_p                0            0            0            0
LalaDgluMdapDala_c            0            0            0            0
thmpp_c                       0            1            0            0
3hodcoa_c                     0            0            0            0
aps_c                         0            1            0            0
uaagmda_c                     0            1            0            0
fmn_c                         0            0            0            0
ugmda_c                       0            0            0            0
paps_c                        0            0            0            0
3hhcoa_c                      0            0            0            0
u23ga_c                       1            0            0            0
lipa_cold_p                   0            0            0            0
ribflv_c                      0            0            0            0
q8_c                          0            0            0            0
hx2coa_c                      0            0            0            0
LalaDgluMdap_p                1            0            0            0
bmoco_c                       1            0            0            0
dhpt_c                        0            0            0            0
6hmhptpp_c                    0            1            0            0
mmcoa__S_c                    0            0            0            0
dnad_c                        0            1            0            0

                    biomass3_89
murein4px4px4p_p              1
lipa_p                        0
pmtcoa_c                      0
spmd_p                        0
enlipa_e                      0
btn_c                         0
LalaLglu_c                    0
moco_c                        0
sbzcoa_c                      0
murein4px4p_p                 0
dhf_c                         0
malcoame_c                    0
mlthf_c                       0
pap_c                         0
kdo2lipid4p_c                 0
mococdp_c                     0
colipa_e                      0
spmd_e                        0
lipa_cold_c                   0
dann_c                        0
5fthf_c                       0
3hddcoa_c                     0
u3aga_c                       1
dcacoa_c                      0
ribflv_p                      0
murein5px4px4p_p              0
ugmd_c                        1
LalaDgluMdapDala_p            0
2tpr3dpcoa_c                  0
6hmhpt_c                      1
...                         ...
3otdcoa_c                     0
uagmda_c                      1
10fthf_c                      0
occoa_c                       0
athtp_c                       0
lipa_e                        0
4r5au_c                       1
2ombzl_c                      0
3ohdcoa_c                     0
murein5p5p5p_p                0
LalaDgluMdapDala_c            0
thmpp_c                       0
3hodcoa_c                     0
aps_c                         0
uaagmda_c                     0
fmn_c                         0
ugmda_c                       0
paps_c                        0
3hhcoa_c                      0
u23ga_c                       0
lipa_cold_p                   0
ribflv_c                      0
q8_c                          1
hx2coa_c                      0
LalaDgluMdap_p                0
bmoco_c                       0
dhpt_c                        1
6hmhptpp_c                    0
mmcoa__S_c                    0
dnad_c                        0

[186 rows x 122 columns]

3.3.4. Generate optimal biomass compositions

Each individual in the population defines a different biomass composition that can be evaluated for fitness. Here, the evaluation function is the gene essentiality prediction. Ideally the constraints applied by the biomass objective function on the model would force flux through certain reactions as it happens in vivo. Namely, metabolites that the cell need to produce in order to double should be represented in the biomass objective function. The in silico knock-out of genes would cut the flux through the reaction and the cell would not be able to grow, replicating in vivo gene essentiality.

Single-gene knock-out is executed for each biomass composition generated. Both in vivo and in vitro essentiality are converted in boolean vectors of essential and non-essential genes. The distance between the two vectors can then be determined using standard distance metrics (Hamming) or the Matthews Correlation Coefficient (MCC). The metric is used as a measure of fitness. The MCC is then maximized throughout the evolution, selecting biomass compositions that yield the highest. The standard genetic operators mutation and cross-over are operated on the inviduals to create genetic diversity.

#Files for the genetic algorithm
path_to_model = 'data/iML1515.json'
initial_population_path = 'data/Populations/test_pop_1.csv'
exp_essentiality_path = 'data/glucose_essentiality.csv'
base_biomass = 'data/bofdat_step2.csv'
logbook_name = 'data/Outputs/logbook_test_pop_1.csv'
hall_of_fame_name = 'data/Outputs/hof_test_pop_1.csv'

step3.find_metabolites(path_to_model,
                       initial_population_path,
                       exp_essentiality_path,
                       base_biomass=True,logbook=True,history=False,processes=None,
                       logbook_name=logbook_name,hall_of_fame_name=hall_of_fame_name)

Using default GA parameters
initializing toolbox
{'fitness_size': -0.25, 'indpb': 0.005, 'MUTPB': 0.1, 'distance_measure': 'mcc', 'NGEN': 20, 'CXPB': 0.5, 'fitness_distance': 1.0}
made it to the GA
{'hall_of_fame_size': 1000, 'logbook_name': 'data/Outputs/logbook_test_pop_1.csv', 'hall_of_fame_name': 'data/Outputs/hof_test_pop_1.csv'}
I will evaluate the initial population
8
Fitnesses that will be attributed to individuals [(0.5831338574121917, 20), (0.6059394725741493, 20), (0.6393695697555211, 20), (0.6674475878654471, 20), (0.6769364729767546, 20), (0.5954531704191854, 20), (0.6663692082440766, 20), (0.6029438370809624, 20), (0.6119153310764769, 20), (0.6173702451382262, 20), (0.6624072660575369, 20), (0.7021886829961169, 20), (0.6262830123495685, 20), (0.6637836843155994, 20), (0.7072431657430097, 20), (0.6236043104240845, 20), (0.6537646020336324, 20), (0.6386318032265479, 20), (0.6311775953880013, 20), (0.6313771731445313, 20), (0.62898418389611, 20), (0.6962006490528011, 20), (0.6541594175602851, 20), (0.6363378308482635, 20), (0.6173494220638511, 20), (0.6181267818987809, 20), (0.5847166496571535, 20), (0.6156846301292822, 20), (0.5756636157403037, 20), (0.6182296807882196, 20), (0.6710129539275436, 20), (0.6463839341058546, 20), (0.6372050808082818, 20), (0.6927832679985074, 20), (0.6218423147059814, 20), (0.6743112458611458, 20), (0.6780045612960975, 20), (0.6246090658572868, 20), (0.624363549840846, 20), (0.5955011610011258, 20), (0.6380882233864997, 20), (0.6781683367472692, 20), (0.6405840173692732, 20), (0.6084079008572052, 20), (0.6781089804550924, 20), (0.6579837675790179, 20), (0.6473448634361862, 20), (0.6194403818497947, 20), (0.6340607402542529, 20), (0.6248857458701229, 20), (0.5908248289192787, 20), (0.6597772630160379, 20), (0.7218983877128748, 20), (0.573528182269623, 20), (0.6128254222491804, 20), (0.6158426702613037, 20), (0.6433403336692858, 20), (0.6727192129257922, 20), (0.6874980194524505, 20), (0.6784715994367295, 20), (0.6012194397225543, 20), (0.6156996209164165, 20), (0.6317081763968765, 20), (0.6699446284375671, 20), (0.5919277007298216, 20), (0.6492961841351435, 20), (0.6473448634361862, 20), (0.6710129539275435, 20), (0.6205978789288492, 20), (0.6237170243985821, 20), (0.6590711050873344, 20), (0.578296005824905, 20), (0.6363662631895888, 20), (0.6666046482141045, 20), (0.669944628437567, 20), (0.6102869452368186, 20), (0.6142204181849615, 20), (0.6333498195822204, 20), (0.6088768337827852, 20), (0.6543664966289205, 20), (0.6927793889570437, 20), (0.6038153269883321, 20), (0.600014655256627, 20), (0.6342461135614833, 20), (0.711566200730716, 20), (0.6181267818987808, 20), (0.6792841491552973, 20), (0.635193969178685, 20), (0.6123952250519719, 20), (0.6019326143142889, 20), (0.6605567032972461, 20), (0.6040320549249182, 20), (0.6473448634361861, 20), (0.6400207106346736, 20), (0.6485415721045326, 20), (0.6249870802269492, 20), (0.6473448634361862, 20), (0.6527340681584806, 20), (0.6786358079846995, 20), (0.6236043104240845, 20), (0.635534003050213, 20), (0.5968989337453762, 20), (0.64155478582065, 20), (0.6084438618520577, 20), (0.6527340681584806, 20), (0.7044072493503126, 20), (0.6356285205105173, 20), (0.6758760563932494, 20), (0.6507458547536423, 20), (0.6579837675790178, 20), (0.6438980650008356, 20), (0.5914505405207039, 20), (0.6590711050873345, 20), (0.6543199419109901, 20), (0.6425851934780317, 20)]
Finished evaluating initial population
Starting generation 0
doing a crossover
crossover actually worked
doing a crossover
crossover yielded identical individuals
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover yielded identical individuals
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
generating a new individual
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
doing a crossover
crossover actually worked
I will evaluate 54 invalid individuals, wish me luck!
8

ERROR:root:Internal Python error in the inspect module.
Below is the traceback from this internal error.

Traceback (most recent call last):
  File "/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.py", line 1132, in get_records
    return _fixed_getinnerframes(etb, number_of_lines_of_context, tb_offset)
  File "/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.py", line 313, in wrapped
    return f(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.py", line 358, in _fixed_getinnerframes
    records = fix_frame_records_filenames(inspect.getinnerframes(etb, context))
  File "/usr/lib/python2.7/inspect.py", line 1049, in getinnerframes
    framelist.append((tb.tb_frame,) + getframeinfo(tb, context))
  File "/usr/lib/python2.7/inspect.py", line 1009, in getframeinfo
    filename = getsourcefile(frame) or getfile(frame)
  File "/usr/lib/python2.7/inspect.py", line 454, in getsourcefile
    if hasattr(getmodule(object, filename), '__loader__'):
  File "/usr/lib/python2.7/inspect.py", line 497, in getmodule
    f = getabsfile(module)
  File "/usr/lib/python2.7/inspect.py", line 466, in getabsfile
    _filename = getsourcefile(object) or getfile(object)
  File "/usr/lib/python2.7/inspect.py", line 451, in getsourcefile
    if os.path.exists(filename):
  File "/usr/lib/python2.7/genericpath.py", line 26, in exists
    os.stat(path)
KeyboardInterrupt

---------------------------------------------------------------------------
IndexError                                Traceback (most recent call last)
/usr/local/lib/python2.7/dist-packages/IPython/core/interactiveshell.pyc in run_code(self, code_obj, result)
   2897             if result is not None:
   2898                 result.error_in_exec = sys.exc_info()[1]
-> 2899             self.showtraceback()
   2900         else:
   2901             outflag = 0

/usr/local/lib/python2.7/dist-packages/IPython/core/interactiveshell.pyc in showtraceback(self, exc_tuple, filename, tb_offset, exception_only)
   1824                     except Exception:
   1825                         stb = self.InteractiveTB.structured_traceback(etype,
-> 1826                                             value, tb, tb_offset=tb_offset)
   1827
   1828                     self._showtraceback(etype, value, stb)

/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.pyc in structured_traceback(self, etype, value, tb, tb_offset, number_of_lines_of_context)
   1410         self.tb = tb
   1411         return FormattedTB.structured_traceback(
-> 1412             self, etype, value, tb, tb_offset, number_of_lines_of_context)
   1413
   1414

/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.pyc in structured_traceback(self, etype, value, tb, tb_offset, number_of_lines_of_context)
   1318             # Verbose modes need a full traceback
   1319             return VerboseTB.structured_traceback(
-> 1320                 self, etype, value, tb, tb_offset, number_of_lines_of_context
   1321             )
   1322         else:

/usr/local/lib/python2.7/dist-packages/IPython/core/ultratb.pyc in structured_traceback(self, etype, evalue, etb, tb_offset, number_of_lines_of_context)
   1202                 structured_traceback_parts += formatted_exception
   1203         else:
-> 1204             structured_traceback_parts += formatted_exception[0]
   1205
   1206         return structured_traceback_parts

IndexError: string index out of range

ERROR:tornado.general:Uncaught exception, closing connection.
Traceback (most recent call last):
  File "/usr/local/lib/python2.7/dist-packages/zmq/eventloop/zmqstream.py", line 414, in _run_callback
    callback(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/tornado/stack_context.py", line 277, in null_wrapper
    return fn(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 283, in dispatcher
    return self.dispatch_shell(stream, msg)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 235, in dispatch_shell
    handler(stream, idents, msg)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 421, in execute_request
    self._abort_queues()
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 637, in _abort_queues
    self._abort_queue(stream)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 662, in _abort_queue
    poller.poll(50)
  File "/usr/local/lib/python2.7/dist-packages/zmq/sugar/poll.py", line 99, in poll
    return zmq_poll(self.sockets, timeout=timeout)
  File "zmq/backend/cython/_poll.pyx", line 116, in zmq.backend.cython._poll.zmq_poll (zmq/backend/cython/_poll.c:2036)
  File "zmq/backend/cython/checkrc.pxd", line 12, in zmq.backend.cython.checkrc._check_rc (zmq/backend/cython/_poll.c:2418)
    PyErr_CheckSignals()
KeyboardInterrupt
ERROR:tornado.general:Uncaught exception, closing connection.
Traceback (most recent call last):
  File "/usr/local/lib/python2.7/dist-packages/zmq/eventloop/zmqstream.py", line 440, in _handle_events
    self._handle_recv()
  File "/usr/local/lib/python2.7/dist-packages/zmq/eventloop/zmqstream.py", line 472, in _handle_recv
    self._run_callback(callback, msg)
  File "/usr/local/lib/python2.7/dist-packages/zmq/eventloop/zmqstream.py", line 414, in _run_callback
    callback(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/tornado/stack_context.py", line 277, in null_wrapper
    return fn(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 283, in dispatcher
    return self.dispatch_shell(stream, msg)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 235, in dispatch_shell
    handler(stream, idents, msg)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 421, in execute_request
    self._abort_queues()
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 637, in _abort_queues
    self._abort_queue(stream)
  File "/usr/local/lib/python2.7/dist-packages/ipykernel/kernelbase.py", line 662, in _abort_queue
    poller.poll(50)
  File "/usr/local/lib/python2.7/dist-packages/zmq/sugar/poll.py", line 99, in poll
    return zmq_poll(self.sockets, timeout=timeout)
  File "zmq/backend/cython/_poll.pyx", line 116, in zmq.backend.cython._poll.zmq_poll (zmq/backend/cython/_poll.c:2036)
  File "zmq/backend/cython/checkrc.pxd", line 12, in zmq.backend.cython.checkrc._check_rc (zmq/backend/cython/_poll.c:2418)
    PyErr_CheckSignals()
KeyboardInterrupt

3.3.5. Cluster the metabolic end goals

The output of a genetic algorithm may vary from one initial population to another. To get a sense of what would be an optimal result, it is generally advised to run more than one evolution and aggregate the results. BOFdat does so by clustering the metabolites that appeared most frequently in the optimal result of every evolution. The distance matrix for every metabolite in the network is generated and reduced to the most frequent metabolites. Hierarchical clustering is then applied to the reduced distance matrix in order to generate clusters of metabolic end goals that can be used for curation.

#Necessary inputs
data_path = '/home/jean-christophe/Documents/Maitrise_UCSD/BOFdat_qual/Paper_figures/data/Outputs_10-07/'
outpath = '/home/jean-christophe/Documents/Maitrise_UCSD/BOFdat_qual/Paper_figures/'
path_to_model = 'data/iML1515.json'
eps = 6
CONNECTIVITY_THRESHOLD = 15
BASELINE=0.2
show_frequency = True
show_matrix = True

#Run the clustering
selected_metabolites = step3.cluster_metabolites(data_path,
                              path_to_model,
                              CONNECTIVITY_THRESHOLD,
                              BASELINE,
                              show_frequency,
                              show_matrix,
                              frequency_fig_name=os.path.join(outpath,'frequency_fig.svg'),
                              matrix_fig_name=os.path.join(outpath,'matrix_fig.svg'))

{'frequency_fig_name': '/home/jean-christophe/Documents/Maitrise_UCSD/BOFdat_qual/Paper_figures/frequency_fig.svg', 'matrix_fig_name': '/home/jean-christophe/Documents/Maitrise_UCSD/BOFdat_qual/Paper_figures/matrix_fig.svg'}

3.3.6. Determine stoichiometric coefficients

from BOFdat.util.update import determine_coefficients
WEIGHT_FRACTION = 0.05
model = cobra.io.load_json_model(path_to_model)
bd_step3 = determine_coefficients(selected_metabolites,model,WEIGHT_FRACTION)

3.3.7. Update

#Get the input from the previous step
from BOFdat.util import update
path_to_biomass = 'data/bofdat_step2.csv'
bd_step2 = update.convert_to_dictionary(path_to_biomass)
bd_step3.update(bd_step2)
update.save_biomass(bd_step3,'data/bofdat_step3.csv')

/home/jean-christophe/Documents/Maitrise_UCSD/BOFdat/BOFdat/util/update.py:22 UserWarning: File has 3 columns, assuming index on first column

76